Induction of Tumor-Immune Responses and Their Interaction with the Developing Tumor

Functional subclasses of T-lymphocytes bearing different Ly antigens. I. The generation of functionally distinct T-cell subclasses is a differentiative process independent of antigen.

1975 • 1,105 citations

Cancer. A Comprehensive Treatise

1975 • 742 citations

Lymphocyte-Mediated Cytotoxicity And Blocking Serum Activity To Tumor Antigens

1974 • 651 citations

Cytotoxic Effects of Lymphoid Cells in Vitro

1969 • 643 citations

Trans-membrane control of the receptors on normal and tumor cells II. Surface changes associated with transformation and malignancy

1976 • 543 citations

In Vitro Methods in Cell-Mediated Immunity

1971 • 507 citations

GENERATION OF CYTOTOXIC T LYMPHOCYTES IN VITRO

1974 • 488 citations

Cellular Immunity Against Tumor Antigens

1969 • 474 citations

Mechanism of Immunologically Specific Killing of Tumour Cells by Macrophages

1972 • 435 citations

Blocking of cell‐mediated tumor immunity by sera from patients with growing neoplasms

1971 • 423 citations

Macrophage content of tumours in relation to metastatic spread and host immune reaction

1974 • 380 citations

Regualtion of the immune response to tumor antigens. I. Immunosuppressor cells in tumor-bearing hosts.

1976 • 339 citations

Contact-Induced Cytotoxicity by Lymphoid Cells Containing Foreign Isoantigens

1965 • 327 citations

Immunological Enhancement as Studied by Cell Culture Techniques

1970 • 325 citations

Studies on cellular immunity and its serum‐mediated inhibition in moloney‐virus‐induced mouse sarcomas

1969 • 316 citations

Cooperation of Immune Lymphoid Cells with Macrophages in Tumour Immunity

1970 • 315 citations

MACROPHAGES IN SYNGENEIC ANIMAL TUMOURS

1972 • 295 citations

Serum Mediated Inhibition of the Immunological Reactions of the Patient to his Own Tumour: A Possible Role for Circulating Antigen

1972 • 289 citations

Regulation of the immune response to tumor antigens. II. The nature of immunosuppressor cells in tumor-bearing hosts.

1976 • 239 citations

Immunological Aspects Of Chemical Carcinogenesis

1973 • 225 citations

Transplantation methods as a tool for detection of tumor-specific antigens.

1965 • 222 citations

Regulation of the Immune Response to Tumor Antigens

1976 • 207 citations

Ly antigens as markers for functionally distinct subpopulations of thymus-derived lymphocytes of the mouse

1975 • 191 citations

Association of Anergy with an Immunosuppressive Peptide Fraction in the Serum of Patients with Cancer

1974 • 189 citations

Transplantation Methods as a Tool for Detection of Tumor-specific Antigens*

2015 • 183 citations

Inhibition of hepatoma‐immune lymph‐node cell cytotoxicity by tumour‐bearer serum, and solubilized hepatoma antigen

1973 • 157 citations

The Role of Macrophages in Defense Against Neoplastic Disease

1974 • 144 citations

Immunity to murine sarcoma virus-inducted tumors. II. Suppression of T cell-mediated immunity by cells from progressor animals.

1974 • 134 citations

Studies on the role of macrophages in regulation of growth and metastasis of murine chemically induced fibrosarcomas

1975 • 122 citations

On Concomitant Immunity in Tumour-bearing Hamsters

1967 • 120 citations

Homograft Target Cells: Contact Destruction in vitro by Immune Macrophages

1966 • 118 citations

Inhibition of Phytohemagglutinin-Induced <italic>In Vitro</italic> Lymphocyte Transformation by Serum From Patients With Carcinoma

1971 • 117 citations

Counteraction of the blocking of cell‐mediated tumor immunity by inoculation of unblocking sera and splenectomy: immunotherapeutic effects on primary polyoma tumors in rats

1972 • 115 citations

Regulation of the Immune Response to Tumor Antigens

1976 • 114 citations

Regulation of the immune response by subclasses of T lymphocytes. I. Interactions between pre‐killer T cells and regulatory T cells obtained from peripheral lymphoid tissues of mice

