Oxidative Stress Activates the Human Histidine Decarboxylase Promoter in AGS Gastric Cancer Cells

Antioxidant and redox regulation of gene transcription

1996 • 1,999 citations

Free Radicals as Mediators of Tissue Injury and Disease

1993 • 1,480 citations

The Rho family GTPases RhoA, Racl , and CDC42Hsregulate transcriptional activation by SRF

1995 • 1,280 citations

Epidermal Growth Factor (EGF)-induced Generation of Hydrogen Peroxide

1997 • 1,208 citations

Activation of Mitogen-activated Protein Kinase by H2O2

1996 • 1,202 citations

Role of SAPK/ERK kinase-1 in the stress-activated pathway regulating transcription factor c-Jun

1994 • 978 citations

An essential role for free radicals and derived species in signal transduction

1997 • 909 citations

Inhibition of NIH 3T3 Cell Proliferation by a Mutant ras Protein with Preferential Affinity for GDP

1988 • 757 citations

Reactive oxygen species and programmed cell death

1996 • 745 citations

Regulation and properties of extracellular signal-regulated protein kinases 1 and 2 in vitro.

1993 • 503 citations

Helicobacter pylori stimulates antral mucosal reactive oxygen metabolite production in vivo.

1994 • 415 citations

Increased oxidative DNA damage in Helicobacter pylori-infected human gastric mucosa.

1996 • 358 citations

Role of active oxygen, lipid peroxidation, and antioxidants in the pathogenesis of gastric mucosal injury induced by indomethacin in rats.

1993 • 344 citations

Effect of a dominant inhibitory Ha-ras mutation on neuronal differentiation of PC12 cells.

1990 • 327 citations

Oxygen and the control of gene expression

1994 • 245 citations

Hydrogen peroxide induces complex formation of SHC-Grb2-SOS with receptor tyrosine kinase and activates Ras and extracellular signal-regulated protein kinases group of mitogen-activated protein kinases.

1996 • 238 citations

Oxidative Stress Activates Metal-responsive Transcription Factor-1 Binding Activity

1996 • 237 citations

Sublethal Levels of Oxidant Stress Stimulate Multiple Serine/Threonine Kinases and Suppress Protein Phosphatases in Jurkat T Cells

1995 • 181 citations

A Novel Promoter Sequence Is Involved in the Oxidative Stress-Induced Expression of the Adult T-Cell Leukemia-Derived Factor (ADF)/Human Thioredoxin (Trx) Gene

1996 • 145 citations

Mucosal reactive oxygen metabolite production in duodenal ulcer disease.

1992 • 138 citations

Ascorbic acid may protect against human gastric cancer by scavenging mucosal oxygen radicals

1996 • 137 citations

Hydrolysis of phosphatidylcholine couples Ras to activation of Raf protein kinase during mitogenic signal transduction.

1993 • 135 citations

Reactive oxygen species mediate phorbol ester-regulated tyrosine phosphorylation and phospholipase A2 activation: potentiation by vanadate

1993 • 115 citations

Oxidants stress induces the proto-oncogenes, C-fos and C-myc in mouse epidermal cells.

1990 • 109 citations

Protection of cultured rat gastric cells against oxidant-induced damage by exogenous glutathione

1994 • 105 citations

Reactive oxygen intermediates as second messengers of a general pathogen response.

1996 • 98 citations

Induction of mitogen-activated protein kinase signal transduction pathway during gastric ulcer healing in rats

1998 • 96 citations

Role of Hydroperoxyeicosatetraenoic Acids in Oxidative Stress-induced Activating Protein 1 (AP-1) Activity

1996 • 79 citations

Gastrin and Phorbol 12-Myristate 13-Acetate Regulate the Human Histidine Decarboxylase Promoter through Raf-dependent Activation of Extracellular Signal-regulated Kinase-related Signaling Pathways in Gastric Cancer Cells

1997 • 79 citations

Functional activation of the egr-1 (early growth response-1) gene by hydrogen peroxide

1996 • 70 citations

Expression of a truncated EGF receptor is associated with inhibition of pancreatic cancer cell growth and enhanced sensitivity to cisplatinum

1996 • 55 citations

Gastric injury induced by ethanol and ischemia-reperfusion in the rat

1996 • 54 citations

Histamine and histidine decarboxylase are correlated with mucosal repair in rat small intestine after ischemia-reperfusion.

1992 • 49 citations

The Human Histidine Decarboxylase Promoter Is Regulated by Gastrin and Phorbol 12-Myristate 13-Acetate through a Downstream -Acting Element

1996 • 46 citations

Protective role of intracellular superoxide dismutase against extracellular oxidants in cultured rat gastric cells.

1994 • 35 citations

The regulation of histidine decarboxylase gene expression.

1997 • 34 citations

Mitogenic inhibition by phorbol esters is associated with decreased phosphatidylinositol-3 kinase activation

1996 • 26 citations

The effect of histamine on the oxidative burst of HL60 cells before and after exposure to reactive oxygen species

1995 • 20 citations

Activation of parietal cell by mercaptomethylimidazole

1997 • 18 citations

Protection of cultured rat gastric cells against oxidant stress by iron chelation

1995 • 16 citations

Histamine receptor blockade (H2) versus inhibition of histamine synthesis in stress ulceration in rats

1983 • 13 citations

Histamine Effect on Ornithine Decarboxylase of Rat Intestine in Cases of Ischemia-Reperfusion Compared with Refeeding

1995 • 6 citations

Newly synthesized histamine accelerates ornithine decarboxylase activity in rat intestinal mucosa after ischemia-reperfusion

1995 • 4 citations