Humoral Factors Abrogating Cell-Mediated Immunity in the Tumor-Bearing Host

Cancer. A Comprehensive Treatise

1975 • 742 citations

Suggestive Evidence That the “Blocking Antibodies” of Tumor-Bearing Individuals May Be Antigen-Antibody Complexes

1971 • 691 citations

Lymphocyte-Mediated Cytotoxicity And Blocking Serum Activity To Tumor Antigens

1974 • 651 citations

Progress in immunology

1968 • 577 citations

Immunology of Experimental Tumors

1964 • 487 citations

Cellular Immunity Against Tumor Antigens

1969 • 474 citations

Regualtion of the immune response to tumor antigens. I. Immunosuppressor cells in tumor-bearing hosts.

1976 • 339 citations

Immunological Enhancement as Studied by Cell Culture Techniques

1970 • 325 citations

Studies on cellular immunity and its serum‐mediated inhibition in moloney‐virus‐induced mouse sarcomas

1969 • 316 citations

Serum Mediated Inhibition of the Immunological Reactions of the Patient to his Own Tumour: A Possible Role for Circulating Antigen

1972 • 289 citations

Regulation of the immune response to tumor antigens. II. The nature of immunosuppressor cells in tumor-bearing hosts.

1976 • 239 citations

Immunological Aspects Of Chemical Carcinogenesis

1973 • 225 citations

Transplantation methods as a tool for detection of tumor-specific antigens.

1965 • 222 citations

Colony inhibition studies on blocking and non‐blocking serum effects on cellular immunity to moloney sarcomas

1970 • 197 citations

Inhibition of Proliferation of Lymphoma Cells and T Lymphocytes by Suppressor Cells from Spleens of Tumor-Bearing Mice

1975 • 190 citations

Elution of “blocking factors” from human tumors, capable of abrogating tumor‐cell destruction by specifically immune lymphocytes

1972 • 190 citations

Transplantation Methods as a Tool for Detection of Tumor-specific Antigens*

2015 • 183 citations

Cancer, Differentiation and Embryonic Antigens: Some Central Problems

1974 • 183 citations

Serum mediated inhibition of cellular immunity to methylcholanthrene-induced murine sarcomas

1970 • 180 citations

Serum factors in tumor‐free patients cancelling the blocking of cell‐mediated tumor immunity

1971 • 164 citations

Inhibition of hepatoma‐immune lymph‐node cell cytotoxicity by tumour‐bearer serum, and solubilized hepatoma antigen

1973 • 157 citations

Sequential studies on cell‐mediated tumor immunity and blocking serum activity in ten patients with malignant melanoma

1973 • 148 citations

Evidence for an Immunological Reaction of the Host Directed Against Its Own Actively Growing Primary Tumor<xref ref-type="fn" rid="FN1">2</xref>

1966 • 148 citations

Specific killing of tumor cells In vitro in the presence of normal lymphoid cells and sera from hosts immune to the tumor antigens

1972 • 142 citations

Immunity to murine sarcoma virus-inducted tumors. II. Suppression of T cell-mediated immunity by cells from progressor animals.

1974 • 134 citations

Circulating immune complexes in human neuroblastoma: Direct assay and role in blocking specific cellular immunity

1974 • 126 citations

On Concomitant Immunity in Tumour-bearing Hamsters

1967 • 120 citations

Counteraction of the blocking of cell‐mediated tumor immunity by inoculation of unblocking sera and splenectomy: immunotherapeutic effects on primary polyoma tumors in rats

1972 • 115 citations

Facilitation of polyoma tumor growth in rats by blocking sera and tumor eluate

1972 • 100 citations

Influence of Tumor Size and Surgical Resection on Cell-Mediated Immunity in Mice2

1974 • 95 citations

The effect of tumor size on concomitant tumor immunity.

