Biophysics of the structure and function of porins

Ionic channels of excitable membranes

1985 • 7,199 citations

Empirical Predictions of Protein Conformation

1978 • 3,167 citations

Molecular basis of bacterial outer membrane permeability

1985 • 2,171 citations

Filtration, diffusion, and molecular sieving through porous cellulose membranes.

1954 • 1,078 citations

Molecular basis of bacterial outer membrane permeability.

1985 • 904 citations

Ionic channels of excitable membranes

1985 • 795 citations

Molecular architecture and functioning of the outer membrane of Escherichia coli and other gram-negative bacteria

1983 • 782 citations

Characterization of the Major Envelope Protein from Escherichia coli

1974 • 743 citations

Covalent lipoprotein from the outer membrane of escherichia coli

1975 • 568 citations

Reconstitution in planar lipid bilayers of a voltage-dependent anion-selective channel obtained from paramecium mitochondria

1976 • 501 citations

Porin channels in Escherichia coli: studies with liposomes reconstituted from purified proteins

1983 • 439 citations

Porin channels in Escherichia coli: studies with beta-lactams in intact cells

1983 • 370 citations

Models for the structure of outer-membrane proteins of Escherichia coli derived from raman spectroscopy and prediction methods

1986 • 365 citations

Identification of the outer membrane protein of E.coli that produces transmembrane channels in reconstituted vesicle membranes

1976 • 362 citations

Structure and Biosynthesis of the Bacterial Cell Wall

1969 • 353 citations

Cell envelope and shape of Escherichia coli: multiple mutants missing the outer membrane lipoprotein and other major outer membrane proteins

1978 • 329 citations

Influence of osmolarity of the growth medium on the outer membrane protein pattern of Escherichia coli

1977 • 326 citations

Outer membrane of Salmonella. Isolation of protein complex that produces transmembrane channels.

1976 • 304 citations

Outer membrane of gram-negative bacteria. XII. Molecular-sieving function of cell wall

1976 • 304 citations

The structure of porin from Rhodobacter capsulatus at 1.8 Å resolution

1991 • 303 citations

Genetic analysis of the ompB locus in Escherichia coli K-12

1981 • 301 citations

Matrix protein from Escherichia coli outer membranes forms voltage-controlled channels in lipid bilayers.

1978 • 298 citations

Influence of cultural conditions and mutations on the composition of the outer membrane proteins ofEscherichia coli

1976 • 294 citations

A comparative study on the genes for three porins of the Escherichia coli outer membrane. DNA sequence of the osmoregulated ompC gene.

1983 • 287 citations

Ion selectivity of gram-negative bacterial porins

1985 • 287 citations

Three-dimensional crystals of an integral membrane protein: an initial x-ray analysis.

1980 • 268 citations

Structure and Function of Porins from Gram-Negative Bacteria

1988 • 265 citations

Effects of Heating in Dodecyl Sulfate Solution on the Conformation and Electrophoretic Mobility of Isolated Major Outer Membrane Proteins from Escherichia coli K-121

1976 • 264 citations

Specificity of diffusion channels produced by lambda phage receptor protein of Escherichia coli.

1980 • 251 citations

Porin from Bacterial and Mitochondrial Outer Membrane

1985 • 246 citations

Effect on solute size on diffusion rates through the transmembrane pores of the outer membrane of Escherichia coli.

1981 • 230 citations

The Nature of the Negative Resistance in Bimolecular Lipid Membranes Containing Excitability-Inducing Material

1970 • 222 citations

Modified reconstitution method used in patch-clamp studies of Escherichia coli ion channels

1989 • 213 citations

Gene sequence of the λ receptor, an outer membrane protein of E. coli K12

1981 • 211 citations

An artificial anchor domain: hydrophobicity suffices to stop transfer

1985 • 206 citations

Role of porins in outer membrane permeability

1987 • 206 citations

Folding patterns of porin and bacteriorhodopsin.

1985 • 206 citations

Influence of molecular size and osmolarity of sugars and dextrans on the synthesis of outer membrane proteins O-8 and O-9 of Escherichia coli K-12

1979 • 203 citations

Escherichia coli K-12 outer membrane protein (OmpA) as a bacteriophage receptor: analysis of mutant genes expressing altered proteins

1984 • 192 citations

Primary structure of theompFgene that codes for a major outer membrane protein ofEscherichia coliK-12

1982 • 187 citations

Complete nucleotide sequence of phoE, the structural gene for the phosphate limitation inducible outer membrane pore protein of Escherichia coli K12

1983 • 173 citations

Pore formation by LamB of Escherichia coli in lipid bilayer membranes

1986 • 167 citations

Outer membrane protein e of Escherichia coli K-12 is co-regulated with alkaline phosphatase

1980 • 167 citations

X-ray diffraction analysis of matrix porin, an integral membrane protein from Escherichia coli outer membranes

1983 • 166 citations

Porin channel triplets merge into single outlets in Escherichia coli outer membranes

1985 • 163 citations

Porin channels in intact cells of Escherichia coli are not affected by Donnan potentials across the outer membrane.

1988 • 160 citations

Secondary structure of a channel-forming protein: porin from E. coli outer membranes.

