Antithrombin III (ATILL) replacement therapy in patients with sepsis and/or postsurgical complications: a controlled double-blind, randomized, multicenter study

Definitions for Sepsis and Organ Failure and Guidelines for the Use of Innovative Therapies in Sepsis

1992 • 12,726 citations

APACHE II

1985 • 12,347 citations

American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference

1992 • 4,689 citations

Multiple-Organ Failure

1985 • 1,314 citations

A simplified acute physiology score for ICU patients

1984 • 1,244 citations

American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference: definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis.

1992 • 942 citations

Multiple Organ Failure

1999 • 820 citations

Septic Shock, Multiple Organ Failure, and Disseminated Intravascular Coagulation

1992 • 708 citations

Double-blind, Placebo-controlled Trial of Antithrombin III Concentrates in Septic Shock With Disseminated Intravascular Coagulation

1993 • 379 citations

Antithrombin III in patients with severe sepsis

1998 • 335 citations

The Italian SEPSIS study: Preliminary results on the incidence and evolution of SIRS, sepsis, severe sepsis and septic shock

1995 • 257 citations

Substitution of antithrombin III in shock and DIC: A randomized study

1985 • 207 citations

Factor VIIa and antithrombin III activity during severe sepsis and septic shock in neutropenic patients

1996 • 196 citations

Coagulation, fibrinolysis, and kallikrein systems in sepsis

1989 • 159 citations

Protein C, protein S and C4b-binding protein in severe infection and septic shock.

1991 • 145 citations

Acquired antithrombin III deficiency: Laboratory diagnosis, incidence, clinical implications, and treatment with antithrombin III concentrate

1989 • 121 citations

The Suprapharmacologic Dosing of Antithrombin Concentrate for Staphylococcus Aureus-Induced Disseminated Intravascular Coagulation in Guinea Pigs: Substantial Reduction in Mortality and Morbidity

1997 • 99 citations

Substitution therapy with an antithrombin III concentrate in shock and DIC

1982 • 90 citations

Therapeutic Use of Antithrombin III in Shock and Disseminated Intravascular Coagulation

1989 • 72 citations

Antithrombin III Concentrates-Are they Clinically Useful?

1995 • 71 citations

Reduction of Mortality with Antithrombin III in Septicemic Rats: A Study of Klebsiella pneumoniae Induced Sepsis

1993 • 70 citations

Clinical Evaluation of Antithrombin III Concentrate (BI 6.013) for Disseminated Intravascular Coagulation in Obstetrics

1987 • 59 citations

Plasma Prekallikrein, Factor XII, Antithrombin III, C1−-Inhibitor and α2-Macroglobulin in Critically III Patients with Suspected Disseminated Intravascular Coagulation (DIC)

1984 • 55 citations

Influence of high-dose antithrombin concentrate therapy on the release of cellular proteinases, cytokines, and soluble adhesion molecules in acute inflammation.

1995 • 51 citations

Extrinsic Pathway Inhibitor in Postoperative/Posttraumatic Septicemia: Increased Levels in Fatal Cases

1989 • 45 citations

Antithrombin, Prekallikrein, and Fibronectin Levels in Surgical Patients

1986 • 42 citations