Calcium-dependent Threonine Phosphorylation of Nonmuscle Myosin in Stimulated RBL-2H3 Mast Cells

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase

1988 • 6,107 citations

Differential activation of CREB by Ca2+/calmodulin-dependent protein kinases type II and type IV involves phosphorylation of a site that negatively regulates activity.

1994 • 718 citations

Mast cells as a source of multifunctional cytokines

1990 • 708 citations

The Ca2+–calmodulin-dependent protein kinase cascade

1999 • 502 citations

Calcium mobilization via sphingosine kinase in signalling by the FcɛRI antigen receptor

1996 • 374 citations

Ca(2+)-dependent and Ca(2+)-independent isozymes of protein kinase C mediate exocytosis in antigen-stimulated rat basophilic RBL-2H3 cells. Reconstitution of secretory responses with Ca2+ and purified isozymes in washed permeabilized cells.

1993 • 369 citations

Nonmuscle myosin II-B is required for normal development of the mouse heart

1997 • 304 citations

N,N-Dimethylsphingosine Is a Potent Competitive Inhibitor of Sphingosine Kinase but Not of Protein Kinase C: Modulation of Cellular Levels of Sphingosine 1-Phosphate and Ceramide

1998 • 229 citations

Rac regulates phosphorylation of the myosin-II heavy chain, actinomyosin disassembly and cell spreading

1999 • 214 citations

Protein kinase C regulation of the receptor-coupled calcium signal in histamine-secreting rat basophilic leukaemia cells

1985 • 186 citations

Phosphorylation of Rat Serine 105 or Mouse Threonine 217 in C/EBPβ Is Required for Hepatocyte Proliferation Induced by TGFα

1999 • 165 citations

Antigen-induced Secretion of Histamine and the Phosphorylation of Myosin by Protein Kinase C in Rat Basophilic Leukemia Cells

1989 • 161 citations

Reorganisation of peripheral actin filaments as a prelude to exocytosis

1987 • 144 citations

Phosphopeptide mapping and phosphoamino acid analysis by electrophoresis and chromatography on thin‐layer cellulose plates

1994 • 138 citations

Calcium/Calmodulin-dependent Phosphorylation and Activation of Human Cdc25-C at the G2/M Phase Transition in HeLa Cells

1999 • 137 citations

Definition of Optimal Substrate Recognition Motifs of Ca2+-Calmodulin-dependent Protein Kinases IV and II Reveals Shared and Distinctive Features

1998 • 134 citations

Metastasis-associated Mts1 (S100A4) Protein Modulates Protein Kinase C Phosphorylation of the Heavy Chain of Nonmuscle Myosin

1998 • 130 citations

CaM kinase II: a protein kinase with extraordinary talents germane to insulin exocytosis.

1999 • 126 citations

Cloning of the cDNA encoding human nonmuscle myosin heavy chain-B and analysis of human tissues with isoform-specific antibodies

1995 • 121 citations

Human nonmuscle myosin heavy chain mRNA: generation of diversity through alternative polyadenylylation.

1990 • 121 citations

Two Nonmuscle Myosin II Heavy Chain Isoforms Expressed in Rabbit Brains: Filament Forming Properties, the Effects of Phosphorylation by Protein Kinase C and Casein Kinase II, and Location of the Phosphorylation Sites

1998 • 102 citations

The role of Ca2+/calmodulin-dependent protein kinases within the nucleus

1998 • 99 citations

Synergistic signals in the mechanism of antigen-induced exocytosis in 2H3 cells: evidence for an unidentified signal required for histamine release.

1987 • 90 citations

Effect of Mts1 on the Structure and Activity of Nonmuscle Myosin II

1997 • 85 citations

Role of the COOH-terminal nonhelical tailpiece in the assembly of a vertebrate nonmuscle myosin rod.

1992 • 84 citations

Carbachol induces secretion in a mast cell line (RBL‐2H3) transfected with the ml muscarinic receptor gene

1991 • 70 citations

Modulation of mts1 expression in mouse and human normal and tumor cells

1994 • 68 citations

Antigen and carbachol mobilize calcium by similar mechanisms in a transfected mast cell line (RBL-2H3 cells) that expresses ml muscarinic receptors.

1993 • 65 citations

Rho Controls Cortical F-actin Disassembly in Addition to, but Independently of, Secretion in Mast Cells

1999 • 65 citations

Solubility‐determining domain of smooth muscle myosin rod

1986 • 35 citations

Cloning of the cDNA encoding rat myosin heavy chain-A and evidence for the absence of myosin heavy chain-B in cultured rat mast (RBL-2H3) cells

1996 • 33 citations

Cleavage of a smooth muscle myosin heavy chain near its C terminus by alpha-chymotrypsin. Effect on the properties of myosin.

1991 • 32 citations

Increases in phosphorylation of the myosin II heavy chain, but not regulatory light chains, correlate with insulin secretion in rat pancreatic islets and RINm5F cells.

1999 • 28 citations

Heparin inhibits Ca2+/calmodulin-dependent kinase II activation and c-fos induction in mesangial cells

1998 • 25 citations

Myosin reorganization in activated RBL cells correlates temporally with stimulated secretion

1994 • 20 citations

Calcium/Calmodulin-Dependent Protein Kinase II Involvement in Release of Gonadotropin-Releasing Hormone

1998 • 12 citations