1975 • 108 citations

Evolution of Cell-Mediated Immunity in Mice Bearing an Antigenic Tumor. Influence of Tumor Growth and Surgical Removal

1969 • 101 citations

Tumour‐specific antigenicity of aminoazo‐dye‐induced rat hepatomas

1967 • 100 citations

IMMUNOLOGICAL ENHANCEMENT OF TUMOR GROWTH BY SYNGENEIC THYMUS-DERIVED LYMPHOCYTES

1974 • 98 citations

Host Responses Within Solid Tumors. I. Monocytic Effector Cells Within Rat Sarcomas<xref ref-type="fn" rid="fn2">2</xref>

1975 • 96 citations

Cellular and humoral immunity to rat hepatoma‐specific antigens correlated with tumour status

1973 • 91 citations

Immunity to Murine Sarcoma Virus-Induced Tumors

1974 • 90 citations

Immunological Studies on Urinary Bladder Tumors of Rats and Mice

1972 • 89 citations

IN VITRO ASSAY OF TARGET CELL LYSIS BY SENSITIZED LYMPHOCYTES

1971 • 87 citations

Neoantigens on spontaneous and carcinogen‐induced rat tumours defined by in vitro lymphocytotoxicity assays

1974 • 87 citations

Evolution of cell‐mediated antitumor immunity in mice bearing a syngeneic chemically induced tumor. Influence of tumor growth, surgical removal and treatment with irradiated tumor cells

1972 • 86 citations

Evidence for in Vivo Protection against Murine-Sarcoma Virus-Induced Tumors by T Lymphocytes from Immune Animals

1974 • 85 citations

Suppressor Cells in Tumor-Bearing Mice Capable of Nonspecific Blocking of in Vitro Immunization Against Transplant Antigens

1975 • 83 citations

Delayed Hypersensitivity and Transplantation Immunity elicited by Soluble Antigens of Chemically Induced Tumours in Inbred Guinea-pigs

1968 • 82 citations

Detection of Circulating Hepatoma D23 Antigen and Immune Complexes in Tumour Bearer Serum

1973 • 77 citations

Differential stimulation of murine lymphoma growth in vitro by normal and BCG-activated macrophages.

1975 • 75 citations

Concomitant immunity and specific depression of immunity by residual or reinjected syngeneic tumor tissue.

1971 • 73 citations

Host responses within solid tumors: Non‐thymus‐derived specific cytotoxic cells within a murine mammary adenocarcinoma

1975 • 73 citations

Specific Tumor Immunity Induced with Soluble Materials: Restricted Range of Antigen Dose and of Challenge Tumor Load for Immunoprotection

1975 • 71 citations

Requiem for the Nature Conservancy

1972 • 70 citations

Inhibition of in vitro lymphoproliferative responses to tumor‐associated antigens by suppressor cells from rats bearing progressively growing gross leukemia virus‐induced tumors

1975 • 69 citations

Demonstration by colony inhibition methods of cellular and humoral immune reactions to tumour‐specific antigens associated with aminoazo‐dye‐induced rat hepatomas

1971 • 68 citations

Synergism Between Subpopulations of Thymus-Derived Cells Mediating the Proliferative and Effector Phases of the Mixed Lymphocyte Reaction

1973 • 67 citations

BCG Immunotherapy of a Rat Sarcoma

1973 • 66 citations

Suppression of in vitro lymphocyte stimulation in mice bearing primary moloney sarcoma virus-induced tumors

1974 • 64 citations

THE PHAGOCYTOSIS OF TUMOR CELLS

1964 • 64 citations

Cell interactions in adoptive immune rejection of a syngeneic tumor

1974 • 63 citations

Antibodies and Soluble Tumour-specific Antigens in Blood and Lymph of Rats with Chemically Induced Sarcomata

1973 • 57 citations

Anti-θ Serum-indueed Suppression of the Cellular Transfer of Tumour-specific Immunity to a Syngeneic Plasma Cell Tumour

1972 • 56 citations

Tumor-Associated Blocking Factors: Isolation from Sera of Tumor-Bearing Mice

1976 • 56 citations

Requirement of thymus-derived theta-positive lymphocytes for rejection of DNA virus (SV 40) tumors in mice.

