Interleukin-10 and the Monocyte/Macrophage-Induced Inflammatory Response in Septic Shock

APACHE II-A Severity of Disease Classification System

1986 • 12,607 citations

Interleukin 10(IL-10) inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytes.

1991 • 3,812 citations

IL-10 inhibits cytokine production by activated macrophages.

1991 • 2,919 citations

Two types of mouse T helper cell. IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones.

1989 • 2,771 citations

Macrophage deactivation by interleukin 10.

1991 • 1,253 citations

Immune response-associated production of neopterin. Release from macrophages primarily under control of interferon-gamma.

1984 • 1,083 citations

Plasma Cytokine and Endotoxin Levels Correlate with Survival in Patients with the Sepsis Syndrome

1993 • 1,068 citations

Isolation and expression of human cytokine synthesis inhibitory factor cDNA clones: homology to Epstein-Barr virus open reading frame BCRFI.

1991 • 752 citations

Dysregulation of in vitro cytokine production by monocytes during sepsis.

1991 • 747 citations

Biological properties of interleukin 10

1992 • 656 citations

Interleukin 10 (IL-10) inhibits the release of proinflammatory cytokines from human polymorphonuclear leukocytes. Evidence for an autocrine role of tumor necrosis factor and IL-1 beta in mediating the production of IL-8 triggered by lipopolysaccharide.

1993 • 504 citations

Predominant role of tumor necrosis factor-alpha in human monocyte IL-10 synthesis.

1993 • 386 citations

Interleukin-10 production during septicaemia

1994 • 365 citations

How gram-positive organisms cause sepsis

1993 • 42 citations

Improvement of Monocyte Function — A New Therapeutic Approach?

1994 • 41 citations

Enhanced Release of Elastase Is Not Concomitant With Increased Secretion of Granulocyte-Activating Cytokines in Whole Blood From Patients With Sepsis

1994 • 27 citations