Protein C, an antithrombotic protein, is reduced in hospitalized patients with intravascular coagulation

Deficiency of protein C in congenital thrombotic disease.

1981 • 1,260 citations

Identification of an endothelial cell cofactor for thrombin-catalyzed activation of protein C.

1981 • 831 citations

A new vitamin K-dependent protein. Purification from bovine plasma and preliminary characterization.

1976 • 634 citations

Human Plasma Protein C

1979 • 511 citations

Preparation and properties of bovine factor VIII (antihemophilic factor)

1980 • 504 citations

Anticoagulant properties of bovine plasma protein C following activation by thrombin

1977 • 495 citations

Mechanism of action of human activated protein C, a thrombin-dependent anticoagulant enzyme

1982 • 385 citations

Generation of fibrinolytic activity by infusion of activated protein C into dogs.

1981 • 303 citations

Proteolytic activation of protein C from bovine plasma

1976 • 211 citations

Deficiency of protein C inhibitor in combined factor V/VIII deficiency disease.

1980 • 207 citations

A new vitamin K-dependent protein. A phospholipid-binding zymogen of a serine esterase.

1976 • 134 citations

Activated protein C inhibits platelet prothrombin-converting activity

1979 • 95 citations

The Defibrination Syndrome

1966 • 91 citations

Relationship of “new” vitamin K-dependent protein C and “old” autoprothrombin II-A

1976 • 74 citations

Inhibitory Effect of Activated Protein C on Activation of Prothrombin by Platelet-Bound Factor Xa

1980 • 63 citations

Purification and some properties of autoprothrombin II-A: An anticoagulant perhaps also related to fibrinolysis

1972 • 59 citations

Inhibitor of human blood coagulation elicited by thrombin.

1972 • 49 citations

ISOLATION, CHARACTERIZATION, AND MECHANISM OF ACTIVATION BY a-THROMBIN

1979 • 24 citations