Involucrin—Structure and Role in Envelope Assembly

Transglutaminases: multifunctional cross‐linking enzymes that stabilize tissues

1991 • 999 citations

Transglutaminases

1980 • 818 citations

Presence in human epidermal cells of a soluble protein precursor of the cross-linked envelope: Activation of the cross-linking by calcium ions

1979 • 792 citations

Transglutaminases

1984 • 589 citations

The cornified envelope of terminally differentiated human epidermal keratinocytes consists of cross-linked protein

1977 • 532 citations

Keratinocyte-specific transglutaminase of cultured human epidermal cells: Relation to cross-linked envelope formation and terminal differentiation

1985 • 479 citations

Identification of a major keratinocyte cell envelope protein, loricrin

1990 • 420 citations

Structure and evolution of the human involucrin gene

1986 • 393 citations

Involucrin synthesis and tissue assembly by keratinocytes in natural and cultured human epithelia.

1981 • 351 citations

The keratinocyte as differentiated cell type.

1980 • 260 citations

Structure, function, and differentiation of the keratinocyte

1989 • 238 citations

Enzymatic cross-linking of involucrin and other proteins by keratinocyte particulates in vitro

1985 • 235 citations

Molecular and Catalytic Properties of Transglutaminases

1973 • 201 citations

Biosynthetic pathways of filaggrin and loricrin—two major proteins expressed by terminally differentiated epidermal keratinocytes

1990 • 187 citations

Cornifin, a cross-linked envelope precursor in keratinocytes that is down-regulated by retinoids.

1992 • 158 citations

The Membrane Protein of Horny Cells**From the Department of Dermatology, Boston University School of Medicine, Boston University Medical Center, Boston, Mass.

1966 • 150 citations

FORMATION OF EPIDERMIS BY SERIALLY CULTIVATED HUMAN EPIDERMAL CELLS TRANSPLANTED AS AN EPITHELIUM TO ATHYMIC MICE

1980 • 139 citations

Human epidermal transglutaminase. Preparation and properties.

1976 • 138 citations

Regulation of type I (epidermal) transglutaminase mRNA levels during squamous differentiation: down regulation by retinoids.

1989 • 119 citations

Mechanism of Action of Guinea Pig Liver Transglutaminase

1970 • 119 citations

Protransglutaminase E from guinea pig skin. Isolation and partial characterization.

1990 • 110 citations

Keratolinin: the soluble substrate of epidermal transglutaminase from human and bovine tissue.

1984 • 107 citations

Morphological and Biochemical Characterization of the Cornified Envelopes from Human Epidermal Keratinocytes of Different Origin

1988 • 105 citations

Mechanism of Action of Guinea Pig Liver Transglutaminase

1969 • 102 citations

epsilon-(gamma-Glutamyl)lysine cross-links in human stratum corneum.

1977 • 101 citations

Plasma membrane changes during keratinization

1966 • 94 citations

Acylation of Keratinocyte Transglutaminase by Palmitic and Myristic Acids in the Membrane Anchorage Region

1989 • 92 citations

Isolation, purification and characterization of bovine epidermal transglutaminase

1976 • 89 citations

Tissue-specific and differentiation-appropriate expression of the human involucrin gene in transgenic mice: an abnormal epidermal phenotype

1993 • 89 citations

Structural features of glutamine substrates for transglutaminases. Role of extended interactions in the specificity of human plasma factor XIIIa and of the guinea pig liver enzyme.

1984 • 89 citations

The glutamine residues reactive in transglutaminase-catalyzed cross-linking of involucrin.

1988 • 87 citations

Structural features of glutamine substrates for human plasma factor XIIIa (activated blood coagulation factor XIII).

1980 • 81 citations

Biophysical characterization of involucrin reveals a molecule ideally suited to function as an intermolecular cross-bridge of the keratinocyte cornified envelope.

1992 • 67 citations

Remodeling of the involucrin gene during primate evolution

1988 • 67 citations

Structural features of glutamine substrates for transglutaminases. Specificities of human plasma factor XIIIa and the guinea pig liver enzyme toward synthetic peptides.

1981 • 66 citations

Immunoperoxidase staining for involucrin

1982 • 65 citations

Evidence that Involucrin Is a Covalently Linked Constituent of Highly Purified Cultured Keratinocyte Cornified Envelopes

1993 • 62 citations

Identification and Subcellular Distribution of Cornified Envelope Precursor Proteins in the Transformed Human Keratinocyte Line SV-K14

1987 • 62 citations

A minimum‐surface mechanism to account for the organization of cells into columns in the mammalian epidermis

1976 • 60 citations

Proteolytic release of keratinocyte transglutaminase

1990 • 52 citations

Evidence for filaggrin as a component of the cell envelope of the newborn rat

1988 • 52 citations

Involucrin acts as a transglutaminase substrate at multiple sites

1986 • 44 citations

Consecutive actions of different gene-altering mechanisms in the evolution of involucrin.

1992 • 43 citations

Phorbol ester-stimulated phosphorylation of keratinocyte transglutaminase in the membrane anchorage region

1990 • 33 citations

Stable Expression of Transfected Human Involucrin Gene in Various Cell Types: Evidence for In Situ Cross-Linking by Type I and Type II Transglutaminase

1991 • 19 citations

The pancornulins: A group of basic low molecular weight proteins in mammalian epidermis and epithelium that may function as cornified envelope precursors

1990 • 18 citations

Deleted Work

1955 • 0 citations