1974 • 55 citations

Splenic Regulation of the Clinical Appearance of Small Tumors

1975 • 54 citations

Macrophages in Solid Tumors. I. Immunologically Specific Effector Cells 2

1974 • 54 citations

Role of macrophages in tumour immunity. II. Involvement of a macrophage cytophilic factor during syngeneic tumour growth inhibition.

1972 • 51 citations

Demonstration of Cellular Antigens on Sarcoma Cells by an Indirect<sup>125</sup> I-Labeled Antibody Technique<xref ref-type="fn" rid="FN2">2</xref>

1968 • 50 citations

Serum factors modifying cell mediated immunity to rat hepatoma D23 correlated with tumour growth

1975 • 50 citations

Specific Stimulatory and Cytotoxic Effects of Lymphocytes Sensitized in Vitro to Either Alloantigens or Tumor Antigens

1975 • 50 citations

Blocking of syngeneic effector T cells by soluble tumour antigens

1974 • 49 citations

Soluble tumour‐specific antigen and its relationship to tumour growth

1975 • 46 citations

Cellular basis for the immune response to methylcholanthrene‐induced tumors in mice. Heterogeneity of effector cells

1975 • 44 citations

Sensitization of T Lymphocytes in Vitro by Syngeneic Macrophages Fed with Tumor Antigens

1976 • 44 citations

Humoral Factors Abrogating Cell-Mediated Immunity in the Tumor-Bearing Host

1975 • 44 citations

Studies on a gross‐virus‐induced lymphoma in the rat. I. The cell‐mediated immune response

1974 • 44 citations

Sizes of Conical Volcanoes

1973 • 40 citations

INHIBITION OF TUMOR GROWTH IN SYNGENEIC CHIMERIC MICE MEDIATED BY A DEPLETION OF SUPPRESSOR T CELLS

1975 • 39 citations

The Role of Adherent Cells in the Immune Response

1976 • 39 citations

T cell synergy in mixed lymphocyte culture‐induced cytolysis

1974 • 37 citations

Inhibition of cell‐mediated cytotoxicity to chemically induced rat tumours by soluble tumour and embryo cell extracts

1976 • 37 citations

Antibody-Dependent Cellular Cytotoxicity to a Syngeneic Gross Virus-Induced Lymphoma 2

1974 • 37 citations

Inhibitory T Cells

1975 • 34 citations

The effect of T lymphocyte deficiency on tumor induction and growth

1975 • 33 citations

Effect of Antigen Density on Complement-Mediated Lysis, T-Cell-Mediated Killing, and Antigenic Modulation

1974 • 32 citations

Reversal of Tumor-Mediated Suppression of Immune Reactivity by in Vitro Incubation of Spleen Cells

1974 • 32 citations

Immunogenicity of Rat Hepatoma Membrane Fractions

1973 • 32 citations

Neoantigen Expression in Chemical Carcinogenesis

1975 • 31 citations

Requirement of Thymus-Derived θ-Positive Lymphocytes for Rejection of DNA Virus (SV40) Tumors in Mice

1974 • 30 citations

Specific anti‐tumor responses of cultured immune spleen cells III. Further characterization of cells which synthesize factors with blocking and antiserum‐dependent cellular cytotoxic (ADC) activities

1975 • 30 citations

Specific anti‐tumor responses by cultured immune spleen cells. I. In vitro culture method and initial characterization of factors which block immune cell‐mediated cytotoxicity in vitro

1975 • 30 citations

Analysis of inhibition of lymphocyte cytotoxicity in human colon carcinoma

1975 • 28 citations

Further studies on the ability of regressor sera to block cell‐mediated destruction of rous sarcomas

1974 • 27 citations

Antigenic inhibition of cell-mediated cytotoxicity against tumour cells

1974 • 26 citations

Development of Specific Cell-dependent Antibody During Growth of a Syngeneic Rat Sarcoma

1974 • 26 citations

Effects of sera from tumor-bearing mice on mitogen and allogeneic cell stimulation of normal lymphoid cells.

1975 • 26 citations

The immune response to virally determined tumor associated antigens

1974 • 25 citations

Role of a non-committed accessory cell in the in vivo suppression of a syngeneic tumour by immune lymphocytes.

