Acyclovir — A review of the preclinical and early clinical data of a new antiherpes drug

9-(2-Hydroxyethoxymethyl)guanine activity against viruses of the herpes group

1978 • 1,136 citations

Comparative Efficacy of Antiherpes Drugs against Different Strains of Herpes Simplex Virus

1980 • 603 citations

Thymidine kinase from herpes simplex virus phosphorylates the new antiviral compound, 9-(2-hydroxyethoxymethyl)guanine.

1978 • 560 citations

Inhibition of herpes simplex virus-induced DNA polymerase activity and viral DNA replication by 9-(2-hydroxyethoxymethyl)guanine and its triphosphate

1979 • 348 citations

Growth Inhibition by Acycloguanosine of Herpesviruses Isolated from Human Infections

1979 • 272 citations

Pathogenicity in mice of strains of herpes simplex virus which are resistant to acyclovir in vitro and in vivo

1980 • 245 citations

In vitro susceptibility of varicella-zoster virus to acyclovir

1980 • 222 citations

Effect of acyclovir [9-(2-hydroxyethoxymethyl)guanine] on Epstein-Barr virus DNA replication

1980 • 219 citations

Altered substrate specificity of herpes simplex virus thymidine kinase confers acyclovir-resistance

1981 • 208 citations

Effect of Acycloguanosine Treatment on Acute and Latent Herpes Simplex Infections in Mice

1979 • 177 citations

Isolation and Characterization of Acyclovir-resistant Mutants of Herpes Simplex Virus

1980 • 152 citations

Acyclovir kinetics after intravenous infusion

1979 • 121 citations

Latent Herpes Simplex Virus Infections in Sensory Ganglia of Hairless Mice Prevented by Acycloguanosine

1979 • 110 citations

Randomised double-blind trial of acyclovir and idoxuridine in dendritic corneal ulceration.

1980 • 100 citations

Novel substrate of adenosine deaminase

1971 • 82 citations

A comparison of acyclovir and idoxuridine as treatment for ulcerative herpetic keratitis.

1980 • 78 citations

Therapy of Experimental Herpes Simplex Encephalitis with Aciclovir in Mice

1979 • 68 citations

Acyclic Antimetabolite Therapy of Experimental Herpes Simplex Keratitis

1978 • 67 citations

Effect of 9-(2-Hydroxyethoxymethyl)guanine on Herpesvirus-Induced Keratitis and Iritis in Rabbits

1978 • 66 citations

Acyclovir in Oral and Ganglionic Herpes Simplex Virus Infections

1979 • 66 citations

Treatment of experimental herpes simplex keratitis with acycloguanosine.

1979 • 63 citations

Successful treatment of experimental B virus (Herpesvirus simiae) infection with acyclovir.

1980 • 55 citations

Herpetic Ganglionic Latency

1979 • 44 citations

Effect of Acyclovir on Recurrence of Herpes Simplex Skin Lesions in Mice

1980 • 41 citations

Efficacy of acycloguanosine against herpetic ulcers in rabbit cornea.

1979 • 36 citations

Comparative in vitro imunotoxicology of acyclovir and other antiviral agents

1980 • 32 citations

Aciclovir and Corneal Wound Healing

1979 • 31 citations

Experimental skin infection with an Acyclovir resistant herpes simplex virus mutant: Response to antiviral treatment and protection against reinfection

1980 • 29 citations

Aciclovir and Trifluorothymidine in herpetic keratitis preliminary report of a multicentered trial

1981 • 25 citations

Aciclovir Treatment in Experimental Herpetic Keratitis in Rabbits

1980 • 14 citations

Toxicity and Tolerance of 9-(2-Hydroxyethoxymethyl)Guanine

1980 • 11 citations