Body fat distribution and hyperinsulinemia as risk factors for diabetes and cardiovascular disease.

THE GLUCOSE FATTY-ACID CYCLE ITS ROLE IN INSULIN SENSITIVITY AND THE METABOLIC DISTURBANCES OF DIABETES MELLITUS

1963 • 5,061 citations

Obesity as an independent risk factor for cardiovascular disease: a 26-year follow-up of participants in the Framingham Heart Study.

1983 • 4,204 citations

Abdominal adipose tissue distribution, obesity, and risk of cardiovascular disease and death: 13 year follow up of participants in the study of men born in 1913.

1984 • 1,948 citations

Relation of Body Fat Distribution to Metabolic Complications of Obesity*

1982 • 1,919 citations

Distribution of adipose tissue and risk of cardiovascular disease and death: a 12 year follow up of participants in the population study of women in Gothenburg, Sweden.

1984 • 1,702 citations

Impact of obesity on metabolism in men and women. Importance of regional adipose tissue distribution.

1983 • 1,455 citations

The Degree of Masculine Differentiation of Obesities

1956 • 1,386 citations

The Influence of Body Fat Distribution on the Incidence of Diabetes Mellitus: 13.5 Years of Follow-up of the Participants in the Study of Men Born in 1913

1985 • 981 citations

Relationship of Glucose Tolerance and Plasma Insulin to the Incidence of Coronary Heart Disease: Results from Two Population Studies in Finland

1979 • 779 citations

Relationship of plasma insulin levels to the incidence of myocardial infarction and coronary heart disease mortality in a middle-aged population

1980 • 754 citations

Coronary Heart Disease Incidence and Cardiovascular Mortality in Busselton with Reference to Glucose and Insulin Concentrations

1979 • 746 citations

Epidemiology as a Guide to Clinical Decisions

1980 • 708 citations

Mechanisms of insulin resistance in human obesity: evidence for receptor and postreceptor defects.

1980 • 665 citations

Relationship of Androgenic Activity to Body Fat Topography, Fat Cell Morphology, and Metabolic Aberrations in Premenopausal Women*

1983 • 589 citations

The role of adipose cell size and adipose tissue insulin sensitivity in the carbohydrate intolerance of human obesity

1968 • 587 citations

Reappraisal of the role of insulin in hypertriglyceridemia

1974 • 480 citations

Hyperglycaemia as an inducer as well as a consequence of impaired islet cell function and insulin resistance: implications for the management of diabetes

1985 • 461 citations

Fat cell metabolism in different regions in women. Effect of menstrual cycle, pregnancy, and lactation.

1985 • 442 citations

Adipose tissue cellularity in human obesity

1976 • 434 citations

Obesity: new insight into the anthropometric classification of fat distribution shown by computed tomography.

1985 • 398 citations

Relationship of body fat topography to insulin sensitivity and metabolic profiles in premenopausal women

1984 • 391 citations

THE ASSOCIATION OF GIRTH MEASUREMENTS WITH DISEASE IN 32,856 WOMEN1

1984 • 387 citations

The growth of adipose tissue in children and adolescents. Cross-sectional and longitudinal studies of adipose cell number and size.

1979 • 374 citations

Nonketotic diabetes mellitus: Insulin deficiency or insulin resistance?

1976 • 361 citations

Decreased insulin binding to adipocytes and circulating monocytes from obese subjects.

1976 • 342 citations

Relationship of obesity to diabetes: Influence of obesity level and body fat distribution,

1983 • 332 citations

Risk factors for worsening to diabetes in subjects with impaired glucose tolerance

1984 • 322 citations

Mechanisms of insulin resistance in obesity and noninsulin-dependent (type II) diabetes

1981 • 305 citations

EVIDENCE FOR AN INCREASED RISK FOR HYPERTENSION WITH CENTRALLY LOCATED BODY FAT AND THE EFFECT OF RACE AND SEX ON THIS RISK

1984 • 305 citations

The Insulin Receptor: Its Role in Insulin Resistance of Obesity and Diabetes

1976 • 289 citations

The Influence of Obesity on Health

1974 • 283 citations

Coronary Heart Disease: Overweight and Obesity as Risk Factors

1972 • 242 citations

Diabetes and atherosclerosis ? The role of insulin

1979 • 222 citations

Carbohydrate storage in man: Speculations and some quantitative considerations

1978 • 212 citations

Role of insulin resistance in adipose tissue and liver in the pathogenesis of endogenous hypertriglyceridaemia in man

1976 • 204 citations

Relationship between skeletal muscle insulin resistance, insulin-mediated glucose disposal, and insulin binding. Effects of obesity and body fat topography.

