New insights into the mechanism for clearance of apoptotic cells

Exposure of phosphatidylserine on the surface of apoptotic lymphocytes triggers specific recognition and removal by macrophages.

1992 • 3,279 citations

Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF.

1998 • 3,085 citations

A receptor for phosphatidylserine-specific clearance of apoptotic cells

2000 • 1,480 citations

Pathophysiologic Implications of Membrane Phospholipid Asymmetry in Blood Cells

1997 • 1,321 citations

Thrombospondin cooperates with CD36 and the vitronectin receptor in macrophage recognition of neutrophils undergoing apoptosis.

1992 • 818 citations

The role of phosphatidylserine in recognition of apoptotic cells by phagocytes

1998 • 724 citations

Human CD14 mediates recognition and phagocytosis of apoptotic cells

1998 • 685 citations

Different populations of macrophages use either the vitronectin receptor or the phosphatidylserine receptor to recognize and remove apoptotic cells.

1992 • 605 citations

CD36 is required for phagocytosis of apoptotic cells by human macrophages that use either a phosphatidylserine receptor or the vitronectin receptor (alpha v beta 3).

1998 • 397 citations

CD36 Is Required for Phagocytosis of Apoptotic Cells by Human Macrophages That Use Either a Phosphatidylserine Receptor or the Vitronectin Receptor (αvβ3)

1998 • 321 citations

The ATP binding cassette transporter ABC1, is required for the engulfment of corpses generated by apoptotic cell death.

1996 • 294 citations

Initial characterization of monoclonal antibodies against human monocytes.

1980 • 276 citations

Cell Adhesion to Phosphatidylserine Mediated by a Product of Growth Arrest-specific Gene 6

1997 • 244 citations

Promotion of the Uptake of PS Liposomes and Apoptotic Cells by a Product of Growth Arrest-Specific Gene, gas6

2000 • 224 citations

CD14-dependent clearance of apoptotic cells: relevance to the immune system

2000 • 191 citations

Phagocytosis of apoptotic bodies by liver endothelial cells

1995 • 157 citations

Engulfment of apoptotic cells involves the redistribution of membrane phosphatidylserine on phagocyte and prey

1999 • 157 citations

Recognition of oxidatively damaged erythrocytes by a macrophage receptor with specificity for oxidized low density lipoprotein.

1994 • 151 citations

Recognition of apoptotic cells by human macrophages: inhibition by a monocyte/macrophage‐specific monoclonal antibody

1994 • 118 citations

Phosphatidylinositides Bind to Plasma Membrane CD14 and Can Prevent Monocyte Activation by Bacterial Lipopolysaccharide

1998 • 94 citations

Essential Role of Phosphatidylserine Externalization in Apoptosing Cell Phagocytosis by Macrophages

1998 • 84 citations

CD14 is a component of multiple recognition systems used by macrophages to phagocytose apoptotic lymphocytes

1999 • 83 citations