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An elevated maternal plasma, but not amniotic fluid, soluble fms-like tyrosine kinase-1 (sFlt-1) at the time of mid-trimester genetic amniocentesis is a risk factor for preeclampsia

Data up to Jan 2025

Published2005
Citations87
References20

Total Citations Per Year

Abstract

References (20)

Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsia

2003 • 3,707 citations

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2000 • 3,189 citations

A Randomized Trial of Bevacizumab, an Anti–Vascular Endothelial Growth Factor Antibody, for Metastatic Renal Cancer

2003 • 2,723 citations

Circulating angiogenic factors and the risk of preeclampsia*

2004 • 2,591 citations

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1999 • 1,855 citations

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1998 • 637 citations

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2002 • 603 citations

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2002 • 588 citations

Elevated Placental Soluble Vascular Endothelial Growth Factor Receptor-1 Inhibits Angiogenesis in Preeclampsia

2004 • 499 citations

First Trimester Placental Growth Factor and Soluble Fms-Like Tyrosine Kinase 1 and Risk for Preeclampsia

2004 • 450 citations

Elevated Serum Soluble Vascular Endothelial Growth Factor Receptor 1 (sVEGFR-1) Levels in Women with Preeclampsia

2003 • 396 citations

Evidence supporting a role for blockade of the vascular endothelial growth factor system in the pathophysiology of preeclampsia

2004 • 362 citations

Plasma soluble vascular endothelial growth factor receptor-1 concentration is elevated prior to the clinical diagnosis of pre-eclampsia

2005 • 337 citations

VEGF165 mediates glomerular endothelial repair

1999 • 294 citations

Expression of vascular endothelial growth factor receptors 1, 2 and 3 in placentas from normal and complicated pregnancies

2001 • 230 citations

Trophoblast Deportation in Human Pregnancy—its Relevance for Pre-eclampsia

1999 • 230 citations

Soluble vascular endothelial growth factor receptor-1 (sFlt-1) is increased throughout gestation in patients who have preeclampsia develop

2004 • 217 citations

Amniotic fluid–soluble vascular endothelial growth factor receptor-1 in preeclampsia

2000 • 133 citations

Amniotic Fluid–Soluble Vascular Endothelial Growth Factor Receptor-1 in Preeclampsia

2000 • 33 citations

Hypertension in pregnancy

1993 • 8 citations

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