Absorption of thyrotropin-releasing hormone (TRH) and a TRH prodrug in a human intestinal cell line (Caco-2)

Correlation between oral drug absorption in humans and apparent drug permeability coefficients in human intestinal epithelial (Caco-2) cells

1991 • 1,787 citations

One Hundred and Twenty-Seven Cultured Human Tumor Cell Lines Producing Tumors in Nude Mice23

1977 • 1,556 citations

Epithelial Transport Of Drugs In Cell Culture. I: A Model For Studying The Passive Diffusion Of Drugs Over Intestinal Absorbtive (Caco-2) Cells

1990 • 820 citations

Analysis of Structural Requirements for the Absorption of Drugs and Macromolecules from the Nasal Cavity

1987 • 342 citations

Peptides and the blood-brain barrier: Lipophilicity as a predictor of permeability

1985 • 297 citations

Uptake of the cephalosporin, cephalexin, by a dipeptide transport carrier in the human intestinal cell line, Caco-2

1990 • 224 citations

Prolyl endopeptidase

1983 • 203 citations

Functional epithelial cells in culture

1990 • 202 citations

Absorption of polyethylene glycols 600 through 2000: the molecular weight dependence of gastrointestinal and nasal absorption.

1990 • 168 citations

Prodrugs of peptides. 6. Bioreversible derivatives of thyrotropin-releasing hormone (TRH) with increased lipophilicity and resistance to cleavage by the TRH-specific serum enzyme.

1990 • 78 citations

Thyrotropin-releasing hormone. Biomedical significance.

1989 • 51 citations

Absorption of a vasopressin analogue, 1-deamino-8-d-arginine-vasopressin (dDAVP), in a human intestinal epithelial cell line, CaCO-2

1990 • 48 citations

Biophysical model approaches to mechanistic transepithelial studies of peptides

1990 • 41 citations

TRH: Historical Aspects

1989 • 39 citations

Intestinal absorption mechanisms of thyrotropin-releasing hormone.

1984 • 38 citations

A Comparison of Thyrotropin-Releasing Hormone with Analogs: Influence of Disposition upon Pharmacology

1983 • 31 citations

Prodrugs of peptides. 7. Transdermal delivery of thyrotropin-releasing hormone (TRH) via prodrugs

1990 • 30 citations

Characteristics of tripeptide transport in human jejunal brush-border membrane vesicles

1989 • 28 citations

Kinetics and pattern of degradation of thyrotropin-releasing hormone (TRH) in human plasma.

1990 • 26 citations

Prodrugs of peptides. 8. In vitro study of intestinal metabolism and penetration of thyrotropin-releasing hormone (TRH) and its prodrugs

1990 • 23 citations