1975 • 25 citations

Tumour‐specific antibody neutralization of factors in rat hepatoma‐bearer serum which abrogate lymph‐node‐cell cytotoxicity

1974 • 24 citations

Subpopulations of multiparous rat lymph‐node cells cytotoxic for rat tumour cells and capable of suppressing cytotoxicity in vitro

1975 • 22 citations

RESTORATION OF CELL-MEDIATED IMMUNITY TO ANIMALS BLOCKED BY A HUMORAL RESPONSE

1974 • 22 citations

Cell‐mediated cytotoxicity to chemically‐induced rat tumours

1975 • 21 citations

DETECTION OF HEPATOMA-ASSOCIATED EMBRYONIC ANTIGEN IN TUMOUR-BEARER SERUM

1975 • 21 citations

Kinetics of serum factors mediating blocking, unblocking and antibody‐dependent cellular cytotoxicity in hamsters given isografts of para‐7 tumor cells

1976 • 20 citations

Serum Factors in Mammary Neoplasia: Enhancement and Antagonism of Spleen Cell Activity in Vitro Detected by Different Methods of Serum Factor Assay

1974 • 20 citations

Radiation‐killed BCG in the treatment of transplanted rat tumours

1974 • 20 citations

In vitro synthesis of tumor‐specific factors with blocking and antibody‐dependent cellular cytotoxicity (ADC) activities

1975 • 20 citations

Blocking of Spleen Cell Activity against Target Mammary Tumor Cells by Viral Antigens

1975 • 19 citations

ENHANCEMENT OF TUMOR GROWTH IN ALLOGENEIC MICE FOLLOWING IMPAIRMENT OF MACROPHAGE FUNCTION

1975 • 19 citations

Studies on a gross‐virus‐induced lymphoma in the rat. III. Optimisation, specificity and applications of the in vitro immune response

1976 • 18 citations

SUPPRESSOR MECHANISMS IN NEONATALLY ACQUIRED TOLERANCE TO A GROSS VIRUS-INDUCED LYMPHOMA IN RATS

1976 • 18 citations

In Vitro Demonstration of Complement-Dependent Cytotoxic Antibodies to Moloney Sarcoma Cells

1974 • 18 citations

Cell‐mediated cytotoxicity to moloney sarcoma in syngeneic and allogeneic rats

1975 • 17 citations

Serum antibody responses to an ascitic variant of rat hepatoma D23

1975 • 16 citations

Restoration of specific immunity against SV40 tumor‐specific transplantation antigen to lymphoid cells from tumor‐bearing mice

1975 • 15 citations

Blocking Effect of the Migration-Inhibition Reaction by Sera From Immunized Syngeneic Mice and by Sera From Plasmacytoma-Bearing BALB/c Mice. Detection of Free, Circulating Tumor Antigen

1974 • 14 citations

CELL‐MEDIATED IMMUNITY TO MOUSE TUMORS: SOME RECENT FINDINGS*

1976 • 14 citations

The Specificity of Effector T Cells Activated by Tumours Induced by Murine Oncornaviruses

1976 • 13 citations

Effect of BCG on cell-mediated cytotoxicity and serum blocking factor during growth of rat hepatoma

1976 • 12 citations

Early onset of serum blocking in a murine melanoma model

1975 • 10 citations

Humoral Immune Responses to Tumor-Specific Antigens in Strain-2 Guinea Pigs

1974 • 10 citations

A microassay for humoral cytotoxicity demonstrating sublethal effects of antibody

1974 • 10 citations

Recognition of the Individuality of Tumour Strain by Sensitized Peritoneal Lymphoid Cells

1967 • 9 citations

Rejection of tumor cells in vitro: A T‐cell‐mediated reaction

1975 • 8 citations

Activation of “eclipsed” lymphoid cells from advanced tumor‐bearing mice through adoptive transfer to sublethally irradiated syngeneic hosts

1975 • 7 citations

Serum factor levels during the growth of rat hepatoma nodules in the lungs

1976 • 6 citations

Molecular approaches to immunology : proceedings of the Miami winter symposia, January 13-17, 1975

1975 • 1 citations