Transcriptional repression at a distance through exclusion of activator binding in vivo

Methods in Yeast Genetics

1988 • 4,905 citations

A multiprotein mediator of transcriptional activation and its interaction with the C-terminal repeat domain of RNA polymerase II

1994 • 1,064 citations

Stimulation of GAL4 Derivative Binding to Nucleosomal DNA by the Yeast SWI/SNF Complex

1994 • 853 citations

Nucleosome disruption and enhancement of activator binding by a human SW1/SNF complex

1994 • 766 citations

Heme regulates transcription of the CYC1 gene of S. cerevisiae via an upstream activation site

1983 • 667 citations

Plasmid construction by homologous recombination in yeast

1987 • 560 citations

Repression domain of the yeast global repressor Tup1 interacts directly with histones H3 and H4.

1996 • 460 citations

Nucleosome loss activates yeast downstream promoters in vivo

1988 • 456 citations

Regulation of gene expression by oxygen in Saccharomyces cerevisiae

1992 • 404 citations

The SWI-SNF complex: a chromatin remodeling machine?

1995 • 379 citations

RNA Polymerase II Holoenzyme Contains SWI/SNF Regulators Involved in Chromatin Remodeling

1996 • 364 citations

Yeast HAP1 activator binds to two upstream activation sites of different sequence

1987 • 317 citations

Active repression mechanisms of eukaryotic transcription repressors

1996 • 308 citations

IME1, a positive regulator gene of meiosis in S. cerevisiae

1988 • 303 citations

Silencers, silencing, and heritable transcriptional states

1992 • 296 citations

Cloning of yeast HAP5: a novel subunit of a heterotrimeric complex required for CCAAT binding.

1995 • 276 citations

Control of meiotic gene expression in Saccharomyces cerevisiae

1994 • 274 citations

Yeast HAP2 and HAP3 activators both bind to the CYC1 upstream activation site, UAS2, in an interdependent manner

1987 • 255 citations

Yeast global transcriptional regulators Sin4 and Rgr1 are components of mediator complex/RNA polymerase II holoenzyme.

1995 • 247 citations

The price of repression

1995 • 232 citations

Nucleosomes are positioned with base pair precision adjacent to the alpha 2 operator in Saccharomyces cerevisiae.

1991 • 203 citations

Drosophila Polycomb-group regulated chromatin inhibits the accessibility of a trans-activator to its target DNA.

1995 • 187 citations

Activation of meiosis and sporulation by repression of the RME1 product in yeast

1986 • 186 citations

A transcriptional cascade governs entry into meiosis in Saccharomyces cerevisiae.

1989 • 177 citations

Involvement of the SIN4 global transcriptional regulator in the chromatin structure of Saccharomyces cerevisiae.

1992 • 162 citations

Stable nucleosome positioning and complete repression by the yeast alpha 2 repressor are disrupted by amino-terminal mutations in histone H4.

1992 • 160 citations

REGULATION OF MATING AND MEIOSIS IN YEAST BY THE MATING-TYPE REGION

1976 • 159 citations

Mutations that suppress the deletion of an upstream activating sequence in yeast: involvement of a protein kinase and histone H3 in repressing transcription in vivo.

1993 • 144 citations

Identification of genes required for alpha 2 repression in Saccharomyces cerevisiae.

1995 • 123 citations

Bipartite Structure of an Early Meiotic Upstream Activation Sequence from Saccharomyces cerevisiae

1993 • 120 citations

Transcriptional Repression in Eukaryotes

1993 • 118 citations

Transcriptional repression directed by the yeast α2 protein in vitro

1994 • 118 citations

Role of IME1 expression in regulation of meiosis in Saccharomyces cerevisiae.

1990 • 110 citations

Mediator of transcriptional regulation

1996 • 103 citations

Probes of chromatin accessibility in the Drosophila bithorax complex respond differently to Polycomb-mediated repression.

1996 • 102 citations

Genetic and physical interactions between yeast RGR1 and SIN4 in chromatin organization and transcriptional regulation.

1995 • 97 citations

Chromatin-mediated transcription repression in yeast

1995 • 94 citations

The yeast activator HAP1--a GAL4 family member--binds DNA in a directly repeated orientation.

1994 • 93 citations

The yeast RME1 gene encodes a putative zinc finger protein that is directly repressed by a1-alpha 2.

1991 • 84 citations

TSF3, a global regulatory protein that silences transcription of yeast GAL genes, also mediates repression by alpha 2 repressor and is identical to SIN4.

1993 • 77 citations

Repression by the yeast meiotic inhibitor RME1.

1993 • 73 citations

Mediator of transcriptional regulation

1996 • 67 citations

Requirement for RGR1 and SIN4 in RME1-dependent repression in Saccharomyces cerevisiae.

1994 • 63 citations

Rme1, a negative regulator of meiosis, is also a positive activator of G1 cyclin gene expression.

1995 • 61 citations

rme1 Mutation of Saccharomyces cerevisiae: map position and bypass of mating type locus control of sporulation.

1981 • 59 citations

37 A Combinatorial Regulatory Circuit in Budding Yeast

1992 • 53 citations

A Transcriptional Cascade Governs Entry into Meiosis in Saccharomyces cerevisiae

1989 • 48 citations

Post-transcriptional regulation of IME1 determines initiation of meiosis in Saccharomyces cerevislae

1993 • 43 citations

Involvement of the SIN4 Global Transcriptional Regulator in the Chromatin Structure of Saccharomyces cerevisiae

1992 • 39 citations

Nucleosome Positioning and Transcription

1993 • 33 citations

Role of IME1 Expression in Regulation of Meiosis in Saccharomyces cerevisiae

1990 • 32 citations

Regulatory mechanisms in meiosis

1993 • 31 citations

TSF3, a Global Regulatory Protein That Silences Transcription of Yeast GAL Genes, Also Mediates Repression by α2 Repressor and Is Identical to SIN4

1993 • 30 citations

Accessibility of α2-Repressed Promoters to the Activator Gal4

1996 • 22 citations

rme1 Mutation of Saccharomyces cerevisiae: Map Position and Bypass of Mating Type Locus Control of Sporulation

1981 • 10 citations