1984 • 201 citations

The health consequences of moderate obesity.

1981 • 197 citations

Interrelationship Between Skinfold Thickness, Serum Lipids and Blood Sugar in Normal Men

1964 • 152 citations

Lipolysis and lipogenesis from glucose in human fat cells of different sizes

1970 • 146 citations

Effect of cell size on epinephrine- and ACTH-induced fatty acid release from isolated fat cells

1971 • 144 citations

Overweight, Obesity, Coronary Heart Disease and Mortality

2009 • 138 citations

Difference in Diabetic and Nondiabetic Fat Distribution Patterns by Skinfold Measurements

1969 • 130 citations

Quantification of body fat distribution in the abdomen using computed tomography

1984 • 130 citations

The Glucose Uptake of Human Adipose Tissue in Obesity

1971 • 118 citations

The relationship of abnormal circulating insulin levels to atherosclerosis

1977 • 116 citations

DOSE-RESPONSE RELATION BETWEEN PLASMA-INSULIN AND BLOOD-GLUCOSE LEVELS DURING ORAL GLUCOSE LOADS IN PREDIABETIC AND DIABETIC SUBJECTS

1973 • 115 citations

THE ROLE OF BEHAVIORAL VARIABLES AND FAT PATTERNING IN EXPLAINING ETHNIC DIFFERENCES IN SERUM LIPIDS AND LIPOPROTEINS1

1986 • 105 citations

The diabetes alert study: Growth, fatness, and fat patterning, adolescence through adulthood in Mexican Americans

1984 • 98 citations

Relative fat patterning: an individual characteristic.

1955 • 94 citations

The Influence of Obesity on Health

1974 • 93 citations

Factors influencing anatomic location of fat tissue in 52,953 women.

1985 • 86 citations

DIABETES MELLITUS IN TECUMSEH, MICHIGAN

1982 • 80 citations

FACTORS ASSOCIATED WITH THE DEVELOPMENT OF DIABETES IN THE MICRONESIAN POPULATION OF NAURU

1985 • 75 citations

Relationship of hypertriglyceridemia to atherosclerosis.

1981 • 73 citations

Female fat distribution--a photographic and cellularity study.

1978 • 71 citations

INSULIN EXCESS AS THE INITIAL LESION IN DIABETES

1972 • 70 citations

Preweaning Nutrition and Fat Development in Baboons

1983 • 63 citations

Abnormalities of Islet B-Cell Function, Insulin Action, and Fat Distribution in Women with Histories of Gestational Diabetes: Relationship to Obesity*

1985 • 62 citations

A Simplified Method Using Somatostatin to Assess In Vivo Insulin Resistance over a Range of Obesity

1979 • 59 citations

Diabetes Alert Study: Weight history and upper body obesity in diabetic and non-diabetic Mexican American adults

1984 • 57 citations

INTERPRETING MULTIPLE LOGISTIC REGRESSION COEFFICIENTS IN PROSPECTIVE OBSERVATIONAL STUDIES

1984 • 48 citations

Precursors of plasma triglyceride fatty acids in obesity

1973 • 43 citations

Blood glucose and atherosclerosis.

1981 • 43 citations

A new concept of impaired glucose tolerance. Relation to cardiovascular risk.

1985 • 39 citations

Epidemiology as a Guide to Clinical Decisions: The Association Between Triglyceride and Coronary Heart Disease

1980 • 37 citations

Effects of glucose and insulin on lipolysis rates in human fat cells of different sizes

1970 • 26 citations

Obesity: New insight into the anthropometric classification of fat distribution shown by computed tomography

1986 • 22 citations

Overweight, Obesity, Coronary Heart Disease, and Mortality

1980 • 21 citations

Reappraisal of the role of insulin in hypertriglyceridemia

1974 • 16 citations

A simplified method using somatostatin to assess in vivo insulin resistance over a range of obesity

1979 • 15 citations