1973 • 93 citations

Immunosuppressor T Cells in Tumor Bearing Hosts

1975 • 92 citations

Cellular and humoral immunity to rat hepatoma‐specific antigens correlated with tumour status

1973 • 91 citations

Embryonic antigen expression in chemically induced rat hepatomas and sarcomas

1972 • 90 citations

“Unblocking” Serum Activity in vitro in the Polyoma System may Correlate with Antitumour Effects of Antiserum in vivo

1971 • 89 citations

Carcinoembryonic Antigen: Characterization and Clinical Applications

1974 • 87 citations

Neoantigens on spontaneous and carcinogen‐induced rat tumours defined by in vitro lymphocytotoxicity assays

1974 • 87 citations

Evolution of cell‐mediated antitumor immunity in mice bearing a syngeneic chemically induced tumor. Influence of tumor growth, surgical removal and treatment with irradiated tumor cells

1972 • 86 citations

Detection of Circulating Hepatoma D23 Antigen and Immune Complexes in Tumour Bearer Serum

1973 • 77 citations

Alpha‐fetoprotein: Immunochemical Purification and Chemical Properties. Expression in Normal State and in Malignant and non‐Malignant Liver Disease

1974 • 76 citations

Concomitant immunity and specific depression of immunity by residual or reinjected syngeneic tumor tissue.

1971 • 73 citations

Requiem for the Nature Conservancy

1972 • 70 citations

Suggestive evidence for in vivo binding of specific antitumor antibodies of human melanomas.

1975 • 69 citations

Demonstration by colony inhibition methods of cellular and humoral immune reactions to tumour‐specific antigens associated with aminoazo‐dye‐induced rat hepatomas

1971 • 68 citations

Influence of tumor antigen on maintenance versus depression of tumor-specific immunity.

1973 • 67 citations

BCG Immunotherapy of a Rat Sarcoma

1973 • 66 citations

Nonspecific and specific immuno-suppression in tumour-bearing mice by soluble immune complexes

1975 • 64 citations

Defects in cell‐mediated immunity during growth of a syngeneic simian virus‐induced tumor

1975 • 62 citations

Tumor-associated immunoglobulins. enhancement of syngeneic tumors by igg2-containing tumor eluates

1972 • 62 citations

Active immunotherapy as an adjunct to chemotherapy in the treatment of disseminated malignant melanoma: a pilot study

1975 • 61 citations

Evolution of Cell-Mediated Immunity in Mice Bearing Tumors Produced by a Mammary Carcinoma Cell Line. Influence of Tumor Growth, Surgical Removal, and Treatment With Irradiated Tumor Cells<xref ref-type="fn" rid="FN2">2</xref>

1971 • 57 citations

Radioimmunoassay of Tumour Specific Transplantation Antigen of a Chemically Induced Rat Sarcoma: Circulating Soluble Tumour Antigen in Tumour Bearers

1973 • 57 citations

Fractionation of plasma membrane‐associated tumour‐specific antigen from an aminoazo dye‐induced rat hepatoma

1973 • 57 citations

Antibodies and Soluble Tumour-specific Antigens in Blood and Lymph of Rats with Chemically Induced Sarcomata

1973 • 57 citations

Blocking and unblocking of cell-mediated anti-tumor immunity in mice, as detected by the leucocyte adherence inhibition test

1974 • 55 citations

Embryonic Antigen Expression on Experimental Rat Tumours

1974 • 55 citations

Macrophage migration inhibition with mouse tumor antigens: Properties of serum and peritoneal cells during tumor growth and after tumor loss

1972 • 53 citations

Cell-mediated immune reactions to tumor antigens with particular emphasis on immunity to human neoplasms

1974 • 51 citations

A Factor Preventing the Development of Lung Metastases in Rats with Sarcomas

1973 • 51 citations

Cytotoxic effect of lymphocytes from pregnant mice on cultivated tumor cells. I. Specificity, nature of effector cells and blocking by serum

1975 • 51 citations

Serum factors modifying cell mediated immunity to rat hepatoma D23 correlated with tumour growth

1975 • 50 citations

The Biological Significance of Tumor-Bound Immunoglobulins

1973 • 50 citations

Blocking of syngeneic effector T cells by soluble tumour antigens

1974 • 49 citations

Association of Tumor and Histocompatibility Antigens in Sera of Lymphoma-Bearing Mice

1973 • 49 citations

Tumor‐associated immunogolobulins. The elution of IgG2 from mouse tumors

1970 • 48 citations

Circulating Antigen-Antibody Complex Associated With Epstein-Barr Virus in Recurrent Burkitt's Lymphoma2

1973 • 47 citations

Specific desensitization of resistance against a syngeneic methylcholanthrene-induced sarcoma in C3Hf mice.

