Protein C and protein S clinical perspectives

Deficiency of protein C in congenital thrombotic disease.

1981 • 1,260 citations

Protein C prevents the coagulopathic and lethal effects of Escherichia coli infusion in the baboon.

1987 • 836 citations

Identification of an endothelial cell cofactor for thrombin-catalyzed activation of protein C.

1981 • 831 citations

Isolation of a membrane-bound cofactor for thrombin-catalyzed activation of protein C.

1982 • 709 citations

Trousseau's syndrome and other manifestations of chronic disseminated coagulopathy in patients with neoplasms: clinical, pathophysiologic, and therapeutic features.

1977 • 674 citations

A new vitamin K-dependent protein. Purification from bovine plasma and preliminary characterization.

1976 • 634 citations

A comparison of human prothrombin, factor IX (Christmas factor), factor X (Stuart factor), and protein S

1977 • 582 citations

TROUSSEAUʼS SYNDROME AND OTHER MANIFESTATIONS OF CHRONIC DISSEMINATED COAGULOPATHY IN PATIENTS WITH NEOPLASMS

1977 • 547 citations

Plasma protein S deficiency in familial thrombotic disease

1984 • 516 citations

Human Plasma Protein C

1979 • 511 citations

Recurrent Venous Thromboembolism in Patients with a Partial Deficiency of Protein S

1984 • 507 citations

Regulation of activated protein C by a new protein. A possible function for bovine protein S.

1980 • 460 citations

Actions and Interactions of Antithrombin and Heparin

1975 • 449 citations

Homozygous Protein C Deficiency Manifested by Massive Venous Thrombosis in the Newborn

1984 • 444 citations

Congenital Protein C Deficiency and Venous Thromboembolism

1983 • 408 citations

Hereditary Protein S Deficiency: Clinical Manifestations

1987 • 391 citations

Functional and immunologic protein S levels are decreased during pregnancy

1986 • 347 citations

INHERITED PROTEIN C DEFICIENCY AND COUMARIN-RESPONSIVE CHRONIC RELAPSING PURPURA FULMINANS IN A NEWBORN INFANT

1983 • 346 citations

Activated protein C decreases plasminogen activator-inhibitor activity in endothelial cell-conditioned medium

1985 • 305 citations

Protein C Deficiency in a Dutch Family with Thrombotic Disease

1982 • 287 citations

DEFICIENCIES OF PROTEIN C, AN INHIBITOR OF BLOOD COAGULATION

1982 • 224 citations

Neonatal purpura fulminans: a genetic disorder related to the absence of protein C in blood

1985 • 204 citations

Coumarin Necrosis Associated with Hereditary Protein C Deficiency

1984 • 197 citations

Protein C, an antithrombotic protein, is reduced in hospitalized patients with intravascular coagulation

1982 • 193 citations

Relationship between protein C antigen and anticoagulant activity during oral anticoagulation and in selected disease states.

1986 • 172 citations

Biosynthesis and secretion of factor VII, protein C, protein S, and the Protein C inhibitor from a human hepatoma cell line

1986 • 171 citations

Serial studies of protein C and its plasma inhibitor in patients with disseminated intravascular coagulation

1985 • 149 citations

Severe homozygous protein C deficiency

1984 • 134 citations

Activation of Purified Prothrombin to Autoprothrombin I or Autoprothrombin II (Platelet Cofactor II or Autoprothrombin II-A)

1961 • 131 citations

Identification and quantitation of protein S in human platelets

1985 • 119 citations

Successful Progressive Anticoagulation in a Severe Protein C Deficiency and Previous Skin Necrosis at the Initiation of Oral Anticoagulant Treatment

1984 • 109 citations

Decrease in protein C antigen and formation of an abnormal protein soon after starting oral anticoagulant therapy

1984 • 106 citations

Liver dysfunction rather than intravascular coagulation as the main cause of low protein C and antithrombin III in acute leukemia

1984 • 98 citations

Decline of proteins C and S and factors II, VII, IX and X during the initiation of warfarin therapy

1987 • 91 citations

The cofactor role of protein S in the acceleration of whole blood clot lysis by activated protein C in vitro

1986 • 91 citations

Liver dysfunction rather than intravascular coagulation as the main cause of low protein C and antithrombin III in acute leukemia

1984 • 75 citations

Decrease in protein C antigen and formation of an abnormal protein soon after starting oral anticoagulant therapy

1984 • 69 citations

Radioimmunoassays for Protein C and Factor X: Plasma Antigen Levels in Abnormal Hemostatic States

1984 • 59 citations

Protein C in Thromboembolic Disease

1985 • 55 citations

Plasma concentrations of the natural anticoagulants protein C and protein S in patients with proteinuria.

1985 • 48 citations

Low protein C in the neonatal period

1986 • 46 citations

Protein C activity in renal disease

1985 • 36 citations

Behaviour of Protein C Inhibitor in Intravascular Coagulation and Liver Disease

1984 • 29 citations

Effects of Oral Contraceptives and Obesity on Protein C Antigen

1985 • 28 citations

Treatment of Hereditary Protein C Deficiency with Stanozolol

1987 • 28 citations

Protein S deficiency in pregnancy

1986 • 26 citations

High Levels of Plasma Protein C in Nephrotic Syndrome

1985 • 26 citations

Protein C Deficiency – Response to Danazol and DDAVP

1985 • 26 citations

Studies on immunological assay of vitamin K dependent factors

1986 • 19 citations

Decrease and rapid recovery of protein C after plasma exchange

1986 • 18 citations

Post‐natal Development of Protein C in Full‐term Newborns

1985 • 16 citations

Protein C levels in nephrotic syndrome: Use of a new enzyme‐linked immunoadsorbent assay for protein C antigen

1986 • 15 citations

On the Significance of Antithrombin-III, α2-Macroglobulin, α2-Antiplasmin, Histidine-Rich Glycoprotein, and Protein C in Patients with Acute Myocardial Infarction and Deep Vein Thrombosis

1985 • 11 citations

Defibrination During Warfarin Therapy in a Man with Protein C Deficiency

1985 • 6 citations

Deleted Work

1955 • 0 citations