Molecular genetic and biochemical evidence for the involvement of the heptapeptide cleavage sequence in determining the reaction profile at two tobacco etch virus cleavage sites in cell-free assays

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Efficientin vitrosynthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter

1984 • 6,459 citations

The rapid generation of oligonucleotide-directed mutations at high frequency using phosphorothioate-modified DNA

1985 • 849 citations

VIRAL PROTEINASES

1988 • 448 citations

Protein 3CD is the major poliovirus proteinase responsible for cleavage of the p1 capsid precursor

1988 • 324 citations

A second proteinase encoded by a plant potyvirus genome.

1989 • 289 citations

Expression and Function of Potyviral Gene Products

1988 • 288 citations

The nucleotide sequence of the coding region of tobacco etch virus genomic RNA: Evidence for the synthesis of a single polyprotein

1986 • 278 citations

The use of phosphorothioate-modified DNA in restriction enzyme reactions to prepare nicked DNA

1985 • 247 citations

A viral cleavage site cassette: identification of amino acid sequences required for tobacco etch virus polyprotein processing.

1988 • 233 citations

Small Nuclear Inclusion Protein Encoded by a Plant Potyvirus Genome Is a Protease

1987 • 211 citations

Molecular genetic analysis of a plant virus polyprotein cleavage site: A model

1989 • 198 citations

Biochemical and mutational analysis of a plant virus polyprotein cleavage site.

1988 • 197 citations

Poliovirus Protein 3CD Is the Active Protease for Processing of the Precursor Protein P1 in vitro

1988 • 181 citations

Proteases involved in the processing of viral polyproteins

1988 • 127 citations

Translation of potyvirus RNA in a rabbit reticulocyte lysate: Identification of nuclear inclusion proteins as products of tobacco etch virus RNA translation and cylindrical inclusion protein as a product of the potyvirus genome

1980 • 111 citations

Proteolytic Processing in the Replication of Polio and Related Viruses

1986 • 99 citations

Processing of the tobacco etch virus 49K protease requires autoproteolysis

1987 • 93 citations

Mutational analysis of tobacco etch virus polyprotein processing: cis and trans proteolytic activities of polyproteins containing the 49-kilodalton proteinase

1988 • 92 citations

Structural domains of the poliovirus polyprotein are major determinants for proteolytic cleavage at Gln-Gly pairs.

1988 • 90 citations

In vitro analysis of tobacco vein mottling virus Nla cistron: Evidence for a virus-encoded protease

1988 • 86 citations

A detailed kinetic analysis of the in Vitro synthesis and processing of encephalomyocarditis virus products

1986 • 84 citations

Proteolytic cleavage of encephalomyocarditis virus capsid region substrates by precursors to the 3C enzyme

1989 • 72 citations

Processing determinants required for in vitro cleavage of the poliovirus P1 precursor to capsid proteins

1987 • 68 citations

Picornaviral processing: Some new ideas

1987 • 49 citations

Site-specific mutations at a picornavirus VP3/VP1 cleavage site disrupt in vitro processing and assembly of capsid precursors

1987 • 42 citations

Analysis of viral RNA isolated from tobacco leaf tissue infected with tobacco etch virus

1983 • 31 citations

A poliovirus mutant defective for self-cleavage at the COOH-terminus of the 3C protease exhibits secondary processing defects

1988 • 27 citations

Vectors for cell-free expression and mutagenesis of protein-coding sequences

1987 • 12 citations