Interaction of Nascent ApoE2, ApoE3, and ApoE4 Isoforms Expressed in Mammalian Cells with Amyloid Peptide β (1−40). Relevance to Alzheimer's Disease

Correlative Memory Deficits, Aβ Elevation, and Amyloid Plaques in Transgenic Mice

1996 • 4,118 citations

Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein

1995 • 2,456 citations

Apolipoprotein E polymorphism and atherosclerosis.

1988 • 2,007 citations

Isolation and quantification of soluble Alzheimer's β-peptide from biological fluids

1992 • 1,701 citations

Apolipoprotein E: A pathological chaperone protein in patients with cerebral and systemic amyloid

1992 • 802 citations

Amyloid β-Protein and the Genetics of Alzheimer's Disease

1996 • 794 citations

A role for apolipoprotein E, apolipoprotein A-I, and low density lipoprotein receptors in cholesterol transport during regeneration and remyelination of the rat sciatic nerve.

1989 • 532 citations

Modulation of plasma triglyceride levels by apoE phenotype: a meta-analysis.

1992 • 453 citations

Opposing effects of apolipoproteins E and C on lipoprotein binding to low density lipoprotein receptor-related protein.

1990 • 451 citations

Apolipoprotein E associates with beta amyloid peptide of Alzheimer's disease to form novel monofibrils. Isoform apoE4 associates more efficiently than apoE3.

1994 • 407 citations

Pinopsin is a chicken pineal photoreceptive molecule

1994 • 341 citations

Human apolipoprotein E: the Alzheimer's disease connection

1996 • 325 citations

Plastic Neuronal Remodeling Is Impaired in Patients with Alzheimer’s Disease Carrying Apolipoprotein ε4 Allele

1997 • 321 citations

Binding of arginine-rich (E) apoprotein after recombination with phospholipid vesicles to the low density lipoprotein receptors of fibroblasts.

1979 • 303 citations

Neuropathological changes in scrapie and Alzheimer's disease are associated with increased expression of apolipoprotein E and cathepsin D in astrocytes

1991 • 297 citations

The cerebrospinal-fluid soluble form of Alzheimer's amyloid β is complexed to SP-40,40 (apolipoprotein J), an inhibitor of the complement membrane-attack complex

1993 • 295 citations

Fibrillogenesis in Alzheimer's disease of amyloid β peptides and apolipoprotein E

1995 • 255 citations

Effects of apolipoprotein E, beta-very low density lipoproteins, and cholesterol on the extension of neurites by rabbit dorsal root ganglion neurons in vitro.

1992 • 199 citations

Synthesis, intracellular processing, and signal peptide of human apolipoprotein E.

1984 • 188 citations

Cell surface receptor binding of phospholipid . protein complexes containing different ratios of receptor-active and -inactive E apoprotein.

1980 • 171 citations

Identification of the disulfide-linked homodimer of apolipoprotein E3 in plasma. Impact on receptor binding activity

1991 • 99 citations

Isoform-specific interactions of apolipoprotein E with the microtubule-associated protein MAP2c: implications for Alzheimer's disease

1994 • 81 citations

Alzheimer amyloid-beta peptide forms denaturant-resistant complex with type epsilon 3 but not type epsilon 4 isoform of native apolipoprotein E.

1996 • 71 citations

Lack of association between apolipoprotein E allele ɛ4 and sporadic Alzheimer's disease

1994 • 57 citations

Intracellular modifications of human apolipoprotein E.

1986 • 56 citations

The very low density lipoprotein receptor

1993 • 49 citations

Alzheimer Amyloid-β Peptide Forms Denaturant-Resistant Complex with Type ε3 but Not Type ε4 Isoform of Native Apolipoprotein E

1996 • 45 citations

Conformation of apolipoprotein E in lipoproteins.

1993 • 38 citations

Regulation of the human ApoA-II gene by the synergistic action of factors binding to the proximal and distal regulatory elements.

1991 • 30 citations