K-ras codon 12 mutations in biliary tract tumors detected by polymerase chain reaction denaturing gradient gel electrophoresis

A genetic model for colorectal tumorigenesis

1990 • 11,800 citations

p53 Mutations in Human Cancers

1991 • 8,133 citations

Genetic Alterations during Colorectal-Tumor Development

1988 • 6,691 citations

ras GENES

1987 • 3,818 citations

Most human carcinomas of the exocrine pancreas contain mutant c-K-ras genes

1988 • 2,121 citations

Prevalence of ras gene mutations in human colorectal cancers

1987 • 1,866 citations

Attachment of a 40-base-pair G + C-rich sequence (GC-clamp) to genomic DNA fragments by the polymerase chain reaction results in improved detection of single-base changes.

1989 • 1,295 citations

Detection of human papilloma virus in paraffin-embedded tissue using the polymerase chain reaction.

1988 • 748 citations

KRAS codon 12 mutations occur very frequently in pancreatic adenocarcinomas

1988 • 620 citations

A dot-blot screening procedure for mutated ras oncogenes using synthetic oligodeoxynucleotides

1986 • 351 citations

High frequency of Ki‐ras codon 12 mutations in pancreatic adenocarcinomas

1989 • 295 citations

Analysis of RAS oncogene mutations in human lymphoid malignancies.

1988 • 226 citations

Analysis of ras gene mutations in biliary and pancreatic tumors by polymerase chain reaction and direct sequencing

1990 • 143 citations

Frequency and Types of Point Mutation at the 12th Codon of the c‐Ki‐ras Gene Found in Pancreatic Cancers from Japanese Patients

1989 • 128 citations

Distinguishing Pancreatic Carcinoma From Other Periampullary Carcinomas by Analysis of Mutations in the Kirsten-ras Oncogene

1991 • 109 citations

Frequent Glycine‐to‐Aspartic Acid Mutations at Codon 12 of c‐Ki‐ras Gene in Human Pancreatic Cancer in Japanese

1990 • 102 citations

Papillary and follicular thyroid carcinomas show a different pattern of ras oncogene mutation

1989 • 97 citations

Four human carcinoma cell lines with novel mutations in position 12 of c-K-ras oncogene

1986 • 89 citations

Low Incidence of Point Mutation of c‐Ki‐ras and N‐ras Oncogenes in Human Hepatocellular Carcinoma

1989 • 75 citations

Review: Biologic heterogeneity of cancer metastases

1987 • 56 citations

Point Mutations of c‐ras Genes in Human Bladder Cancer and Kidney Cancer

1990 • 42 citations