Insulin resistance and coronary artery disease

Role of Insulin Resistance in Human Disease

1988 • 12,099 citations

Glucose clamp technique: a method for quantifying insulin secretion and resistance.

1979 • 7,240 citations

Insulin Resistance: A Multifaceted Syndrome Responsible for NIDDM, Obesity, Hypertension, Dyslipidemia, and Atherosclerotic Cardiovascular Disease

1991 • 4,548 citations

Banting lecture 1988. Role of insulin resistance in human disease

1988 • 3,751 citations

Insulin Resistance in Essential Hypertension

1987 • 2,386 citations

Pathogenesis of NIDDM: A Balanced Overview

1992 • 2,111 citations

Hyperinsulinemia as an Independent Risk Factor for Ischemic Heart Disease

1996 • 1,727 citations

Quantitation of Muscle Glycogen Synthesis in Normal Subjects and Subjects with Non-Insulin-Dependent Diabetes by¹³C Nuclear Magnetic Resonance Spectroscopy

1990 • 1,226 citations

Hyperinsulinaemia: the key feature of a cardiovascular and metabolic syndrome

1991 • 930 citations

Measurement of Size and Turnover Rate of Body Glucose Pool by the Isotope Dilution Method

1956 • 827 citations

Coronary Heart Disease Incidence and Cardiovascular Mortality in Busselton with Reference to Glucose and Insulin Concentrations

1979 • 746 citations

Insulin resistance and hyperinsulinemia in individuals with small, dense low density lipoprotein particles.

1993 • 696 citations

The triglyceride issue: A view from Framingham

1986 • 675 citations

A METHOD FOR THE PREPARATION OF BLOOD FILTRATES FOR THE DETERMINATION OF SUGAR

1930 • 541 citations

Overall and coronary heart disease mortality rates in relation to major risk factors in 325,348 men screened for the MRFIT

1986 • 514 citations

Hyperinsulinaemia as a predictor of coronary heart disease mortality in a healthy population: the Paris Prospective Study, 15-year follow-up

1991 • 395 citations

Association of early-onset coronary heart disease in South Asian men with glucose intolerance and hyperinsulinemia.

1993 • 371 citations

Indirect calorimetry: methodological and interpretative problems

1990 • 370 citations

Effect of Antihypertensive Drugs on Insulin, Glucose, and Lipid Metabolism

1991 • 345 citations

Body fat distribution and hyperinsulinemia as risk factors for diabetes and cardiovascular disease.

1986 • 333 citations

Insulin Resistance, Hyperinsulinemia, Hypertriglyceridemia, and Hypertension: Parallels Between Human Disease and Rodent Models

1991 • 286 citations

Relationship between insulin resistance, insulin secretion, very low density lipoprotein kinetics, and plasma triglyceride levels in normotriglyceridemic man

1981 • 249 citations

THE EFFECT OF ALLOXAN DIABETES ON EXPERIMENTAL CHOLESTEROL ATHEROSCLEROSIS IN THE RABBIT

1949 • 247 citations

Asymptomatic atherosclerosis and insulin resistance.

1991 • 212 citations

Relation of Ocular and Systemic Factors to Survival in Diabetes

1989 • 199 citations

Effect of Intra-arterial Insulin on Tissue Cholesterol and Fatty Acids in Alloxan-Diabetic Dogs

1961 • 184 citations

Relationship between glucose tolerance, insulin secretion, and insulin action in non-obese individuals with varying degrees of glucose tolerance

1989 • 177 citations

Total body fat content and fat topography are associated differently with in vivo glucose metabolism in nonobese and obese nondiabetic women.

1992 • 148 citations

Excess Mortality Associated With Diuretic Therapy in Diabetes Mellitus

1991 • 144 citations

Asymptomatic atherosclerosis and insulin resistance.

1991 • 138 citations

Serum triglycerides are a risk factor for myocardial infarction but not for angina pectoris

1985 • 120 citations

High fasting plasma insulin is an indicator of coronary heart disease in non-insulin-dependent diabetic patients and nondiabetic subjects.

1991 • 112 citations

Insulin as a mitogenic factor: Role in the pathogenesis of cardiovascular disease

1991 • 104 citations

Total Body Fat Content and Fat Topography Are Associated Differently With In Vivo Glucose Metabolism in Nonobese and Obese Nondiabetic Women

1992 • 97 citations

Effect of Insulin in the Induction and Regression of Atherosclerosis in the Chick

1960 • 78 citations

Insulin in ischaemic heart disease: are associations explained by triglyceride concentrations? The Caerphilly prospective study.

1994 • 78 citations

Unexpected effects of treating hypertension in men with electrocardiographic abnormalities: a critical analysis.

1986 • 77 citations

Experimental Atherosclerosis-Like Lesions Induced by Hyperinsulinism in Wistar Rats

1989 • 69 citations

Dynamics of water-isotope distribution

1972 • 56 citations

Insulin Resistance and Abnormal Electrocardiograms in Patients With High Blood Pressure

1992 • 52 citations

High serum insulin concentrations in relation to other cardiovascular risk factors in macrovascular disease of type 2 diabetes.

1985 • 52 citations

United Kingdom Prospective Diabetes Study. III. Prevalence of hypertension and hypotensive therapy in patients with newly diagnosed diabetes. A multicenter study.

1985 • 46 citations

The effects of hyperinsulinemia on arterial wall and peripheral muscle metabolism in dogs

1985 • 44 citations

Relation of ocular and systemic factors to survival in diabetes

1989 • 43 citations

Hyperinsulinaemia is associated with development of electrocardiographic abnormalities in diabetics.

1984 • 43 citations

Experimental atherosclerosis-like lesions induced by hyperinsulinism in Wistar rats

1989 • 29 citations

Macrovascular complications in relation to hyperinsulinaemia in non-insulin-dependent diabetes mellitus.

1987 • 28 citations

Drugs and diabetes

1994 • 28 citations

Excess mortality associated with diuretic therapy in diabetes mellitus

1991 • 23 citations

Metabolic features of patients with and without coronary heart disease but with a superimposable cluster of cardiovascular risk factors

1993 • 7 citations