Elevated Levels of Tumor Necrosis Factor-α in the Nephrotic Syndrome in Humans

PATHOGENESIS OF LIPOID NEPHROSIS: A DISORDER OF T-CELL FUNCTION

1974 • 1,152 citations

Purification of cachectin, a lipoprotein lipase-suppressing hormone secreted by endotoxin-induced RAW 264.7 cells.

1985 • 833 citations

Tumor necrosis factor/cachectin interacts with endothelial cell receptors to induce release of interleukin 1.

1986 • 709 citations

Associated Focal and Segmental Glomerulosclerosis in the Acquired Immunodeficiency Syndrome

1984 • 602 citations

Interferon‐γ and tumor necrosis factor induce the L‐arginine‐dependent cytotoxic effector mechanism in murine macrophages^*

1988 • 511 citations

In vivo treatment of (NZB X NZW)F1 lupus-like nephritis with monoclonal antibody to gamma interferon.

1987 • 396 citations

Tumor necrosis factor/cachectin stimulates peritoneal macrophages, polymorphonuclear neutrophils, and vascular endothelial cells to synthesize and release platelet-activating factor.

1987 • 364 citations

Increased tumor necrosis factor and IL-1 beta gene expression in the kidneys of mice with lupus nephritis.

1988 • 321 citations

RECURRENCE OF IDIOPATHIC NEPHROTIC SYNDROME AFTER RENAL TRANSPLANTATION

1972 • 296 citations

Interleukin 1-α and tumor necrosis factor-α induce oxygen radical production in mesangial cells

1990 • 286 citations

Uromodulin (Tamm-Horsfall Glycoprotein): a Renal Ligand for Lymphokines

1987 • 278 citations

Tamm-Horsfall protein—uromodulin (1950–1990)

1990 • 262 citations

Tumor necrosis factor and IL-1 in New Zealand Black/White mice. Enhanced gene expression and acceleration of renal injury.

1989 • 255 citations

Tumor necrosis factor induces glomerular damage in the rabbit.

1989 • 244 citations

The Acute Metabolic Effects of Tumor Necrosis Factor Administration in Humans

1987 • 236 citations

Production of tumor necrosis factor by rat mesangial cells in response to bacterial lipopolysaccharide

1989 • 220 citations

Cyclosporine A induced remission of relapsing nephrotic syndrome in children

1988 • 168 citations

Tumor necrosis factor and interleukin 1 alpha increase vascular endothelial permeability

1989 • 168 citations

Modulation of antibody-mediated glomerular injury in vivo by bacterial lipopolysaccharide, tumor necrosis factor, and IL-1.

1989 • 167 citations

Glomerular lesions in lymphomas and leukemias

1986 • 164 citations

Increased urinary protein excretion in the rat produced by serum from a patient with recurrent focal glomerular sclerosis after renal transplantation.

1984 • 159 citations

Tumor necrosis factor alpha activates soluble guanylate cyclase in bovine glomerular mesangial cells via an L-arginine-dependent mechanism.

1990 • 131 citations

Effects of tumor necrosis factor on the interferon‐γ‐induced major histocompatibility complex class II antigen expression by human endothelial cells

1988 • 113 citations

Endothelial cell activation induced by tumor necrosis factor and lymphotoxin.

1989 • 106 citations

DIFFERENTIAL IN SITU EXPRESSION OF CYTOKINES IN RENAL ALLOGRAFT REJECTION

1991 • 102 citations

INHIBITION OF LYMPHOCYTE BLASTOGENESIS BY PLASMA OF PATIENTS WITH MINIMAL-CHANGE NEPHROTIC SYNDROME

1976 • 100 citations

Mesangial cell accessory functions: Mediation by intercellular adhesion molecule-1

1990 • 97 citations

Recurrence of focal segmental sclerosis in children following renal transplantation.

1986 • 88 citations

Effect of interferon-γ and tumor necrosis factor on the expression of class I and class II major histocompatibility molecules by cultured human umbilical vein endothelial cells

1988 • 78 citations

Pathogenesis of Membranous Nephropathy

1988 • 77 citations

Changes in the glomerular capillary wall induced by lymphocyte products and serum of nephrotic patients.

1983 • 73 citations

The pathogenesis of minimal change nephropathy.

1977 • 66 citations

Identification and initial characterization of concanavalin A- and interferon-induced human suppressor factors: evidence for a human equivalent of murine soluble immune response suppressor (SIRS).

1984 • 62 citations

Treatment of Idiopathic Membranous Nephropathy Unresponsive to Methylprednisolone and Chlorambucil with Cyclosporin

1987 • 59 citations

Immune Mechanisms in Idiopathic Membranous Nephropathy: The Role of the Interstitial Infiltrates

1989 • 58 citations

Mononuclear cells in glomeruli and cytokines in urine reflect the severity of experimental proliferative immune complex glomerulonephritis

1990 • 49 citations

Differentiation between vascular permeability factor and IL-2 in lymphocyte supernatants from patients with minimal-change nephrotic syndrome

1991 • 43 citations

Cell-Mediated Immunity in Glomerular Disease

1991 • 41 citations

Glomerular basement membrane-containing immune complexes stimulate tumor necrosis factor and interleukin-1 production by human monocytes.

1989 • 38 citations

The Biology of Mesangial Cells in Glomerulonephritis

1990 • 26 citations

Decreased Production and Responsiveness of Interleukin 2 in Lymphocytes of Patients with Nephrotic Syndrome

1990 • 23 citations

Multiple serum inhibitors of lectin-induced lymphocyte proliferation in nephrotic syndrome.

1981 • 17 citations

Cyclosporine in nephrotic syndrome.

1988 • 15 citations

Serum interleukin-2 levels in a patient with focal segmental glomerulosclerosis

1990 • 14 citations

Soluble IL-2 receptor in patients with primary nephrotic syndrome.

1991 • 6 citations

A HUMAN URINE-DERIVED INTERLEUKIN 1 INHIBITOR

1988 • 5 citations