Development of angiogenesis inhibitors for clinical applications

Inhibition of endothelial cell movement by pericytes and smooth muscle cells: activation of a latent transforming growth factor-beta 1-like molecule by plasmin during co-culture.

1989 • 914 citations

Tissue Inhibitor of Metalloproteinase (TIMP-2)

1989 • 899 citations

Two different laminin domains mediate the differentiation of human endothelial cells into capillary-like structures in vitro

1989 • 746 citations

Inhibition of Angiogenesis by Recombinant Human Platelet Factor-4 and Related Peptides

1990 • 710 citations

Angiogenesis Inhibition and Tumor Regression Caused by Heparin or a Heparin Fragment in the Presence of Cortisone

1983 • 622 citations

Protamine is an inhibitor of angiogenesis

1982 • 582 citations

A New Class of Steroids Inhibits Angiogenesis in the Presence of Heparin or a Heparin Fragment

1985 • 492 citations

Inhibition of angiogenesis by interferons: effects on tumor- and lymphocyte-induced vascular responses.

1987 • 491 citations

Identification of an Inhibitor of Neovascularization from Cartilage

1990 • 481 citations

Regulation of the activity of a new inhibitor of angiogenesis by a cancer suppressor gene

1989 • 475 citations

Treatment of Pulmonary Hemangiomatosis with Recombinant Interferon Alfa-2a

1989 • 444 citations

Inhibition of Endothelial Regeneration by Type-Beta Transforming Growth Factor from Platelets

1986 • 439 citations

Basement Membrane Collagen: Degradation by Migrating Endothelial Cells

1983 • 345 citations

Control of Angiogenesis with Synthetic Heparin Substitutes

1989 • 292 citations

Inhibition of angiogenesis through modulation of collagen metabolism.

1988 • 240 citations

Transforming growth factor-beta (TGFβ) is chemotactic for human monocytes and induces their expression of angiogenic activity

1988 • 233 citations

Human skin fibroblast collagenase inhibitor. Comparative studies in human connective tissues, serum, and amniotic fluid.

1983 • 231 citations

Analysis of the histologic variation of synovitis in rheumatoid arthritis

1988 • 217 citations

Shark Cartilage Contains Inhibitors of Tumor Angiogenesis

1983 • 204 citations

Inhibition of in vitro vascular endothelial cell proliferation and in vivo neovascularization by low‐dose methotrexate

1989 • 202 citations

Growth Inhibition of Murine Melanoma and Human Colon Carcinoma by Recombinant Human Platelet Factor 4

1990 • 190 citations

Methotrexate therapy in rheumatoid arthritis: 15 years experience

1983 • 176 citations

A highly potent antiangiogenic activity of retinoids

1989 • 143 citations

Inhibition of human endothelial cell proliferation in vitro and neovascularization in vivo by D-penicillamine.

1989 • 123 citations

Adrenal Suppression After Corticosteroid Injection of Periocular Hemangiomas

1989 • 83 citations

Systemic treatment of psoriasis with an oral retinoic acid derivative (Ro 10-9359)

1980 • 82 citations

Neovascularisation and its role in the osteoarthritic process.

1988 • 80 citations

Monoclonal antibodies directed against basic fibroblast growth factor which inhibit its biological activity in vitro and in vivo

1989 • 72 citations

Biological and chemical characterization of basic FGF-saporin mitotoxin

1989 • 64 citations

Angiogenesis and the skin

1987 • 44 citations

Interferon Therapy for Kaposi Sarcoma Associated with the Acquired Immunodeficiency Syndrome (AIDS)

1989 • 43 citations

Inhibition of angiogenesis by the antineoplastic agents mitoxantrone and bisantrene

1986 • 41 citations

Partial purification of a 5.7K glycoprotein from bovine vitreous which inhibits both angiogenesis and collagenase activity

1985 • 40 citations

The Inhibition of Corneal Vascularization with Aortic Extracts in Rabbits

1979 • 30 citations

Angiogenic activity of the atherosclerotic carotid artery plaque

1989 • 30 citations

Inhibition of tumour‐induced angiogenesis by systemically administered protamine sulphate

1984 • 25 citations

Complete resolution of Kaposi's sarcoma with systemic etretinate therapy in a patient with mycosis fungoides

1989 • 17 citations

Smooth muscle cells produce an inhibitor of endothelial cell growth.

1985 • 12 citations

METHOTREXATE FOR PSORIASIS

1963 • 4 citations

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