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Effect of ACTH suppression on adrenal 3-hydroxy-3-methylglutaryl coenzyme A reductase mRNA in 4-aminopyrazolopyrimidine-treated rats

Data up to Jan 2025

Published1990
Citations11
References32

Total Citations Per Year

Abstract

References (32)

Cytoplasmic dot hybridization. Simple analysis of relative mRNA levels in multiple small cell or tissue samples.

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Multivalent control of 3-hydroxy-3-methylglutaryl coenzyme A reductase. Mevalonate-derived product inhibits translation of mRNA and accelerates degradation of enzyme.

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Lipoprotein-mediated regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity and cholesteryl ester metabolism in the adrenal gland of the rat.

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1983 • 200 citations

Operator constitutive mutation of 3-hydroxy-3-methylglutaryl coenzyme A reductase promoter abolishes protein binding to sterol regulatory element.

1988 • 194 citations

Regulation of low density lipoprotein receptors by adrenocorticotropin in the adrenal gland of mice and rats in vivo.

1980 • 116 citations

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1989 • 107 citations

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1981 • 81 citations

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1988 • 74 citations

Phosphorylation of Native 97-kDa 3-Hydroxy-3-methylglutaryl-coenzyme A Reductase from Rat Liver

1989 • 70 citations

De novo synthesis of corticosteroids in hamster adrenal glands

1980 • 48 citations

Effect of 4-Aminopyrazolopyrimidine and Aminoglutethimide on Cholesteryl Metabolism and Steroidogenesis in the Rat Adrenal*

1978 • 40 citations

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1986 • 39 citations

8-Bromoadenosine cyclic 3',5'-phosphate rapidly increases 3-hydroxy-3-methylglutaryl coenzyme A reductase mRNA in human granulosa cells: role of cellular sterol balance in controlling the response to tropic stimulation

1988 • 37 citations

Regulation of 3-hydroxy-3-methylglutaryl coenzyme a reductase activity in human fibroblasts by reversible phosphorylation: Modulation of enzymatic activity by low density lipoprotein, sterols, and mevalonolactone

1986 • 31 citations

ACTH induction of 3-hydroxy-3-methylglutaryl coenzyme A reductase, cholesterol biosynthesis, and steroidogenesis in primary cultures of bovine adrenocortical cells.

1986 • 29 citations

Effects of ACTH and aminoglutethimide administration on the morphological and functional responses of rat adrenal zona fasciculata to a prolonged treatment with 4-aminopyrazolo-pyrimidine.

1987 • 18 citations

Effects of mevinolin, an inhibitor of cholesterol synthesis, on the morphological and functional responses of rat adrenal zona fasciculata to a prolonged treatment with 4‐aminopyrazolo‐pyrimidine

1988 • 18 citations

The effect of ACTH on HMG-CoA reductase activity in hamster adrenals

1981 • 18 citations

Effect of ACTH on cholesterol and steroid synthesis in adrenocortical tissues

1987 • 17 citations

Changes in characteristics of rat adrenal glomerulosa cells under acute and chronic treatment with ACTH

1983 • 17 citations

Effects of excess dietary cholesterol on adrenal cholesterol accumulation and steroidogenesis

1984 • 14 citations

3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase in OuterVersusInner Cortices of the Guinea Pig Adrenal: Effects of Adrenocorticotropin and Dexamethasone*

1988 • 14 citations

Long term effects of the hypocholesterolaemic drug 4-aminopyrazolo-pyrimidine on the zona fasciculata of the rat adrenal cortex.

1986 • 13 citations

The Enhancing Effect of Adrenocorticotropin on Adrenal 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Messenger Ribonucleic Acid Level Is Inhibited by Aminoglutethimide but not by Cycloheximide*

1989 • 10 citations

Characterization of 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase in Human Adrenal Cortex*

1985 • 9 citations

On the control of HMG-CoA reductase, a key regulatory enzyme of adrenal cholesterol synthesis

1986 • 6 citations

Adrenocorticotropin and the Time of Day both Influence the Amount and Activity of 3-Hydroxy-3-Methylglutaryl Coenzyme-A Reductase in the Hamster Adrenal*

1987 • 5 citations

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Effect of ACTH suppression on adrenal 3-hydroxy-3-methylglutaryl coenzyme A reductase… (1990) – Molecular and Cellular Endocrinology | Metascience Observatory Explorer