Role of Cytotoxic T Cells in Chronic Alopecia Areata

Cytotoxic lymphocytes require granzyme B for the rapid induction of DNA fragmentation and apoptosis in allogeneic target cells

1994 • 844 citations

Purification of three cytotoxic lymphocyte granule serine proteases that induce apoptosis through distinct substrate and target cell interactions.

1992 • 447 citations

Analysis of apoptosis during hair follicle regression (catagen)

1997 • 353 citations

Autoimmune hair loss (alopecia areata) transferred by T lymphocytes to human scalp explants on SCID mice.

1998 • 253 citations

Role of Fas-mediated cell death in the regulation of immune responses

1996 • 243 citations

Production of interleukins in human immunodeficiency virus-1-replicating lymph nodes.

1990 • 237 citations

Balance of IL-1 receptor antagonist/IL-1 beta in rheumatoid synovium and its regulation by IL-4 and IL-10.

1995 • 195 citations

Induction of target cell DNA release by the cytotoxic T lymphocyte granule protease granzyme A.

1989 • 186 citations

Human cytotoxic lymphocyte granzyme B. Its purification from granules and the characterization of substrate and inhibitor specificity.

1991 • 185 citations

Expression of Fas Antigen on Keratinocytes In Vivo and Induction of Apoptosis in Cultured Keratinocytes

1994 • 175 citations

Bcl-2 prevents death of factor-deprived cells but fails to prevent apoptosis in targets of cell mediated killing

1992 • 165 citations

Immunohistochemical analysis of T-cell subsets in the peribulbar and intrabulbar infiltrates of alopecia areata

1984 • 137 citations

Expression of the bcl-2 Protooncogene in the Cycling Adult Mouse Hair Follicle

1994 • 122 citations

Apoptosis as the mechanism of the involution of hair follicles in catagen transformation

1981 • 100 citations

Expression of HLA-DR by Anagen Hair Follicles in Alopecia Areata

1985 • 99 citations

In vivodepletion of CD8⁺T cells restores hair growth in the DEBR model for alopecia areata

1996 • 88 citations

Immunohistochemical and Electron Microscopic Characterization of the Cellular Infiltrate in Alopecia (Areata, Totalis, and Universalis)

1984 • 77 citations

IL-1 alpha inhibits human hair follicle growth and hair fiber production in whole-organ cultures.

1993 • 76 citations

Intrabulbar and peribulbar accumulation of dendritic OKT 6-positive cells in alopecia areata

1984 • 57 citations

Activation of cytotoxic cells in hyperplastic lymph nodes from HIV-infected patients

1991 • 57 citations

IL-2 mRNA expression in Tac-positive malignant lymphomas.

1990 • 56 citations

Cell Degeneration in Alopecia Areata

1991 • 55 citations

Aberrant Intercellular Adhesion Molecule-1 (ICAM-1) Expression by Hair-Follicle Epithelial Cells and Endothelial Leukocyte Adhesion Molecule-1 (ELAM-1) by Vascular Cells Are Important Adhesion-Molecule Alterations in Alopecia Areata

1991 • 42 citations

Alopecia areata. Autoreactive T cells are variably enriched in scalp lesions relative to peripheral blood

1992 • 38 citations

Alopecia Areata

1992 • 31 citations

Growth factor mRNA levels in alopecia areata before and after treatment with the contact allergen diphenylcyclopropenone.

1996 • 30 citations

Immunologic Cytotoxicity in Alopecia Areata: Apoptosis of Dermal Papilla Cells in Alopecia Areata

1995 • 16 citations

Cytokine Patterns in Alopecia Areata Before and After Topical Immunotherapy

1995 • 7 citations