Heterogenous expression of cell-surface antigens in normal epithelia and their tumours, revealed by monoclonal antibodies

Identification of the gastrointestinal and pancreatic cancer-associated antigen detected by monoclonal antibody 19-9 in the sera of patients as a mucin.

1983 • 591 citations

GD3, a prominent ganglioside of human melanoma. Detection and characterisation by mouse monoclonal antibody.

1982 • 579 citations

A spectrum of monoclonal antibodies reactive with human mammary tumor cells.

1981 • 565 citations

Monoclonal antibodies against human milk‐fat globule membranes detecting differentiation antigens of the mammary gland and its tumors

1984 • 510 citations

The Major Histocompatibility Complex of the Mouse

1979 • 423 citations

Distribution of epithelial membrane antigen in normal and neoplastic tissues and its value in diagnostic tumor pathology

1981 • 404 citations

Monoclonal antibody to murine embryos defines a stage-specific embryonic antigen expressed on mouse embryos and human teratocarcinoma cells

1982 • 366 citations

Differentiation antigens expressed by epithelial cells in the lactating breast are also detectable in breast cancers

1981 • 331 citations

Complexity of expression of antigenic determinants, recognized by monoclonal antibodies HMFG-1 and HMFG-2, in normal and malignant human mammary epithelial cells.

1983 • 331 citations

Graft-versus-host disease induces expression of Ia antigen in rat epidermal cells and gut epithelium

1981 • 284 citations

Monoclonal antibody to keratin filaments, specific for glandular epithelia and their tumors. Use in surgical pathology.

1983 • 268 citations

Tumor heterogeneity.

1984 • 264 citations

Expression of Ia antigen on epidermal keratinocytes in graft-versus-host disease

1981 • 262 citations

Identification of a human neuroectodermal tumor antigen (OFA-I-2) as ganglioside GD2.

1982 • 242 citations

Generation of monoclonal antibodies reacting with normal and cancer cells of human breast.

1983 • 230 citations

Characterization of a human melanoma-associated ganglioside antigen defined by a monoclonal antibody, 4.2.

1982 • 217 citations

Monoclonal antibodies directed against the human Leb blood group antigen.

1981 • 212 citations

Definition of antigenic heterogeneity and modulation among human mammary carcinoma cell populations using monoclonal antibodies to tumor-associated antigens.

1983 • 193 citations

Monoclonal antibodies to the human mammary gland

1982 • 189 citations

The monoclonal antibody directed to difucosylated type 2 chain (Fuc alpha 1 leads to 2Gal beta 1 leads to 4[Fuc alpha 1 leads to 3]GlcNAc; Y Determinant).

1983 • 184 citations

Tissue- and developmental stage-specific forms of a neural cell surface antigen linked to differences in glycosylation of a common polypeptide.

1982 • 167 citations

Isolation and Characterization of Mucin-Like Glycoprotein in Human Milk Fat Globule Membrane

1982 • 162 citations

Immunohistochemical localization of the mouse stage-specific embryonic antigen 1 in human tissues and tumors.

1983 • 155 citations

Distribution of HLA class 1 antigens in normal human tissue and in mammary cancer.

1981 • 153 citations

Phenotypic drift of metastatic and cell‐surface properties of mammary adenocarcinoma cell clones during growth in vitro

1981 • 143 citations

A NEW MARKER FOR HUMAN CANCER CELLS. 2. IMMUNOHISTOCHEMICAL DETECTION OF THE Ca ANTIGEN IN HUMAN TISSUES WITH THE Ca1 ANTIBODY

1982 • 128 citations

Atypical endocrine tumors of the lung.

1981 • 127 citations

Heterogeneity in the expression of HLA and tumor-associated antigens by surgically removed and cultured breast carcinoma cells.

1983 • 125 citations

Many monoclonal antibodies with an apparent specificity for certain lung cancers are directed against a sugar sequence found in lacto-N-fucopentaose III

1983 • 124 citations

Implications of immunological heterogeneity of tumours

1979 • 117 citations

Experimental systems for analysis of the malignant phenotype

1982 • 116 citations

Monoclonal antibodies to the human mammary gland

1982 • 110 citations

Detection of cell surface and intracellular antigens by human monoclonal antibodies. Hybrid cell lines derived from lymphocytes of patients with malignant melanoma.

