Effects of Obesity and Stable Weight Reduction on UCP2 and UCP3 Gene Expression in Humans

Changes in Energy Expenditure Resulting from Altered Body Weight

1995 • 1,926 citations

Uncoupling protein-2: a novel gene linked to obesity and hyperinsulinemia

1997 • 1,647 citations

Adipogenesis and Obesity: Rounding Out the Big Picture

1996 • 1,268 citations

Reduced Rate of Energy Expenditure as a Risk Factor for Body-Weight Gain

1988 • 1,210 citations

Uncoupling protein‐3: a new member of the mitochondrial carrier family with tissue‐specific expression

1997 • 1,067 citations

Skeletal muscle metabolism is a major determinant of resting energy expenditure.

1990 • 879 citations

Peroxisome proliferator-activated receptor gene expression in human tissues. Effects of obesity, weight loss, and regulation by insulin and glucocorticoids.

1997 • 789 citations

Uncoupling Protein-3 Is a Mediator of Thermogenesis Regulated by Thyroid Hormone, β3-Adrenergic Agonists, and Leptin

1997 • 755 citations

UCP3: An Uncoupling Protein Homologue Expressed Preferentially and Abundantly in Skeletal Muscle and Brown Adipose Tissue

1997 • 728 citations

Regulation of PPAR gamma gene expression by nutrition and obesity in rodents.

1996 • 654 citations

Obesity

1997 • 575 citations

Cloning and Characterization of an Uncoupling Protein Homolog: A Potential Molecular Mediator of Human Thermogenesis

1997 • 488 citations

Energy Expenditure and Intake in Infants Born to Lean and Overweight Mothers

1988 • 390 citations

Increased uncoupling protein-2 and -3 mRNA expression during fasting in obese and lean humans.

1997 • 356 citations

Elevated Free Fatty Acids Induce Uncoupling Protein 3 Expression in Muscle: A Potential Explanation for the Effect of Fasting

1998 • 305 citations

Mitochondrial uncoupling protein from mouse brown fat. Molecular cloning, genetic mapping, and mRNA expression.

1985 • 301 citations

The adipocyte: Storage depot or node on the energy information superhighway?

1995 • 298 citations

Reduced sympathetic nervous activity. A potential mechanism predisposing to body weight gain.

1993 • 296 citations

Uncoupling Protein-3 Expression in Rodent Skeletal Muscle Is Modulated by Food Intake but Not by Changes in Environmental Temperature

1998 • 282 citations

Isolation of the uncoupling protein from brown adipose tissue mitochondria

1980 • 262 citations

Complete cDNA-derived amino acid sequence of rat brown fat uncoupling protein.

1986 • 230 citations

Linkage Between Markers in the Vicinity of the Uncoupling Protein 2 Gene and Resting Metabolic Rate in Humans

1997 • 227 citations

Obesity as an adaptation to a high-fat diet: evidence from a cross-sectional study

1994 • 223 citations

The Human Uncoupling Protein-3 Gene

1997 • 174 citations

Methods for Voluntary Weight Loss and Control

1992 • 167 citations

Epinephrine mediates facultative carbohydrate-induced thermogenesis in human skeletal muscle

1989 • 121 citations

Thermogenic response to epinephrine in the forearm and abdominal subcutaneous adipose tissue

1992 • 105 citations

Role of Brown Adipose Tissue Thermogenesis in Control of Thermoregulatory Feeding in Rats: A New Hypothesis That Links Thermostatic and Glucostatic Hypotheses for Control of Food Intake

1995 • 105 citations

Uncoupling protein-2 gene: reduced mRNA expression in intraperitoneal adipose tissue of obese humans

1998 • 98 citations

Principles of Biostatistics

1994 • 87 citations

Mutational analysis of the coding region of the uncoupling protein 2 gene in obese NIDDM patients: Impact of a common amino acid polymorphism on juvenile and maturity onset forms of obesity and insulin resistance

1997 • 74 citations

The topology of the brown adipose tissue mitochondrial uncoupling protein determined with antibodies against its antigenic sites revealed by a library of fusion proteins.

1993 • 70 citations

Mutation screening of the human UCP 2 gene in normoglycemic and NIDDM morbidly obese patients: lack of association between new UCP 2 polymorphisms and obesity in French Caucasians.

1998 • 65 citations

Elevated free fatty acids induce uncoupling protein 3 expression in muscle: a potential explanation for the effect of fasting

1998 • 64 citations

Organisation of the coding exons and mutational screening of the uncoupling protein 3 gene in subjects with juvenile-onset obesity

1998 • 47 citations

mRNA expression of the long and short forms of uncoupling protein-3 in obese and lean humans

1998 • 31 citations

Structure and organization of the human uncoupling protein 2 gene and identification of a common biallelic variant in Caucasian and African-American subjects.

1998 • 26 citations

Uncoupling Protein 2 Region on Chromosome 11q13 Is not Linked to Markers of Obesity in Familial Type 2 Diabetes

1997 • 24 citations