1972 • 47 citations

Soluble tumour‐specific antigen and its relationship to tumour growth

1975 • 46 citations

Specific “arming” of normal lymph‐node cells by sera from tumor‐bearing mice

1973 • 45 citations

Studies on a gross‐virus‐induced lymphoma in the rat. I. The cell‐mediated immune response

1974 • 44 citations

Significance of serum factors modifying cellular immune responses to growing tumours.

1973 • 41 citations

Circulating tumor antigens versus immune serum factors in depressed concomitant immunity.

1974 • 39 citations

In vitro „education” on autologous human sarcoma generates non-specific killer cells

1975 • 38 citations

In vitro immunization to cultured human tumor cells.

1974 • 36 citations

In vitro studies on cell‐mediated immunity following surgery in mice sensitized to syngeneic mammary tumors

1972 • 36 citations

Studies on immunity to autochthonous mouse tumors.

1969 • 34 citations

Sensitisation of lymphocytes in vitro against human melanoma-associated antigens

1974 • 34 citations

Regression of polyoma tumor metastasis by combined unblocking and bcg treatment‐correlation with induced alterations in tumor immunity status

1973 • 34 citations

The development and specific suppression of concomitant immunity in two syngeneic tumour‐host systems

1973 • 33 citations

Study of thein vivo fixation of antibodies on tumors provoked in hamsters by injection of SV40-transformed cells (TSV5Cl2)

1971 • 32 citations

Reversal of Tumor-Mediated Suppression of Immune Reactivity by in Vitro Incubation of Spleen Cells

1974 • 32 citations

Immunogenicity of Rat Hepatoma Membrane Fractions

1973 • 32 citations

Kinetics of the anti-tumor delayed hypersensitivity response in mice with progressively growing tumors: Stimulation followed by specific suppression

1974 • 31 citations

Neoantigen Expression in Chemical Carcinogenesis

1975 • 31 citations

Immunity to murine sarcoma virus induced tumours. IV. Direct cellular cytolysis of 51Cr labelled target cells in vitro and analysis of blocking factors which modulate cytotoxicity

1975 • 30 citations

Specific anti‐tumor responses by cultured immune spleen cells. I. In vitro culture method and initial characterization of factors which block immune cell‐mediated cytotoxicity in vitro

1975 • 30 citations

Differentiation Between the Embryonic and Tumour Specific Antigens on Chemically Induced Rat Tumours

1974 • 29 citations

Serum effects on cell‐mediated destruction of rous sarcomas

1973 • 29 citations

Cell Surface Antigen Movement: Induction in Hepatoma Cells by Antitumor Antibody

1973 • 29 citations

Tumor-associated immunoglobulins.

1971 • 28 citations

In Vitro Studies on Mechanism of the “Eclipse” of Cell-Mediated Immunity in Mice Bearing Advanced Tumors2

1973 • 28 citations

Analysis of inhibition of lymphocyte cytotoxicity in human colon carcinoma

1975 • 28 citations

Tumor-Associated Specificity of Serum-Mediated Inhibition of Lymphocyte Stimulation by Autochthonous Human Tumors2

1973 • 28 citations

Further studies on the ability of regressor sera to block cell‐mediated destruction of rous sarcomas

1974 • 27 citations

IgG associated with microsomes from autochthonous hepatomas and normal liver of rats.