1985 • 160 citations

Primary structure of major outer membrane protein II (ompA protein) of Escherichia coli K-12.

1980 • 156 citations

Matrix protein in planar membranes: clusters of channels in a native environment and their functional reassembly.

1981 • 154 citations

Nucleotide sequence of the gene ompA coding the outer membrane protein II^*of Escherichia coli K-12

1980 • 151 citations

Ultrastructure of a periodic protein layer in the outer membrane of Escherichia coli.

1977 • 148 citations

Two-dimensional crystal packing of matrix porin

1983 • 145 citations

Outer-Membrane Permeability of Bacteria

1986 • 134 citations

Bacterial outer membranes as model systems

1987 • 131 citations

AN INTRODUCTION TO MOLECULAR ARCHITECTURE AND PERMEABILITY OF ION CHANNELS

1987 • 124 citations

Periplasmic accumulation of truncated forms of outer-membrane PhoE protein of Escherichia coli K-12

1986 • 121 citations

Purification and properties of Pseudomonas aeruginosa porin.

1983 • 121 citations

A barrier model for current flow in lipid bilayer membranes

1973 • 120 citations

Mutations that alter the pore function of the ompF porin of Escherichia coli K12

1988 • 119 citations

Expression of outer membrane protein e of escherichia coli K12 by phosphate limitation

1980 • 118 citations

Pore-forming activity of the Tsx protein from the outer membrane of Escherichia coli. Demonstration of a nucleoside-specific binding site.

1988 • 117 citations

Genetic locus (ompB) affecting a major outer-membrane protein in Escherichia coli K-12

1977 • 116 citations

A patch‐clamp study of ion channels of inner and outer membranes and of contact zones of E. coli, fused into giant liposomes

1989 • 111 citations

Lambda Receptor in the Outer Membrane of Escherichia coli as a Binding Protein for Maltodextrins and Starch Polysaccharides

1980 • 111 citations

Properties of the major outer membrane protein from Neisseria gonorrhoeae incorporated into model lipid membranes.

1983 • 110 citations

[9] Proteins forming large channels from bacterial and mitochondrial outer membranes: Porins and phage lambda receptor protein

1983 • 110 citations

Molecular design of PhoE porin and its functional consequences

1989 • 108 citations

Immunopharmacology and the regulation of leukocyte function

1983 • 105 citations

Densely packed β-structure at the protein-lipid interface of porin is revealed by high-resolution cryo-electron microscopy

1989 • 98 citations

One Single Lysine Residue Is Responsible for the Special Interaction between Polyphosphate and the Outer Membrane Porin PhoE of Escherichia coli

1989 • 97 citations

Genetic identification of the pore domain of the OmpC porin of Escherichia coli K-12

1988 • 94 citations

The orientation of beta-sheets in porin. A polarized Fourier transform infrared spectroscopic investigation

1988 • 90 citations

Gene envY of Escherichia coli K-12 affects thermoregulation of major porin expression

1984 • 87 citations

Bacterial outer membranes as model systems

1988 • 86 citations

The selectivity filter of voltage-dependent channels formed by phosphoporin (PhoE protein) from E. coli.

1986 • 82 citations

Biogenesis and Membrane Topology of Outer Membrane Proteins in Escherichia Coli

1988 • 81 citations

Regulation of the pho regulon of Escherichia coli K-12

1982 • 81 citations

Two bacteriophages which utilize a new Escherichia coli major outer membrane protein as part of their receptor.

1978 • 77 citations

PhoE protein pore of the outer membrane of Escherichia coli K12 is a particularly efficient channel for organic and inorganic phosphate

1982 • 76 citations

Topology of outer membrane pore protein PhoE of Escherichia coli. Identification of cell surface-exposed amino acids with the aid of monoclonal antibodies.

1986 • 75 citations

The voltage‐dependent activity of Escherichia coli porins in different planar bilayer reconstitutions

1989 • 74 citations

Structure of the lc and nmpC outer membrane porin protein genes of lambdoid bacteriophage.

1986 • 73 citations

Cloning and Molecular Characterization of the ompA Gene from Salmonella typhimurium

1983 • 65 citations

Targeting of porin to the outer membrane of Escherichia coli. Rate of trimer assembly and identification of a dimer intermediate.

1988 • 64 citations

Bacteriophage lambda receptor site on the Escherichia coli K-12 LamB protein

1987 • 63 citations

Proton Motive Force Involved in Protein Transport Across the Outer Membrane of Aeromonas salmonicida

1989 • 62 citations

Localization of functional domains in E. coli K-12 outer membrane porins.

1985 • 61 citations

Voltage gating of conductance in lipid bilayers induced by porin from outer membrane of Neisseria gonorrhoeae.

1988 • 59 citations

A comparative study on the phoE genes of three enterobacterial species

1987 • 57 citations

Amino acid sequence homology among the major outer membrane proteins of Escherichia coli.

