A Mutation in the MSH6 Subunit of the Saccharomyces cerevisiae MSH2-MSH6 Complex Disrupts Mismatch Recognition

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

Molecular Cloning: A Laboratory Manual

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Molecular Cloning. A Laboratory Manual

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1979 • 7,824 citations

Site-directed mutagenesis by overlap extension using the polymerase chain reaction

1989 • 7,496 citations

Methods in Yeast Genetics

1988 • 4,905 citations

Multifunctional yeast high-copy-number shuttle vectors

1992 • 1,656 citations

MISMATCH REPAIR IN REPLICATION FIDELITY, GENETIC RECOMBINATION, AND CANCER BIOLOGY

1996 • 1,485 citations

The distribution of the numbers of mutants in bacterial populations

1949 • 1,471 citations

Construction of a set of convenient saccharomyces cerevisiae strains that are isogenic to S288C

1995 • 945 citations

Isolation of an hMSH2-p160 Heterodimer That Restores DNA Mismatch Repair to Tumor Cells

1995 • 599 citations

Biochemistry and genetics of eukaryotic mismatch repair.

1996 • 598 citations

Redundancy of Saccharomyces cerevisiae MSH3 and MSH6 in MSH2-dependent mismatch repair.

1996 • 576 citations

DNA Mismatch Correction in a Defined System

1989 • 551 citations

Applications of high efficiency lithium acetate transformation of intact yeast cells using single‐stranded nucleic acids as carrier

1991 • 433 citations

The Human Mismatch Recognition Complex hMSH2-hMSH6 Functions as a Novel Molecular Switch

1997 • 357 citations

Characterization of insertion mutations in the Saccharomyces cerevisiae MSH1 and MSH2 genes: evidence for separate mitochondrial and nuclear functions.

1992 • 353 citations

Escherichia coli mutS-encoded protein binds to mismatched DNA base pairs.

1986 • 353 citations

MutS mediates heteroduplex loop formation by a translocation mechanism

1997 • 325 citations

Initiation of methyl-directed mismatch repair.

1992 • 313 citations

Use of lacZ fusions to delimit regulatory elements of the inducible divergent GAL1-GAL10 promoter in Saccharomyces cerevisiae.

1984 • 310 citations

Isolation and Characterization of the Escherichia coli mutL Gene Product

1989 • 298 citations

Instability of simple sequence DNA in Saccharomyces cerevisiae.

1992 • 240 citations

recA protein-catalyzed strand assimilation: stimulation by Escherichia coli single-stranded DNA-binding protein.

1980 • 238 citations

Isolation and characterization of the Escherichia coli mutH gene product.

1987 • 220 citations

Nucleotide-promoted Release of hMutSα from Heteroduplex DNA Is Consistent with an ATP-dependent Translocation Mechanism

1998 • 190 citations

Requirement of the Yeast MSH3 and MSH6 Genes for MSH2-dependent Genomic Stability

1996 • 187 citations

hMSH2 and hMSH6 play distinct roles in mismatch binding and contribute differently to the ATPase activity of hMutSalpha

1998 • 173 citations

The Saccharomyces cerevisiae Msh2 and Msh6 Proteins Form a Complex That Specifically Binds to Duplex Oligonucleotides Containing Mismatched DNA Base Pairs

1996 • 168 citations

Altering the conserved nucleotide binding motif in the Salmonella typhimurium MutS mismatch repair protein affects both its ATPase and mismatch binding activities.

1991 • 164 citations

Binding of insertion/deletion DNA mismatches by the heterodimer of yeast mismatch repair proteins MSH2 and MSH3

1996 • 163 citations

Purification and characterization of MSH1, a yeast mitochondrial protein that binds to DNA mismatches.

1994 • 152 citations

Mutations in the MSH3 gene preferentially lead to deletions within tracts of simple repetitive DNA in Saccharomyces cerevisiae.

1995 • 147 citations

Genetic and Biochemical Analysis of Msh2p-Msh6p: Role of ATP Hydrolysis and Msh2p-Msh6p Subunit Interactions in Mismatch Base Pair Recognition

1997 • 129 citations

ATP-dependent Assembly of a Ternary Complex Consisting of a DNA Mismatch and the Yeast MSH2-MSH6 and MLH1-PMS1 Protein Complexes

1998 • 126 citations

The Saccharomyces cerevisiae Msh2 protein specifically binds to duplex oligonucleotides containing mismatched DNA base pairs and insertions.

1995 • 106 citations

MSH6, a Saccharomyces cerevisiae protein that binds to mismatches as a heterodimer with MSH2

1996 • 101 citations

Photocross-linking of the NH2-terminal Region of Taq MutS Protein to the Major Groove of a Heteroduplex DNA

1997 • 100 citations

Saccharomyces cerevisiaeMsh2p and Msh6p ATPase Activities Are Both Required during Mismatch Repair

1998 • 90 citations

Enhancement of MSH2–MSH3-mediated mismatch recognition by the yeast MLH1–PMS1 complex

1997 • 82 citations

The effect of DNA mismatches on the ATPase activity of MSH1, a protein in yeast mitochondria that recognizes DNA mismatches.

1994 • 69 citations