1967 • 26 citations

Antigenic inhibition of cell-mediated cytotoxicity against tumour cells

1974 • 26 citations

Development of Specific Cell-dependent Antibody During Growth of a Syngeneic Rat Sarcoma

1974 • 26 citations

ESCAPE FROM ISOANTISERUM INHIBITION OF LYMPHOCYTE-MEDIATED CYTOTOXICITY

1973 • 25 citations

Cytotoxic effect of lymphocytes from pregnant mice on cultivated tumor cells. II. Blocking and unblocking of cytotoxicity

1975 • 25 citations

Studies on a gross‐virus‐induced lymphoma in the rat. II. The role of cell‐membrane‐associated and serum p30 antigen in the antibody and cell‐mediated response

1975 • 25 citations

Tumour‐specific antibody neutralization of factors in rat hepatoma‐bearer serum which abrogate lymph‐node‐cell cytotoxicity

1974 • 24 citations

Characterization of Cytotoxic Effector Cells in the Mouse Mammary Tumor System

1975 • 22 citations

Cell‐mediated cytotoxicity to chemically‐induced rat tumours

1975 • 21 citations

DETECTION OF HEPATOMA-ASSOCIATED EMBRYONIC ANTIGEN IN TUMOUR-BEARER SERUM

1975 • 21 citations

Mechanism of blocking by hyperimmune serum of lymphocyte-mediated cytolysis of allogeneic tumor cells.

1973 • 21 citations

Detection of cytotoxic T lymphocytes in the EL4 mouse leukemia system: Increased activity of immune spleen and peritoneal cells following preincubation and cell fractionation procedures

1974 • 21 citations

THE EXPRESSION OF A PHASE-SPECIFIC FOETAL ANTIGEN ON RAT EMBRYO CELLS

1974 • 21 citations

Generation of Non-Complement-Fixing, Blocking Factors by Lysosomal Extract Treatment of Cytotoxic Anti-Tumor Antibodies

1974 • 21 citations

Inhibition of rat lymph node cell cytotoxicity by hepatoma-associated embryonic antigen

1974 • 20 citations

Serum Factors in Mammary Neoplasia: Enhancement and Antagonism of Spleen Cell Activity in Vitro Detected by Different Methods of Serum Factor Assay

1974 • 20 citations

Blocking of Spleen Cell Activity against Target Mammary Tumor Cells by Viral Antigens

1975 • 19 citations

In Vitro Studies on the Cellular Immune Response of Tumor-Bearing Mice to SV40-Transformed Cells

1975 • 17 citations

A method for elution of immunoglobulin from the surface of living cells.

1971 • 17 citations

Serum antibody responses to an ascitic variant of rat hepatoma D23

1975 • 16 citations

Interaction of Isoantibody and Cytotoxic Lymphocytes with Allogeneic Tumor Cells

1974 • 16 citations

Refractoriness of lymph-node cells from tumour-bearing animals

1975 • 16 citations

Cell‐mediated immunity to moloney sarcoma virus in mice. I. Analysis of antigens responsible for lymphocyte stimulation in regressor mice

1975 • 15 citations

Blocking Effect of the Migration-Inhibition Reaction by Sera From Immunized Syngeneic Mice and by Sera From Plasmacytoma-Bearing BALB/c Mice. Detection of Free, Circulating Tumor Antigen

1974 • 14 citations

Tumor-Associated Antigen (TAA) and Anti-TAA Antibodies in the Serum of BALB/c Mice With Plasmacytomas

1974 • 13 citations

Immunologic Response to Human Sarcomas: Relation of Antitumor Antibody to the Clinical Course

1971 • 13 citations

Early onset of serum blocking in a murine melanoma model

1975 • 10 citations

Embryonic Antigen Expression on 2-Acetylaminofluorene Induced and Spontaneously Arising Rat Tumours

1974 • 10 citations

Humoral Immune Responses to Tumor-Specific Antigens in Strain-2 Guinea Pigs

1974 • 10 citations

Tumour‐associated transplantation antigen in sera of rats with large RSV‐induced sarcomas

1975 • 8 citations

Control of tumor growth in mice by thoracic duct drainage: Relationship to blocking factor in lymph

1974 • 8 citations

Effect of solubilized membrane antigens and tumour bearer serum on tumour growth in syngeneic hosts

1974 • 8 citations

Temperature control of lymphocyte-mediated cytotoxicity in vitro.

1973 • 7 citations

Tumour-associated antigen in the serum of rats with large Rous sarcoma virus-induced tumours.

1973 • 6 citations

Blocking of a cellular immune reaction to malignant melanoma by immunoglobulin from tumor-bearing animals.

1973 • 4 citations

Proceedings: Tumour antigen in human cancer patients' sera

1975 • 2 citations