Vaccination strategies for lymphomas

Tolerance, Danger, and the Extended Family

1994 • 4,654 citations

Direct Gene Transfer into Mouse Muscle in Vivo

1990 • 3,985 citations

Cancer Statistics, 2003

2003 • 3,302 citations

Heterologous Protection Against Influenza by Injection of DNA Encoding a Viral Protein

1993 • 2,330 citations

Innate immunity: impact on the adaptive immune response

1997 • 1,542 citations

Chemokines and Cell Migration in Secondary Lymphoid Organs

1999 • 1,046 citations

An innate sense of danger

1998 • 752 citations

Complete molecular remissions induced by patient-specific vaccination plus granulocyte–monocyte colony-stimulating factor against lymphoma

1999 • 604 citations

Idiotype-pulsed dendritic cell vaccination for B-cell lymphoma: clinical and immune responses in 35 patients

2002 • 553 citations

Induction of Immune Responses in Patients with B-Cell Lymphoma against the Surface-Immunoglobulin Idiotype Expressed by Their Tumors

1992 • 551 citations

Tumor-Specific Idiotype Vaccines in the Treatment of Patients With B-Cell Lymphoma — Long-Term Results of a Clinical Trial

1997 • 464 citations

The mannose receptor functions as a high capacity and broad specificity antigen receptor in human dendritic cells

1997 • 397 citations

The Makings of a Tumor Rejection Antigen

1999 • 389 citations

Non-Hodgkin's lymphoma time trends: United States and international data.

1992 • 363 citations

An Innate Sense of Danger

2002 • 355 citations

The role of CpG motifs in innate immunity

2000 • 349 citations

CD40-ligand (CD154) gene therapy for chronic lymphocytic leukemia

2000 • 345 citations

Myeloma Proteins as Tumor-Specific Transplantation Antigens

1972 • 325 citations

Idiotype/granulocyte-macrophage colony-stimulating factor fusion protein as a vaccine for B-cell lymphoma

1993 • 314 citations

DNA vaccines with single-chain Fv fused to fragment C of tetanus toxin induce protective immunity against lymphoma and myeloma

1998 • 303 citations

Mediators of Innate Immunity That Target Immature, But Not Mature, Dendritic Cells Induce Antitumor Immunity When Genetically Fused with Nonimmunogenic Tumor Antigens

2001 • 280 citations

Genetic fusion of chemokines to a self tumor antigen induces protective, T-cell dependent antitumor immunity

1999 • 278 citations

Transfer of myeloma idiotype-specific immunity from an actively immunised marrow donor

1995 • 269 citations

Emergence of Idiotype Variants during Treatment of B-Cell Lymphoma with Anti-Idiotype Antibodies

1985 • 257 citations

DNA immunization induces protective immunity against B–cell lymphoma

1996 • 252 citations

Vaccination with syngeneic, lymphoma-derived immunoglobulin idiotype combined with granulocyte/macrophage colony-stimulating factor primes mice for a protective T-cell response.

1996 • 232 citations

Use of family specific leader region primers for PCR amplification of the human heavy chain variable region gene repertoire

1992 • 190 citations

Immunization with granulocyte-macrophage colony-stimulating factor-transduced, but not B7-1-transduced, lymphoma cells primes idiotype-specific T cells and generates potent systemic antitumor immunity.

1996 • 185 citations

Immunogenicity of a plasmid DNA vaccine encoding chimeric idiotype in patients with B-cell lymphoma.

2002 • 180 citations

Idiotype vaccination against murine B cell lymphoma. Inhibition of tumor immunity by free idiotype protein.

1987 • 168 citations

Idiotypic vaccination against human B-cell lymphoma. Rescue of variable region gene sequences from biopsy material for assembly as single-chain Fv personal vaccines

1994 • 155 citations

Idiotype-cytokine fusion proteins as cancer vaccines. Relative efficacy of IL-2, IL-4, and granulocyte-macrophage colony-stimulating factor.

