The discovery of immunologic tolerance

Tolerance, Danger, and the Extended Family

1994 • 4,654 citations

‘Actively Acquired Tolerance’ of Foreign Cells

1953 • 3,103 citations

T cell tolerance by clonal elimination in the thymus

1987 • 2,248 citations

Immunogenetic Consequences of Vascular Anastomoses Between Bovine Twins

1945 • 1,352 citations

Cell migration, chimerism, and graft acceptance

1992 • 1,075 citations

Self-tolerance eliminates T cells specific for Mls-modified products of the major histocompatibility complex

1988 • 1,036 citations

T-cell receptor Vβ use predicts reactivity and tolerance to Mlsa- encoded antigens

1988 • 901 citations

Neonatal Tolerance Revisited: Turning on Newborn T Cells with Dendritic Cells

1996 • 770 citations

Quantitative Studies on Tissue Transplantation Immunity. III. Actively Acquired Tolerance

1956 • 693 citations

Induction of T _H 1 and T _H 2 Immunity in Neonatal Mice

1996 • 671 citations

The production of antibodies

1949 • 526 citations

Induction of Protective CTL Responses in Newborn Mice by a Murine Retrovirus

1996 • 449 citations

Systemic chimerism in human female recipients of male livers

1992 • 378 citations

CHIMERISM AND DONOR-SPECIFIC NONREACTIVITY 27 TO 29 YEARS AFTER KIDNEY ALLOTRANSPLANTATION

1993 • 346 citations

The use of skin grafting to distinguish between monozygotic and dizygotic twins in cattle

1951 • 344 citations

The Theory of the Free-Martin

1916 • 337 citations

The effect of thymus environment on T cell development and tolerance

1988 • 330 citations

Biological Problems of Grafting

1960 • 231 citations

AUTO-IMMUNITY IN HASHIMOTO'S DISEASE AND ITS IMPLICATIONS*

1957 • 204 citations

IMMUNOLOGIC UNRESPONSIVENESS INDUCED BY PROTEIN ANTIGENS

1955 • 201 citations

Tolerance to homografts, twin diagnosis, and the freemartin condition in cattle

1952 • 186 citations

Mixed allogeneic chimeras prepared by a non-myeloablative regimen: requirement for chimerism to maintain tolerance.

1992 • 140 citations

THE EPIDEMIOLOGY OF LYMPHOCYTIC CHORIOMENINGITIS IN WHITE MICE

1936 • 135 citations

A History of Transplantation Immunology

2011 • 124 citations

Inhibition of Antibody Formation in Mature Rabbits by Contact with the Antigen at an Early Age

1954 • 116 citations

DONOR-RECIPIENT MICROCHIMERISM IS NOT REQUIRED FOR TOLERANCE INDUCTION FOLLOWING RECIPIENT PRETREATMENT WITH DONOR-SPECIFIC TRANSFUSION AND ANTI-CD4 ANTIBODY

1995 • 86 citations

The Wisdom of Hindsight

1994 • 84 citations

Clonal deletion of self-reactive T cells in irradiation bone marrow chimeras and neonatally tolerant mice. Evidence for intercellular transfer of Mlsa.

1989 • 76 citations

The Importance of Chimerism in Maintaining Tolerance of Skin Allografts in Mice

1973 • 73 citations

FACTORS OF RESISTANCE TO HETEROPLASTIC TISSUE-GRAFTING

1914 • 72 citations

Is immunological tolerance (non-responsiveness) a consequence of interleukin 2 deficit during the recognition of antigen?

1984 • 67 citations

QUINTUPLET CALVES AND ERYTHROCYTE MOSAICISM*

1946 • 62 citations

ACTIVELY ACQUIRED TOLERANCE TO HETEROLOGOUS ANTIGENS

1956 • 29 citations

Prolongation of Skin Allograft Survival with Spleen Extracts and Antilymphocytic Serum

1970 • 27 citations

The Abolition of Tolerance of Skin Homografts in Rats with Isoantiserum

1970 • 25 citations