Experimental skin infection with an Acyclovir resistant herpes simplex virus mutant: Response to antiviral treatment and protection against reinfection

Selectivity of action of an antiherpetic agent, 9-(2-hydroxyethoxymethyl)guanine

1977 • 1,565 citations

Thymidine kinase from herpes simplex virus phosphorylates the new antiviral compound, 9-(2-hydroxyethoxymethyl)guanine.

1978 • 560 citations

The pathogenicity of thymidine kinase-deficient mutants of herpes simplex virus in mice

1978 • 337 citations

Trigeminal Ganglion Infection by Thymidine Kinase-Negative Mutants of Herpes Simplex Virus

1979 • 175 citations

Herpes simplex virus thymidine kinase expression in infection of the trigeminal ganglion

1979 • 159 citations

Acute and Latent Infection of Sensory Ganglia with Herpes Simplex Virus: Immune Control and Virus Reactivation

1979 • 143 citations

Latent Herpes Simplex Virus Infections in Sensory Ganglia of Hairless Mice Prevented by Acycloguanosine

1979 • 110 citations

Antiviral Activity of Arabinosylthymine in Herpesviral Replication: Mechanism of Action In Vivo and In Vitro

1977 • 101 citations

Latent Infection of Sensory Ganglia with Herpes Simplex Virus: Efficacy of Immunization

1975 • 98 citations

Host defenses in herpes simplex infections of the nervous system: effect of antibody on disease and viral spread

1979 • 94 citations

Temperature-sensitive mutants of herpes simplex virus differ in the capacity to establish latent infections in mice

1977 • 59 citations

Protection from oral herpes simplex virus infection by a nucleic acid-free virus vaccine

1977 • 54 citations

Phosphonoacetic Acid-Resistant Herpes Simplex Virus Infection in Hairless Mice

1975 • 51 citations

Route of infection, systemic host resistance, and integrity of ganglionic axons influence acute and latent herpes simplex virus infection of the superior cervical ganglion

1979 • 50 citations

Detection by complementation of defective or uninducible (herpes simplex type 1) virus genomes latent in human ganglia.

1979 • 49 citations

Viral-specific thymidine kinase in sensory ganglia of mice infected with herpes simplex virus

1977 • 42 citations

Orofacial Herpes Simplex Virus Infection in Hairless Mice: Latent Virus in Trigeminal Ganglia After Topical Antiviral Treatment

1978 • 37 citations

Acute infection of differentiated neuroblastoma cells by latency-positive and latency-negative herpes simplex virus is mutants

1979 • 34 citations

Phosphorylation of 5-iodo-5'-amino-2',5',dideoxyuridine by herpes simplex virus type 1 encoded thymidine kinase.

1979 • 32 citations

Isolation of herpes simplex virus clones and drug resistant mutants in microcultures

1975 • 31 citations

Immune response and latent infection after topical treatment of herpes simplex virus infection in hairless mice

1977 • 29 citations

In vivo behaviour of a temperature-sensitive (ts) mutant of herpesvirus hominis type 2

1973 • 23 citations

Latent herpes simplex virus in ganglia of mice after primary infection and reinoculation at a distant site

1978 • 22 citations