Pharmacokinetics of recombinant human insulin‐like growth factor I given subcutaneously to healthy volunteers and to patients with growth hormone receptor deficiency

Binding proteins for the insulin-like growth factors: Structure, regulation and function

1989 • 565 citations

Short-Term Metabolic Effects of Recombinant Human Insulin-like Growth Factor I in Healthy Adults

1987 • 554 citations

Insulin-like growth factors I and II in healthy man.

1989 • 513 citations

Effects of recombinant insulin-like growth factor I on insulin secretion and renal function in normal human subjects.

1989 • 320 citations

Ontogenesis of somatomedin and insulin receptors in the human fetus.

1983 • 197 citations

PHARM—An interactive graphic program for individual and population pharmacokinetic parameter estimation

1984 • 136 citations

Hormonal and metabolic effects and pharmacokinetics of recombinant insulin-like growth factor-I in growth hormone receptor deficiency/Laron syndrome.

1993 • 126 citations

Recombinant human insulin-like growth factor: testing the somatomedin hypothesis in hypophysectomized rats

1987 • 115 citations

Effects of recombinant human insulin-like growth factor-I (rhIGF-I) on total and free IGF-I concentrations, IGF-binding proteins, and glycemic response in humans.

1992 • 85 citations

Insulin-like growth factor I stimulates growth in normal growing rats

1986 • 79 citations

Hormonal and metabolic effects and pharmacokinetics of recombinant insulin-like growth factor-I in growth hormone receptor deficiency/Laron syndrome

1993 • 50 citations

Treatment with recombinant human insulin-like growth factor I of children with growth hormone receptor deficiency (Laron syndrome). Kabi Pharmacia Study Group on Insulin-like Growth Factor I Treatment in Growth Hormone Insensitivity Syndromes.

1992 • 45 citations

Insulin-like growth factors and their binding proteins in patients with growth hormone receptor deficiency: suggestions for new diagnostic criteria. The Kabi Pharmacia Study Group on Insulin-like Growth Factor I Treatment in Growth Hormone Insensitivity Syndromes.

1992 • 33 citations

Growth hormone insensitivity syndromes: a preliminary report on changes in insulin-like growth factors and their binding proteins during treatment with recombinant insulin-like growth factor I

1993 • 30 citations

Effects of recombinant human insulin-like growth factor-I (rhIGF-I) on total and free IGF-I concentrations, IGF-binding proteins, and glycemic response in humans

1992 • 30 citations

Pharmacokinetic Profile of Recombinant Human Insulin‐Like Growth Factor I Given Subcutaneously in Normal Subjects

1991 • 29 citations

Growth promotion with recombinant insulin‐like growth factor I in Laron syndrome

1993 • 2 citations