Porin channels in intact cells of Escherichia coli are not affected by Donnan potentials across the outer membrane.

Experiments in molecular genetics

1972 • 28,260 citations

[2] New M13 vectors for cloning

1983 • 5,402 citations

The effect of sodium ions on the electrical activity of the giant axon of the squid

1949 • 3,479 citations

Molecular basis of bacterial outer membrane permeability

1985 • 2,171 citations

Periplasmic space in Salmonella typhimurium and Escherichia coli.

1977 • 563 citations

The β-lactamases of Gram-negative bacteria and their rôle in resistance to β-lactam antibiotics

1976 • 539 citations

Formation of large, ion-permeable membrane channels by the matrix protein (porin) of Escherichia coli

1978 • 515 citations

Porin channels in Escherichia coli: studies with liposomes reconstituted from purified proteins

1983 • 439 citations

Porin channels in Escherichia coli: studies with beta-lactams in intact cells

1983 • 370 citations

Diffusion of beta-lactam antibiotics through the porin channels of Escherichia coli K-12

1985 • 338 citations

Function of the Outer Membrane of Escherichia coli as a Permeability Barrier to Beta-Lactam Antibiotics

1977 • 321 citations

Outer membrane of Salmonella. Isolation of protein complex that produces transmembrane channels.

1976 • 304 citations

Matrix protein from Escherichia coli outer membranes forms voltage-controlled channels in lipid bilayers.

1978 • 298 citations

Ionic selectivity of pores formed by the matrix protein (porin) of Escherichia coli

1979 • 293 citations

Osmotic regulation and the biosynthesis of membrane-derived oligosaccharides in Escherichia coli.

1982 • 224 citations

Studies on the “Diffusion Effect” upon Ionic Distribution. Some Theoretical Considerations

1935 • 181 citations

Sensitivity of Escherichia coli to various β‐lactams is determined by the interplay of outer membrane permeability and degradation by periplasmic β‐lactamases: a quantitative predictive treatment

1987 • 175 citations

Osmotic Swelling of Phospholipid Vesicles Causes Them to Fuse with a Planar Phospholipid Bilayer Membrane

1982 • 159 citations

Matrix protein in planar membranes: clusters of channels in a native environment and their functional reassembly.

1981 • 154 citations

Molecular Specificities of R Factor-Determined Beta-Lactamases: Correlation with Plasmid Compatibility

1974 • 153 citations

Selection, mapping, and characterization of osmoregulatory mutants of Escherichia coli blocked in the choline-glycine betaine pathway

1986 • 135 citations

Genetics of osmoregulation inEscherichia coli: Uptake and biosynthesis of organic osmolytes

1986 • 132 citations

Lateral Mobility and Surface Density of Lipopolysaccharide in the Outer Membrane of Salmonella typhimurium

1974 • 111 citations

[9] Proteins forming large channels from bacterial and mitochondrial outer membranes: Porins and phage lambda receptor protein

1983 • 110 citations

Interactions of Outer Membrane Proteins O-8 and O-9 with Peptidoglycan Sacculus of Escherichia coli K-121

1976 • 84 citations

Regulation of outer membrane protein synthesis in Escherichia coli K-12: deletion of ompC affects expression of the OmpF protein

1984 • 75 citations

Characterisation of channels induced in planar bilayer membranes by detergent solubilised Escherichia coli porins

1985 • 46 citations

Outer membranes of gram-negative bacteria. XV. Transmembrane diffusion rates in lipoprotein-deficient mutants of Escherichia coli

1977 • 30 citations

[21] Transport through the outer membrane of bacteria

1986 • 16 citations

Effects of magnesium and sodium ions on the outer membrane permeability of cephalosporins in Escherichia coli

1986 • 10 citations

Mutant of Escherichia coli deficient in osmoregulation of periplasmic oligosaccharide synthesis

1985 • 10 citations

Estimation of the permeability parameter (C) for the flux of a charged molecule across the Gram-negative bacterial outer membrane

1985 • 5 citations