Tumor necrosis factor decreases thrombin receptor expression in endothelial cells

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Antibodies, a laboratory manual

1989 • 12,929 citations

Antibodies: A laboratory manual

1989 • 4,532 citations

Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation

1991 • 2,981 citations

Direct expression cloning of vascular cell adhesion molecule 1, a cytokine-induced endothelial protein that binds to lymphocytes

1989 • 1,715 citations

Cytokines and endothelial cell biology

1990 • 1,275 citations

Purification of cachectin, a lipoprotein lipase-suppressing hormone secreted by endotoxin-induced RAW 264.7 cells.

1985 • 833 citations

Two distinct monokines, interleukin 1 and tumor necrosis factor, each independently induce biosynthesis and transient expression of the same antigen on the surface of cultured human vascular endothelial cells.

1986 • 748 citations

Prolonged activation of jun and collagenase genes by tumour necrosis factor-α

1989 • 726 citations

Electrical method for detection of endothelial cell shape change in real time: assessment of endothelial barrier function.

1992 • 424 citations

Tumor necrosis factor receptor-mediated signaling pathways.

1994 • 389 citations

Mechanism of action of human activated protein C, a thrombin-dependent anticoagulant enzyme

1982 • 385 citations

Thrombin stimulates the adherence of neutrophils to human endothelial cells in vitro.

1985 • 380 citations

Tumor necrosis factor leads to the internalization and degradation of thrombomodulin from the surface of bovine aortic endothelial cells in culture

1989 • 337 citations

Changes in Liver-Specific Compared to Common Gene Transcription During Primary Culture of Mouse Hepatocytes

1983 • 316 citations

Mechanism of action of human activated protein C, a thrombin-dependent anticoagulant enzyme

1982 • 308 citations

Thrombin‐induced increase in albumin permeability across the endothelium

1986 • 307 citations

Thrombin-induced expression of endothelial P-selectin and intercellular adhesion molecule-1: a mechanism for stabilizing neutrophil adhesion.

1992 • 296 citations

Correlation between thrombin-induced prostacyclin production and inositol trisphosphate and cytosolic free calcium levels in cultured human endothelial cells.

1987 • 281 citations

The molecular action of tumor necrosis factor-alpha

1991 • 279 citations

Thrombin is an important mediator of platelet aggregation in stenosed canine coronary arteries with endothelial injury.

1989 • 241 citations

Regulation of Thrombin Generation and Functions

1988 • 212 citations

Changes in liver-specific compared to common gene transcription during primary culture of mouse hepatocytes.

1983 • 206 citations

Structure and function of the human platelet thrombin receptor. Studies using monoclonal antibodies directed against a defined domain within the receptor N terminus.

1992 • 190 citations

Thrombin-induced gap formation in confluent endothelial cell monolayers in vitro

1983 • 164 citations

Tumor necrosis factor and interleukin-1 cause a rapid and transient stimulation of c-fos and c-myc mRNA levels in human fibroblasts.

1987 • 150 citations

Homologous desensitization of HEL cell thrombin receptors. Distinguishable roles for proteolysis and phosphorylation.

1992 • 107 citations

Tumor necrosis factor-alpha-mediated decrease in glutathione increases the sensitivity of pulmonary vascular endothelial cells to H2O2.

1992 • 107 citations

Tumor necrosis factor-alpha down-regulates human elastin gene expression. Evidence for the role of AP-1 in the suppression of promoter activity.

1992 • 106 citations

Alpha 6.beta 1 integrin (laminin receptor) is down-regulated by tumor necrosis factor alpha and interleukin-1 beta in human endothelial cells.

1992 • 95 citations

Sex, maps, and imprinting

1991 • 78 citations

Calcium dependence of the thrombin-induced increase in endothelial albumin permeability

1989 • 72 citations

Expression of c-jun protooncogene in human myelomonocytic cells

1989 • 54 citations

Alpha-thrombin-induced pulmonary vasoconstriction

1987 • 47 citations

Propagation of electromagnetic waves of crossroads with a reflector inside a tunnel

1989 • 36 citations

Thrombin-induced shape changes of cultured endothelial cells: Metabolic and functional observations

1983 • 34 citations