The E-T (Elephant-Tadpole) paradox necessitates the concept of a unit of b-cell function: The protecton

Somatic generation of antibody diversity

1983 • 3,275 citations

Three-Dimensional Structure of an Antigen-Antibody Complex at 2.8 Å Resolution

1986 • 1,173 citations

An immunoglobulin heavy chain variable region gene is generated from three segments of DNA: VH, D and JH

1980 • 872 citations

The Molecular Genetics of the T-Cell Antigen Receptor and T-Cell Antigen Recognition

1986 • 772 citations

Ordered rearrangement of immunoglobulin heavy chain variable region segments.

1984 • 736 citations

Idiotypic Networks and Other Preconceived Ideas

1984 • 543 citations

The immunoglobulin heavy chain variable region (Igh‐V) locus in the mouse. I. One hundred Igh‐V genes comprise seven families of homologous genes

1984 • 537 citations

Regulation of Genome Rearrangement Events during Lymphocyte Differentiation

1986 • 422 citations

Regulation of the Assembly and Expression of Variable-Region Genes

1986 • 402 citations

Correlations between T-cell specificity and the structure of the antigen receptor

1986 • 375 citations

Aberrant rearrangements contribute significantly to the allelic exclusion of immunoglobulin gene expression

1981 • 319 citations

Introduction of a μ immunoglobulin gene into the mouse germ line: Specific expression in lymphoid cells and synthesis of functional antibody

1984 • 304 citations

Transmission and expression of a specific pair of rearranged immunoglobulin μ and κ genes in a transgenic mouse line

1985 • 244 citations

The Genetics of Antibody Diversity

1982 • 214 citations

Rearrangement of genetic information may produce immunoglobulin diversity

1978 • 209 citations

Allelic exclusion and control of endogenous immunoglobulin gene rearrangement in κ transgenic mice

1984 • 184 citations

Regulated progression of a cultured pre-B-cell line to the B-cell stage

1985 • 174 citations

A transgenic immunoglobulin Mu gene prevents rearrangement of endogenous genes

1985 • 169 citations

The immune system: Genes, receptors, signals

1973 • 169 citations

The Generation of Diversity in Phosphorylcholine-Binding Antibodies

1984 • 153 citations

A speculative view of the multicomponent nature of T cell antigen recognition

1986 • 117 citations

Genetic Control of Antibody Variable Regions

1977 • 112 citations

The Molecules of the Immune System

1985 • 91 citations

Immune protection against foot-and-mouth disease virus studied using virus-neutralizing and non-neutralizing concentrations of monoclonal antibodies.

1986 • 87 citations

Contribution of immunoglobulin heavy-chain variable-region genes to antibody diversity

1980 • 62 citations

Reading of D genes in variable frames as a source of antibody diversity

1985 • 60 citations

The antibody enigma

1984 • 58 citations

The T-cell receptor mediating restrictive recognition of antigen

1983 • 57 citations

Formation and maturation of bone marrow lymphocytes.

1975 • 47 citations

The antibody response during amphibian ontogeny

1976 • 45 citations

FIRST ORDER CONSIDERATIONS IN ANALYZING THE GENERATOR OF DIVERSITY

1974 • 45 citations

Immunoglobulin gene ‘remnant’ DNA - implications for antibody gene recombination

1984 • 44 citations

The T Cell and its Receptor

1986 • 39 citations

Immunoglobulin genes in transgenic mice

1985 • 39 citations

Life span of B lymphocytes: the experimental basis for conflicting results.

1986 • 37 citations

Structural Basis for Antigen-Antibody Recognition

1986 • 27 citations

Diversity in the immune system: “Preconceived ideas” or ideas preconceived?

1985 • 18 citations

Models for the rearrangements of immunoglobulin genes: a computer view

1984 • 18 citations

Immunology: Exclusive immunoglobulin genes

1984 • 14 citations