Expression of Transglutaminase 1 in Human Epidermis

[6] Use of T7 RNA polymerase to direct expression of cloned genes

1990 • 6,681 citations

Normal keratinization in a spontaneously immortalized aneuploid human keratinocyte cell line.

1988 • 4,008 citations

Transglutaminases: multifunctional cross‐linking enzymes that stabilize tissues

1991 • 999 citations

Purification and some properties of streptococcal protein G, a novel IgG-binding reagent.

1984 • 791 citations

The cornified envelope of terminally differentiated human epidermal keratinocytes consists of cross-linked protein

1977 • 532 citations

Transglutaminases: Protein Cross-Linking Enzymes in Tissues and Body Fluids

1994 • 504 citations

Keratinocyte-specific transglutaminase of cultured human epidermal cells: Relation to cross-linked envelope formation and terminal differentiation

1985 • 479 citations

Identification of a major keratinocyte cell envelope protein, loricrin

1990 • 420 citations

Structure and evolution of the human involucrin gene

1986 • 393 citations

Characterization of human loricrin. Structure and function of a new class of epidermal cell envelope proteins.

1991 • 305 citations

Protein composition of cornified cell envelopes of epidermal keratinocytes

1994 • 246 citations

Molecular Characterization and Evolution of the SPRR Family of Keratinocyte Differentiation Markers Encoding Small Proline-Rich Proteins

1993 • 204 citations

[46] Transglutaminases

1985 • 202 citations

Synthetic peptides corresponding to keratin subunits elicit highly specific antibodies.

1984 • 186 citations

Cornified Cell Envelope

1990 • 184 citations

Involucrin—Structure and Role in Envelope Assembly

1993 • 181 citations

The structure of human trichohyalin. Potential multiple roles as a functional EF-hand-like calcium-binding protein, a cornified cell envelope precursor, and an intermediate filament-associated (cross-linking) protein

1993 • 160 citations

Cornifin, a cross-linked envelope precursor in keratinocytes that is down-regulated by retinoids.

1992 • 158 citations

The deduced sequence of the novel protransglutaminase E (TGase3) of human and mouse

1993 • 117 citations

Protransglutaminase E from guinea pig skin. Isolation and partial characterization.

1990 • 110 citations

Keratolinin: the soluble substrate of epidermal transglutaminase from human and bovine tissue.

1984 • 107 citations

The human loricrin gene.

1992 • 105 citations

epsilon-(gamma-Glutamyl)lysine cross-links in human stratum corneum.

1977 • 101 citations

Effects of UV, 4NQO and TPA on gene expression in cultured human epidermal keratinocytes

1987 • 100 citations

The Mechanism of Interaction of Filaggrin with Intermediate Filaments

1993 • 100 citations

The conserved H1 domain of the type II keratin 1 chain plays an essential role in the alignment of nearest neighbor molecules in mouse and human keratin 1/keratin 10 intermediate filaments at the two- to four-molecule level of structure.

1993 • 99 citations

Structure and organization of the human transglutaminase 1 gene.

1992 • 98 citations

Type I Keratinocyte Transglutaminase: Expression in Human Skin and Psoriasis

1992 • 96 citations

Acylation of Keratinocyte Transglutaminase by Palmitic and Myristic Acids in the Membrane Anchorage Region

1989 • 92 citations

The Cornified Envelope: A Key Structure of Terminally Differentiating Keratinocytes

1993 • 90 citations

The glutamine residues reactive in transglutaminase-catalyzed cross-linking of involucrin.

1988 • 87 citations

The complete amino acid sequence of the human transglutaminase K enzyme deduced from the nucleic acid sequences of cDNA clones.

1991 • 86 citations

Structural features of glutamine substrates for human plasma factor XIIIa (activated blood coagulation factor XIII).

1980 • 81 citations

Purification of keratinocyte transglutaminase and its expression during squamous differentiation.

1989 • 78 citations

The Molecular Biology of Skin

1976 • 75 citations

The structure of the transglutaminase 1 enzyme. Deletion cloning reveals domains that regulate its specific activity and substrate specificity.

1994 • 74 citations

Phosphorylated cystatin α is a natural substrate of epidermal transglutaminase for formation of skin cornified envelope

1992 • 73 citations

Overexpression of human loricrin in transgenic mice produces a normal phenotype.

1993 • 68 citations

Biophysical characterization of involucrin reveals a molecule ideally suited to function as an intermolecular cross-bridge of the keratinocyte cornified envelope.

1992 • 67 citations

Isolation and characterization of the human spr1 gene and its regulation of expression by phorbol ester and cyclic AMP

1993 • 58 citations

Molecular cloning of mouse epidermal cystatin A and detection of regulated expression in differentiation and tumorigenesis

1988 • 57 citations

Proteolytic release of keratinocyte transglutaminase

1990 • 52 citations

Evidence for filaggrin as a component of the cell envelope of the newborn rat

1988 • 52 citations

Expression of Keratinocyte Transglutamine mRNA Revealed by In Situ Hybridization

1992 • 49 citations

Distribution of Fodrin in the Keratinocyte In Vivo and In Vitro

1990 • 39 citations

Retinoic acid controls expression of epidermal transglutaminase at the pre-translational level

1989 • 27 citations