A β‐subunit mutation in the acetylcholine receptor channel gate causes severe slow‐channel syndrome

Acetylcholine receptor channel imaged in the open state

1995 • 1,002 citations

Molecular distinction between fetal and adult forms of muscle acetylcholine receptor

1986 • 979 citations

Nicotinic Acetylcholine Receptor an 9 Å Resolution

1993 • 822 citations

Cloning and sequence analysis of calf cDNA and human genomic DNA encoding α-subunit precursor of muscle acetylcholine receptor

1983 • 433 citations

Channel gating governed symmetrically by conserved leucine residues in the M2 domain of nicotinic receptors

1995 • 304 citations

Mutation of the acetylcholine receptor α subunit causes a slow-channel myasthenic syndrome by enhancing agonist binding affinity

1995 • 263 citations

A newly recognized congenital myasthenic syndrome attributed to a prolonged open time of the acetylcholine‐induced ion channel

1982 • 259 citations

Congenital myasthenic syndrome caused by prolonged acetylcholine receptor channel openings due to a mutation in the M2 domain of the epsilon subunit.

1995 • 252 citations

Structure of nicotinic acetylcholine receptors

1993 • 234 citations

HISTOMETRIC ANALYSIS OF THE ULTRASTRUCTURE OF THE NEUROMUSCULAR JUNCTION IN MY ASTHENIA GRAVIS AND IN THE MYASTHENIC SYNDROME*

1971 • 210 citations

A mutated acetylcholine receptor subunit causes neuronal degeneration in C. elegans

1995 • 203 citations

A muscle acetylcholine receptor is expressed in the human cerebellar medulloblastoma cell line TE671

1989 • 186 citations

Maggot's hair and bug's eye: Role of cell interactions and intrinsic factors in cell fate specification

1995 • 180 citations

Isolation of a clone coding for the alpha-subunit of a mouse acetylcholine receptor

1985 • 169 citations

A new stain for quantitative measurement of sprouting at neuromuscular junctions

1978 • 156 citations

Isolation and characterization of a cDNA clone for the complete protein coding region of the delta subunit of the mouse acetylcholine receptor.

1984 • 155 citations

Structure linkage, and sequence of the two genes encoding the delta and gamma subunits of the nicotinic acetylcholine receptor.

1984 • 132 citations

THE SLOW CHANNEL SYNDROME

1987 • 75 citations

Primary structure of the human muscle acetylcholine receptor

1993 • 73 citations

Measurement of junctional acetylcholine receptors in myasthenia gravis: Clinical correlates

1985 • 70 citations

Isolation and characterization of the β and ε subunit genes of mouse muscle acetylcholine receptor

1989 • 69 citations

A leucine‐to‐phenylalanine substitution in the acetylcholine receptor ion channel in a family with the slow‐channel syndrome

1995 • 62 citations

Myasthenic Syndromes Attributed to Mutations Affecting the Epsilon Subunit of the Acetylcholine Receptora

1993 • 42 citations

Anconeus muscle: A human muscle preparation suitable for in‐vitro microelectrode studies

1991 • 39 citations

Neuromuscular plasticity following limb immobilization

1984 • 37 citations

Nucleotide sequence of human muscle acetylcholine receptor β-subunit

1989 • 37 citations

Congenital paucity of secondary synaptic clefts (CPSC) syndrome in 2 adult sibs

1989 • 29 citations

A transgenic mouse model of the slow-channel syndrome

1996 • 28 citations

Nucleotide sequence of the ε-subunit of the mouse muscle nicotinic acetylcholine receptor

1990 • 28 citations

Effects of a monoclonal anti‐acetylcholine receptor antibody on the avian end‐plate.

1989 • 28 citations

The kyoto surprise box

1995 • 11 citations

Five Subunit Genes of the Human Muscle Nicotinic Acetylcholine Receptor Are Mapped to Two Linkage Groups on Chromosomes 2 and 17

1993 • 9 citations