1984 • 56 citations

Channel-closing activity of porins from Escherichia coli in bilayer lipid membranes

1986 • 56 citations

Interaction between Major Outer Membrane Protein (O‐8) and Lipopolysaccharide in Escherichia coli K12

1980 • 55 citations

Primary structure of major outer-membrane protein I (ompF protein, porin) of Escherichia coli B/r

1982 • 54 citations

Defective growth functions in mutants of Escherichia coli K12 lacking a major outer membrane protein

1977 • 53 citations

Three-dimensional electron diffraction of PhoE porin to 2·8resolution

1990 • 51 citations

Amino terminus of outer membrane PhoE protein: localization by use of a bla-phoE hybrid gene

1984 • 50 citations

Role of the Arg¹⁵⁸ residue of the outer membrane PhoE pore protein of Escherichia coli K 12 in bacteriophage TC 45 recognition and in channel characteristics

1985 • 50 citations

Existence and purification of porin heterotrimers of Escherichia coli K12 OmpC, OmpF, and PhoE proteins

1989 • 48 citations

Demonstration of a bacteriophage receptor site on the Escherichia coli K12 outer‐membrane protein OmpC by the use of a protease

1985 • 47 citations

Three-dimensional reconstruction of maltoporin from electron microscopy and image processing.

1988 • 44 citations

Structural transitions of porin, a transmembrane protein

1984 • 43 citations

Crystallization and preliminary X‐ray analysis of porin from Rhodobacter capsulatus

1989 • 42 citations

Properties of the porin of Haemophilus influenzae type b in planar lipid bilayer membranes

1986 • 42 citations

Conformational Studies on Murein‐Lipoprotein from the Outer Membrane of Escherichia coli

1976 • 42 citations

The crystallization of outer membrane proteins from Escherichia coli. Studies on lamB and ompA gene products.

1984 • 40 citations

Purification and reconstitution in lipid bilayer membranes of an outer membrane, pore-forming protein of Aeromonas salmonicida

1983 • 36 citations

Three Dimensional Structure of a Membrane Pore

1984 • 35 citations

Outer membrane proteins of Escherichia coli K-12: Isolation of a common receptor protein for bacteriophage T6 and colicin K

1978 • 35 citations

Gene encoding a hybrid OmpF-PhoE pore protein in the outer membrane of Escherichia coli K12

1984 • 35 citations

Permeability properties of chemically modified porin trimers from Escherichia coli B.

1981 • 33 citations

Protein Interactions in the Outer Membrane of Escherichia coli

1979 • 33 citations

Double negative and positive control of tsx expression in Escherichia coli

1988 • 33 citations

Isolation and preliminary characterization of wild-type OmpC porin dimers from Escherichia coli K-12

1989 • 31 citations

Infrared spectra of outer and cytoplasmic membranes of Escherichia coli

1974 • 31 citations

Construction of a series of ompF-ompC chimeric genes by in vivo homologous recombination in Escherichia coli and characterization of the translational products

1985 • 31 citations

Role of lysines in ion selectivity of bacterial outer membrane porins

1986 • 31 citations

Molecular mechanisms involved in the transport of antibiotics into bacteria

1988 • 30 citations

Arrangement of Proteins O-8 and O-9 in Outer Membrane of Escherichia coli K-12. Existence of Homotrimers and Heterotrimers

1979 • 30 citations

PhoE protein pores in the outer membrane of Escherichia coli K-12 not only have a preference for Pi and Pi-containing solutes but are general anion-preferring channels

1984 • 28 citations

High-resolution electron diffraction of reconstituted PhoE porin

1988 • 28 citations

Analysis of structure-function relationships in Escherichia coli K12 outer membrane porins with the aid of ompC-phoE and phoE-ompC hybrid genes

1987 • 27 citations

Effects of linker insertions on the biogenesis and functioning of the Escherichia coli outer membrane pore protein PhoE

1987 • 27 citations

Projected structure of the pore-forming OmpC protein from Escherichia coli outer membrane

1985 • 27 citations

The structure of porin from Rhodobacter capsulatus at 0.6 nm resolution

1989 • 27 citations

Chemical modification of matrix porin from Escherichia coli: probing the pore topology of a transmembrane protein.

1982 • 24 citations

The pho-controlled outer membrane porin PhoE does not contain specific binding sites for phosphate or polyphosphates.

1988 • 23 citations

Chemical modification of the anion selectivity of the PhoE porin from the Escherichia coli outer membrane

1984 • 21 citations

Permeation of -Lactam Antibiotics into Escherichia coli, Pseudomonas aeruginosa, and Other Gram-Negative Bacteria

1988 • 21 citations

Construction of a series of ompC-ompF chimeric genes by in vivo homologous recombination in Escherichia coli and characterization of their translational products

1987 • 19 citations

Accessibility of lysyl residues of Escherichia coli B/r porin (OmpF) to covalent labeling reagents of different sizes. An approach for a three-dimensional structure of a channel-forming protein.

1985 • 15 citations

The nucleotide sequence of theSalmonella typhiompC porin gene

1988 • 14 citations

Pore formation by pho‐controlled outer‐membrane proteins of various Enterobacteriaceae in lipid bilayers

1988 • 11 citations

Topographic labelling of pore-forming proteins from the outer membrane of Escherichia coli

1986 • 7 citations