1983 • 110 citations

Cellular heterogeneity in tumours

1983 • 109 citations

Immunochemical analysis of the determinant recognized by a monoclonal antibody (MBr1) which specifically binds to human mammary epithelial cells.

1983 • 103 citations

Neutral glycolipid antigens as developmental markers of mouse teratocarcinoma and early embryos: an immunologic and chemical analysis.

1982 • 102 citations

The prognostic significance of two epithelial membrane antigens expressed by human mammary carcinomas

1984 • 100 citations

Epithelial membrane antigen: Partial purification, assay and properties

1983 • 98 citations

Distribution of Monoclonal Antibody-Defined Monosialoganglioside in Normal and Cancerous Human Tissues: An Immunoperoxidase Study

1983 • 92 citations

Biological and Clinical Implications of Lymphocyte Hybridomas: Tumor Therapy with Monoclonal Antibodies

1983 • 91 citations

Mouse monoclonal antibody F-3 recognizes the difucosyl type-2 blood group structure

1983 • 89 citations

A monoclonal antibody, NCRC‐11, raised to human breast carcinoma. 1. Production and immunohistological characterization

1984 • 87 citations

Biological behavior of human breast carcinoma-associated antigens expressed during cellular proliferation.

1983 • 85 citations

The membrane antigens of human colorectal cancer cells: Demonstration with monoclonal antibodies of heterogeneity within and between tumours and of anomalous expression of HLA-DR

1983 • 81 citations

Some properties and applications of monoclonal antibodies

1981 • 81 citations

Do metastases arise from pre-existing subpopulations of cancer cells?

1983 • 71 citations

Relationship Between Antigen Density and Immunotherapeutic Response Elicited by Monoclonal Antibodies Against Solid Tumors<xref ref-type="fn" rid="FN2">2</xref><xref ref-type="fn" rid="FN3">3</xref>

1984 • 69 citations

Is heterogeneous expression of HLA-DR antigens and CEA along with DNA-profile variations evidence of phenotypic instability and clonal proliferation in human large bowel carcinomas?

1983 • 60 citations

Expression of the OKT monoclonal antibody defined antigenic determinants in malignancy

1981 • 58 citations

Preparation and identification of human breast epithelial cells in culture

1980 • 56 citations

Two mouse hybridoma antibodies against human milk-fat globules recognise the I(MA) antigenic determinant β-d-Galp-(1→4)-β-d-GlcpNAc-(1→6)

1983 • 56 citations

Biology of disease. Monoclonal antibodies and tumor-associated antigens.

1983 • 55 citations

Monoclonal Antibody (F5) to Human Prostate Antigen

1983 • 54 citations

The presence of HLA-DR antigens on lactating human breast epithelium and milk fat globule membranes.

1980 • 53 citations

Use of monoclonal antibodies in detection of melanoma-associated antigens in intact human tumors.

1982 • 52 citations

Comparison of rates of phenotypic variability in surface antigen expression in normal and cancerous human breast epithelial cells.

1983 • 51 citations

Monoclonal antibodies and human tumor pathology

1982 • 43 citations

Modulation of phenotype in cultures of human milk epithelial cells and its relation to the expression of a membrane antigen

1983 • 43 citations

Differential cell adhesion may result from nonspecific interactions between cell surface glycoproteins

1978 • 38 citations

Antigenic subsets of human breast epithelial cells distinguished by monoclonal antibodies.

1984 • 38 citations

Reactivity Spectrum of 30 Monoclonal Antimelanoma Antibodies to a Panel of 28 Melanoma and Control Cell Lines

1982 • 36 citations

Immunohistochemical localization of prostate carcinoma-associated antigens.

1983 • 32 citations

Clonal analysis of morphological phenotype in cultured mammary epithelial cells from human milk

1982 • 26 citations

Monoclonal antibody against A1 Lewis d antigen produced by the hybridoma immunized with a pulmonary carcinoma.

1982 • 24 citations

Heterogeneity of beta 2-microglobulin in human breast carcinoma.

1981 • 23 citations

The use of monoclonal antibodies for histopathologic diagnosis of human malignancy.

1982 • 21 citations

Production of human T-lymphocyte clones. I. Monoclonal culture and functional cytotoxic maturation

1981 • 16 citations

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