The enamel knot as a signaling center in the developing mouse tooth

Sonic hedgehog mediates the polarizing activity of the ZPA

1993 • 2,313 citations

Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity

1993 • 2,146 citations

Msx1 deficient mice exhibit cleft palate and abnormalities of craniofacial and tooth development

1994 • 1,271 citations

Development of several organs that require inductive epithelial-mesenchymal interactions is impaired in LEF-1-deficient mice.

1994 • 969 citations

Identification of BMP-4 as a signal mediating secondary induction between epithelial and mesenchymal tissues during early tooth development

1993 • 908 citations

Floor plate and motor neuron induction by vhh-1, a vertebrate homolog of hedgehog expressed by the notochord

1994 • 869 citations

Compartment boundaries and the control of Drosopfiffa limb pattern by hedgehog protein

1994 • 842 citations

Sonic hedgehog and Fgf-4 act through a signaling cascade and feedback loop to integrate growth and patterning of the developing limb bud

1994 • 801 citations

A positive feedback loop coordinates growth and patterning in the vertebrate limb

1994 • 702 citations

Fgf-4 expression during gastrulation, myogenesis, limb and tooth development in the mouse

1992 • 676 citations

Spatial organization of the epithelium and the role of neural crest cells in the initiation of the mammalian tooth germ

1988 • 659 citations

Positional signalling and specification of digits in chick limb morphogenesis

1975 • 588 citations

Fibroblast growth factors induce additional limb development from the flank of chick embryos

1995 • 578 citations

The induction of odontogenesis in non-dental mesenchyme combined with early murine mandibular arch epithelium

1987 • 556 citations

Control of cell pattern in the neural tube: Motor neuron induction by diffusible factors from notochord and floor plate

1993 • 470 citations

Bone morphogenetic proteins and a signalling pathway that controls patterning in the developing chick limb

1994 • 465 citations

Regulation of organogenesis. Common molecular mechanisms regulating the development of teeth and other organs.

1995 • 439 citations

Evidence for the role of the enamel knot as a control center in mammalian tooth cusp formation: non-dividing cells express growth stimulating Fgf-4 gene.

1994 • 427 citations

Colocalization of BMP 7 and BMP 2 RNAs suggests that these factors cooperatively mediate tissue interactions during murine development

1995 • 424 citations

Induction of a second neural axis by the mouse node

1994 • 420 citations

FGF-4 and BMP-2 have opposite effects on limb growth

1993 • 377 citations

Tissue interactions in embryonic mouse tooth germs: II. The inductive role of the dental papilla

1970 • 319 citations

THE ONTOGENY OF MOLAR PATTERN

1956 • 285 citations

Even-numbered rhombomeres control the apoptotic elimination of neural crest cells from odd-numbered rhombomeres in the chick hindbrain

1993 • 260 citations

The homeobox gene Hox 7.1 has specific regional and temporal expression patterns during early murine craniofacial embryogenesis, especially tooth development in vivo and in vitro

1991 • 256 citations

Differential expression of the HMG box factors TCF-1 and LEF-1 during murine embryogenesis

1993 • 249 citations

The initiation of the limb bud: Growth factors, Hox genes, and retinoids

1995 • 170 citations

Expression of syndecan gene is induced early, is transient, and correlates with changes in mesenchymal cell proliferation during tooth organogenesis

1991 • 118 citations

Localization of HstI transcripts to the apical ectodermal ridge in the mouse embryo

1992 • 91 citations

Involvement of the Sonic Hedgehog Gene in Chick Feather Formation

1995 • 84 citations

Dorso-ventral patterning in the neural tube

1993 • 35 citations