1994 • 135 citations

Idiotypic DNA Vaccines Against B‐cell Lymphoma

1995 • 134 citations

4-1BBL Cooperates with B7-1 and B7-2 in Converting a B Cell Lymphoma Cell Line into a Long-Lasting Antitumor Vaccine

1999 • 130 citations

Immunization against murine multiple myeloma with fusions of dendritic and plasmacytoma cells is potentiated by interleukin 12

2002 • 123 citations

Sperm protein 17 (Sp17) is a suitable target for immunotherapy of multiple myeloma

2002 • 103 citations

B7-CD28 costimulation unveils the hierarchy of tumor epitopes recognized by major histocompatibility complex class I-restricted CD8+ cytolytic T lymphocytes.

1996 • 100 citations

DNA Fusion Vaccine Designed to Induce Cytotoxic T Cell Responses Against Defined Peptide Motifs: Implications for Cancer Vaccines

2001 • 99 citations

ALK as a novel lymphoma-associated tumor antigen: identification of 2 HLA-A2.1–restricted CD8+ T-cell epitopes

2002 • 96 citations

DNA vaccines against lymphoma: promotion of anti-idiotypic antibody responses induced by single chain Fv genes by fusion to tetanus toxin fragment C.

1997 • 95 citations

Idiotypic determinants on the surface immunoglobulin of neoplastic lymphocytes: a therapeutic target.

1977 • 90 citations

From cancer genomics to cancer immunotherapy: toward second-generation tumor antigens

2001 • 88 citations

Plant viral genes in DNA idiotypic vaccines activate linked CD4+ T-cell mediated immunity against B-cell malignancies

2001 • 83 citations

Stimulation of cytotoxic T cells against idiotype immunoglobulin of malignant lymphoma with protein-pulsed or idiotype-transduced dendritic cells

2000 • 76 citations

PROTECTIVE AND CELLULAR IMMUNE RESPONSES TO IDIOTYPIC DETERMINANTS ON CELLS FROM A SPONTANEOUS LYMPHOMA OF NZB/NZW F1 MICE

1974 • 75 citations

A Genetic Approach to Idiotypic Vaccination

1993 • 69 citations

Increased potency of Fc-receptor-targeted antigens

1997 • 69 citations

Idiotype-encoding recombinant adenoviruses provide protective immunity against murine B-cell lymphomas

2001 • 68 citations

Idiotype Vaccines for Non-Hodgkin's Lymphoma Induce Polyclonal Immune Responses That Cover Mutated Tumor Idiotypes: Comparison of Different Vaccine Formulations

1997 • 61 citations

Liposomal formulation of a self lymphoma antigen induces potent protective antitumor immunity.

1998 • 51 citations

Antitumor Immunity After Vaccination With B Lymphoma Cells Overexpressing a Triad of Costimulatory Molecules

2003 • 48 citations

In vivo antitumor effect of CD40L-transduced tumor cells as a vaccine for B-cell lymphoma.

2002 • 45 citations

Cutting Edge: Liposomal Formulation of a Self Lymphoma Antigen Induces Potent Protective Antitumor Immunity

1998 • 45 citations

Tumor Immunity Induced by Preimmunization With BALB/c Mouse Myeloma Protein2

1976 • 45 citations

Immunization with the Light Chain and the V_L Domain of the Isologous Myeloma Protein 315 Inhibits Growth of Mouse Plasmacytoma MOPC315

1980 • 40 citations

Idiotype vaccination following ABMT can stimulate specific anti-idiotype immune responses in patients with B-cell lymphoma

2001 • 37 citations

DNA fusion vaccines against B-cell tumors

2001 • 30 citations

Inducing long-term survival with lasting anti-tumor immunity in treating B cell lymphoma by a combined dendritic cell-based and hydrodynamic plasmid-encoding IL-12 gene therapy

2003 • 30 citations

Tumor vaccination strategies combined with autologous peripheral stem cell transplantation

1998 • 22 citations