Formation of Covalent C3b‐Tetanus Toxin Complexes: a Tool for the In Vitro Study of Antigen Presentation

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

The Reliability of Molecular Weight Determinations by Dodecyl Sulfate-Polyacrylamide Gel Electrophoresis

1969 • 20,498 citations

Lounging in a lysosome: the intracellular lifestyle of Coxiella burnetii

2007 • 11,720 citations

“Western Blotting”: Electrophoretic transfer of proteins from sodium dodecyl sulfate-polyacrylamide gels to unmodified nitrocellulose and radiographic detection with antibody and radioiodinated protein A

1981 • 8,657 citations

Protein and cell membrane iodinations with a sparingly soluble chloroamide, 1,3,4,6-tetrachloro-3a,6a-diphenylglycoluril

1978 • 4,673 citations

Spectroscopic Determination of Tryptophan and Tyrosine in Proteins^*

1967 • 3,423 citations

Third component of human complement: purification from plasma and physicochemical characterization

1976 • 523 citations

A unique signature identifies a family of zinc‐dependent metallopeptidases

1989 • 453 citations

Tetanus toxin: primary structure, expression in E. coli, and homology with botulinum toxins.

1986 • 307 citations

The covalent-binding reaction of complement component C3

1981 • 304 citations

Evidence for an Ester Linkage between the Labile Binding Site of C3b and Receptive Surfaces

1979 • 297 citations

A comparison of the properties of two classes, C4A and C4B, of the human complement component C4.

1984 • 296 citations

Clostridial Neurotoxins: Handling and Action at the Cellular and Molecular Level

1986 • 240 citations

The complete nucleotide sequence of tetanus toxin

1986 • 159 citations

C3b covalently bound to IgG demonstrates a reduced rate of inactivation by factors H and I.

1984 • 134 citations

Antigen-bound C3b and C4b enhance antigen-presenting cell function in activation of human T-cell clones.

1988 • 121 citations

Substitution of a single amino acid (aspartic acid for histidine) converts the functional activity of human complement C4B to C4A.

1990 • 109 citations

Characterization of the human complement (c3b) receptor with a fluid phase C3b dimer.

1981 • 104 citations

The role of complement in the induction of antibody responses.

1983 • 96 citations

Suppression of T lymphocyte functions by human C3 fragments. I. Inhibition of human T cell proliferative responses by a kallikrein cleavage fragment of human iC3b.

1983 • 93 citations

The fractionation of rabbit γ-globulin by partition chromatography

1955 • 84 citations

Impaired humoral immune response in complement C3-deficient guinea pigs: absence of secondary antibody response

1986 • 80 citations

The Binding of Activated C3 to Polysaccharides and Immunoglobulins

1978 • 77 citations

Effect of methylamine on the structure and function of the fourth component of human complement, C4.

1980 • 65 citations

Endocytosis of the C3b receptor of complement within coated pits in human polymorphonuclear leukocytes and monocytes.

1983 • 60 citations

Low ionic strength or chemical cross-linking of monomeric C3b increases its binding affinity to the human complement C3b receptor.

1983 • 57 citations

Inhibition of Lymphocyte Blastogenesis by C3c and C3d

1979 • 50 citations

A simple alternative pathway for hemolytic assay of human complement component C3 using methylamine-treated plasma

1983 • 48 citations

Interaction of tetanus toxin with lipid vesicles at low pH. Protection of specific polypeptides against proteolysis.

1985 • 45 citations

Interaction of C3 and C3b with immunoglobulin G

1983 • 44 citations

THE COVALENT BINDING REACTION OF C3 AND C4^a

1983 • 43 citations

Low pH induces a hydrophobic domain in the tetanus toxin molecule

1984 • 43 citations

The Thioester Bond of C3

1990 • 41 citations

Lymphocyte Activation and Differentiation

1988 • 41 citations

Natural release of covalently bound C3b from cell surfaces and the study of this phenomenon in the fluid-phase system.

1984 • 39 citations

Opsonization and Membrane Complement Receptors

1986 • 37 citations

Role of C3b receptors in the enhancement of interleukin-2-dependent T-cell proliferation

1984 • 30 citations

Purification of complement components by hydrophobic affinity chromatography on phenyl—Sepharose

1982 • 30 citations

Biosynthesis and Genetics of C3

1990 • 29 citations

Fluid phase activation of proenzymic C1r purified by affinity chromatography

1982 • 29 citations

Secretion, cleavage and binding of complement component C3 by the human monocytic cell line U937

1989 • 26 citations

Formation of C3-IgG complexes in serum by aggregated IgG and by non-immunoglobulin activators of complement.

1987 • 25 citations

Immunochemistry of Tetanus Toxin The Nitration of Tyrosyl Residues in Tetanus Toxin

1973 • 23 citations

Inefficient Binding of IgM Immune Complexes to Erythrocyte C3b–C4b Receptors (CR1) and Weak Incorporation of C3b–iC3b into the Complexes

1988 • 18 citations

THE THIRD (C3) AND THE FOURTH (C4) COMPONENTS OF COMPLEMENT: LABILE BINDING SITE AND COVALENT BOND FORMATION

1983 • 16 citations

The esterase-like activity of covalently bound human third complement protein

1988 • 16 citations

Binding and catabolism of aggregated immunoglobulins containing C3b by U937 cells.

1986 • 6 citations