Cell-mediated cytotoxicity and the reorientation of effector cell granules towards the target cell are inhibited by the protonophore carbonylcyanide m-chlorophenylhydrazone

Lymphokine-activated killer cell phenomenon. Lysis of natural killer-resistant fresh solid tumor cells by interleukin 2-activated autologous human peripheral blood lymphocytes.

1982 • 2,228 citations

Human chronic myelogenous leukemia cell-line with positive Philadelphia chromosome

1975 • 2,228 citations

In situ detection of mycoplasma contamination in cell cultures by fluorescent Hoechst 33258 stain

1977 • 1,743 citations

Surface IgM-kappa specificity on a Burkitt lymphoma cell in vivo and in derived culture lines.

1968 • 833 citations

Effect of weak bases on the intralysosomal pH in mouse peritoneal macrophages.

1981 • 736 citations

Mechanism of Lymphocyte-Mediated Cytotoxicity

1985 • 602 citations

Isolation of human NK cells by density gradient centrifugation

1980 • 462 citations

Plasma cell immunoglobulin secretion. Arrest is accompanied by alterations the golgi complex

1977 • 404 citations

Uncoupling of Oxidative Phosphorylation by Carbonyl Cyanide Phenylhydrazones. I. Some Characteristics of m-CI-CCP Action on Mitochondria and Chloroplasts

1963 • 338 citations

Polarization of the Golgi apparatus and the microtubule-organizing center within cloned natural killer cells bound to their targets.

1983 • 294 citations

Spatial relationships of microtubule-organizing centers and the contact area of cytotoxic T lymphocytes and target cells.

1982 • 283 citations

Mechanism of Cytotoxicity by Natural Killer (NK) Cells

1986 • 272 citations

Assembly of two types of tubules with putative cytolytic function by cloned natural killer cells

1983 • 253 citations

Isolation of leucocytes from human blood. A two-phase system for removal of red cells with methylcellulose as erythrocyte-aggregating agent.

1968 • 249 citations

Purification and properties of cytoplasmic granules from cytotoxic rat LGL tumors.

1984 • 219 citations

Characterization of the cytolytic reaction mechanism of the human natural killer (NK) lymphocyte: resolution into binding, programming, and killer cell-independent steps.

1982 • 177 citations

Immunobiology of Natural Killer Cells

2019 • 174 citations

Reorientation and fusion of cytotoxic T lymphocyte granules after interaction with target cells as determined by high resolution cinemicrography.

1986 • 166 citations

Pollinator behaviour and natural selection for flower colour in Delphinium nelsonii

1983 • 154 citations

Proteoglycans in cell-mediated cytotoxicity. Identification, localization, and exocytosis of a chondroitin sulfate proteoglycan from human cloned natural killer cells during target cell lysis.

1985 • 149 citations

Monensin and FCCP inhibit the intracellular transport of alphavirus membrane glycoproteins

1980 • 143 citations

Studies on the Mechanism of Lymphocyte-Mediated Cytolysis

1973 • 131 citations

Mechanisms of immune lysis. II. CTL-induced nuclear disintegration of the target begins within minutes of cell contact.

1980 • 119 citations

Cell-mediated killing: A common mechanism?

1986 • 114 citations

Studies on the mechanism of lymphocyte-mediated cytolysis. II. The use of various target cell markers to study cytolytic events.

1973 • 107 citations

The reorientation of the Golgi apparatus and the microtubule-organizing center in the cytotoxic effector cell is a prerequisite in the lysis of bound target cells.

1985 • 106 citations

The cytotoxic activity of human natural killer cells requires an intact secretory apparatus

1981 • 91 citations

Mechanisms of Cell-Mediated Cytotoxicity

1982 • 88 citations

Target-effector cell interaction in the natural killer cell system. V. Energy requirements, membrane integrity, and the possible involvement of lysosomal enzymes.

1980 • 82 citations

ATP-coupled transport of vesicular stomatitis virus G protein. Functional boundaries of secretory compartments.

1986 • 74 citations

Cytolytic and biochemical properties of cytoplasmic granules of murine lymphokine-activated killer cells.

1986 • 70 citations

Direct Analysis of Individual Killer T Cells: Susceptibility of Target Cells to Lysis and Secretion of Hydrolytic Enzymes by CTL

1982 • 51 citations

Sr++-induced inhibition of human natural killer (NK) cell-mediated cytotoxicity.

1982 • 50 citations

Intracellular processing of membrane and secreted immunoglobulin delta-chains.

1984 • 32 citations

The Role of Cytoplasmic Granules in Cytotoxicity by Large Granular Lymphocytes and Cytotoxic T Lymphocytes

1985 • 26 citations

Identification and purification of NK cells with lysosomotropic vital stains: correlation of lysosome content with NK activity.

1985 • 22 citations

Cytolytic T-Cell Granules: Biochemimcal Properties and Functional Specificity

1985 • 13 citations

Oxygen-Reactive Metabolites Are Not Detected at the Effector-Target Interface During Natural Killing

1986 • 10 citations

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