Essential role of Drosophila Hdac1 in homeotic gene silencing

The Genome Sequence of Drosophila melanogaster

2000 • 5,882 citations

A gene complex controlling segmentation in Drosophila

1978 • 3,668 citations

Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase

2000 • 3,355 citations

The Transcriptional Coactivators p300 and CBP Are Histone Acetyltransferases

1996 • 2,873 citations

Homeobox genes and axial patterning

1992 • 2,688 citations

Potent and specific inhibition of mammalian histone deacetylase both in vivo and in vitro by trichostatin A.

1990 • 1,835 citations

Epigenetic mechanisms of gene regulation

1996 • 1,097 citations

Stabilization of Chromatin Structure by PRC1, a Polycomb Complex

1999 • 794 citations

The Dermatomyositis-Specific Autoantigen Mi2 Is a Component of a Complex Containing Histone Deacetylase and Nucleosome Remodeling Activities

1998 • 791 citations

Three proteins define a class of human histone deacetylases related to yeast Hda1p

1999 • 744 citations

ATP-dependent remodeling and acetylation as regulators of chromatin fluidity

1999 • 705 citations

HDA1 and RPD3 are members of distinct yeast histone deacetylase complexes that regulate silencing and transcription

1996 • 623 citations

Transcriptional repression by YY1 is mediated by interaction with a mammalian homolog of the yeast global regulator RPD3

1996 • 541 citations

Transcriptional repression mediated by the human polycomb-group protein EED involves histone deacetylation

1999 • 518 citations

Gene disruptions using P transposable elements: an integral component of the Drosophila genome project.

1995 • 472 citations

Dosage-dependent modifiers of polycomb and antennapedia mutations in Drosophila.

1988 • 460 citations

A functional interaction between the histone deacetylase Rpd3 and the corepressor Groucho in Drosophila development

1999 • 441 citations

Histone deacetylases: silencers for hire

2000 • 429 citations

A group of genes controlling the spatial expression of the bithorax complex in Drosophila

1985 • 413 citations

The Drosophila Polycomb Group Gene pleiohomeotic Encodes a DNA Binding Protein with Homology to the Transcription Factor YY1

1998 • 400 citations

THE POLYCOMB AND TRITHORAX GROUP PROTEINS OF DROSOPHILA: Trans-Regulators of Homeotic Gene Function

1995 • 390 citations

NuRD and SIN3

2000 • 384 citations

Molecular and Genetic Organization of The Antennapedia Gene Complex of Drosophila melanogaster

1990 • 360 citations

The Drosophila Fab-7 Chromosomal Element Conveys Epigenetic Inheritance during Mitosis and Meiosis

1998 • 360 citations

dMi-2, a Hunchback-Interacting Protein That Functions in Polycomb Repression

1998 • 349 citations

Polycomb and polyhomeotic are constituents of a multimeric protein complex in chromatin of Drosophila melanogaster.

1992 • 335 citations

The FlyBase Database of the Drosophila Genome Projects and community literature

1999 • 316 citations

In vivo binding pattern of a trans-regulator of homoeotic genes in Drosophila melanogaster

1989 • 302 citations

The Drosophila trithorax group proteins BRM, ASH1 and ASH2 are subunits of distinct protein complexes

1998 • 287 citations

Regulation of the Ultrabithorax gene of drosophila by other bithorax complex genes

1985 • 255 citations

Epigenetic Inheritance of Active Chromatin After Removal of the Main Transactivator

1999 • 239 citations

SMRTER, a Drosophila Nuclear Receptor Coregulator, Reveals that EcR-Mediated Repression Is Critical for Development

1999 • 216 citations

The molecular genetics of the bithorax complex of Drosophila: characterization of the products of the Abdominal-B domain.

1989 • 214 citations

The polyhomeotic gene of Drosophila encodes a chromatin protein that shares polytene chromosome-binding sites with Polycomb.

1992 • 193 citations

dMi-2 and ISWI chromatin remodelling factors have distinct nucleosome binding and mobilization properties

2000 • 186 citations

Regulatory elements of the bithorax complex that control expression along the anterior-posterior axis.

1990 • 162 citations

Osa associates with the Brahma chromatin remodeling complex and promotes the activation of some target genes

1999 • 150 citations

A Drosophila ESC-E(Z) Protein Complex Is Distinct from Other Polycomb Group Complexes and Contains Covalently Modified ESC

2000 • 150 citations

The Polycomb Group Protein Complex of Drosophila melanogaster Has Different Compositions at Different Target Genes

1997 • 147 citations

The Polycomb group gene Posterior Sex Combs encodes a chromosomal protein

1993 • 141 citations

Temporal pattern of alcohol dehydrogenase gene transcription reproduced by Drosophila stage-specific embryonic extracts

1988 • 129 citations

Discrete Polycomb-binding sites in each parasegmental domain of the bithorax complex

1995 • 119 citations

The Rpd3 histone deacetylase is required for segmentation of the Drosophila embryo

1999 • 115 citations

Comparison of germline mosaics of genes in the Polycomb group of Drosophila melanogaster.

1995 • 112 citations

Histone deacetylase is a component of the internal nuclear matrix.

1991 • 110 citations

Transcriptional silencing of homeotic genes in drosophila

1995 • 100 citations

Chromosomal localization links the SIN3-RPD3 complex to the regulation of chromatin condensation, histone acetylation and gene expression

2000 • 81 citations

The trithorax-group and Polycomb-group chromatin modifiers: implications for disease

1999 • 79 citations

Mutational Analysis of a Histone Deacetylase in Drosophila melanogaster: Missense Mutations Suppress Gene Silencing Associated With Position Effect Variegation

2000 • 75 citations

The origin and utility of histone deacetylases

1997 • 50 citations

Functional Reconstruction of trans Regulation of the Ultrabithorax Promoter by the Products of Two Antagonistic Genes, trithorax and Polycomb

1995 • 47 citations

Transcriptional Repression by XPc1, a New Polycomb Homolog in Xenopus laevis Embryos, Is Independent of Histone Deacetylase

1999 • 28 citations

Xenopus HDm, a maternally expressed histone deacetylase, belongs to an ancient family of acetyl-metabolizing enzymes

1997 • 28 citations