Cathepsin B-like cysteine proteinase-deficient mutants of Leishmania mexicana

Antibodies, a laboratory manual

1989 • 12,929 citations

Peptide synthesis. Part 2. Procedures for solid-phase synthesis using N^α-fluorenylmethoxycarbonylamino-acids on polyamide supports. Synthesis of substance P and of acyl carrier protein 65–74 decapeptide

1981 • 396 citations

The sequence, organization, and expression of the major cysteine protease (cruzain) from Trypanosoma cruzi.

1992 • 294 citations

Development of a stable Leishmania expression vector and application to the study of parasite surface antigen genes.

1990 • 222 citations

Evidence from disruption of the lmcpb gene array of Leishmania mexicana that cysteine proteinases are virulence factors.

1996 • 221 citations

A shuttle vector which facilitates the expression of transfected genes inTrypanosoma cruzi and Leishmania

1992 • 214 citations

Axenic cultivation and characterization ofLeishmania mexicanaamastigote-like forms

1992 • 187 citations

The major cysteine proteinase (cruzipain) from Trypanosoma cruzi is encoded by multiple polymorphic tandemly organized genes located on different chromosomes

1992 • 166 citations

A cysteine proteinase cDNA from Trypanosoma brucei predicts an enzyme with an unusual C‐terminal extension

1989 • 131 citations

The Multiple cpb Cysteine Proteinase Genes ofLeishmania mexicana Encode Isoenzymes That Differ in Their Stage Regulation and Substrate Preferences

1997 • 115 citations

Characterization of a multi‐copy gene for a major stage‐specific cysteine proteinase of Leishmania mexicana

1992 • 106 citations

Parasite proteinases and amino acid metabolism: possibilities for chemotherapeutic exploitation

1997 • 103 citations

Molecular cloning and primary sequence of a cysteine protease expressed by Haemonchus contortus adult worms

1990 • 103 citations

Cytokines: Making the right choice

1992 • 100 citations

Trypanosomiasis and Leishmaniasis: Biology and Control

1998 • 96 citations

Leishmania major:Comparison of the Cathepsin L- and B-like Cysteine Protease Genes with Those of Other Trypanosomatids

1997 • 88 citations

Identification of two distinct cysteine proteinase genes of Leishmania pifanoi axenic amastigotes using the polymerase chain reaction

1993 • 76 citations

A developmentally regulated cysteine proteinase gene of Leishmania mexicana

1992 • 74 citations

Validating targets for antiparasite chemotherapy

1997 • 74 citations

A novel CDC2-related protein kinase from Leishmania mexicana, LmmCRK1, is post-translationally regulated during the life cycle.

1993 • 65 citations

Characterisation of three groups of cysteine proteinases in the amastigotes of Leishmania mexicana mexicana

1990 • 65 citations

Cloning and sequence comparisons of four distinct cysteine proteases expressed by Haemonchus contortus adult worms

1992 • 64 citations

Null mutants for the lmcpa cysteine proteinase gene in Leishmania mexicana

1994 • 63 citations

Families and clans of cysteine peptidases

1996 • 58 citations

The cysteine protease cathepsin B in cancer

1996 • 56 citations

Isolation of lmcpc, a gene encoding a Leishmania mexicana cathepsin-B-like cysteine proteinase

1995 • 42 citations

Induction of a cytotoxic T cell response by co‐injection of a T helper peptide and a cytotoxic T lymphocyte peptide in incomplete Freund's adjuvant (IFA): Further enhancement by pre‐injection of IFA alone

1994 • 39 citations

Parasite cysteine proteinases

1996 • 38 citations

Cathepsin B-like cysteine proteases of Leishmania mexicana

1993 • 37 citations

Kinetics of Entry of Virulent and Avirulent Strains of Leishmania donovani into Macrophages: A Possible Role of Virulence Molecules (gp63 and LPG)

1996 • 36 citations

Proteinases of trypanosomes and Leishmania.

1997 • 30 citations