The Extracellular Concentration of the Anti-epileptic Drug Valproate in the Rat Brain as Determined with Microdialysis and an Automated HPLC Procedure

In vivo determination of extracellular concentration of amino acids in the rat hippocampus. A method based on brain dialysis and computerized analysis

1986 • 428 citations

Determination of Brain Interstitial Concentrations by Microdialysis

1989 • 410 citations

Mechanism of anticonvulsant action of valproate

1982 • 344 citations

Mass transfer in brain dialysis devices—a new method for the estimation of extracellular amino acids concentration

1985 • 299 citations

Cocaine: An in vivo microdialysis evaluation of its acute action on dopamine transmission in rat striatum

1989 • 218 citations

In Vivo Microdialysis as a Technique to Monitor Drug Transport: Correlation of Extracellular Cocaine Levels and Dopamine Overflow in the Rat Brain

1988 • 141 citations

Sodium Valproate, Serum Level and Clinical Effect in Epilepsy: A Controlled Study

1979 • 133 citations

Amino Acids in Rat Striatal Dialysates: Methodological Aspects and Changes After Electroconvulsive Shock

1985 • 126 citations

Disposition of valproic acid in the rat: dose-dependent metabolism, distribution, enterohepatic recirculation and choleretic effect.

1979 • 125 citations

Valproic acid: brain and plasma levels of the drug and its metabolites, anticonvulsant effects and gamma-aminobutyric acid (GABA) metabolism in the mouse.

1982 • 111 citations

Extracellular cocaine and dopamine concentrations are linearly related in rat striatum

1988 • 106 citations

Handbook of Mathematical Formulas

1974 • 97 citations

Distribution of valproic acid and its metabolites in various brain areas of dogs and rats after acute and prolonged treatment.

1983 • 85 citations

Pharmacokinetic-pharmacodynamic modeling of CNS drug effects: An overview

1988 • 83 citations

Plasma concentrations of sodium valproate: Their clinical value

1983 • 73 citations

Measurement of Neurotransmitter Release in vivo

1985 • 57 citations

Automated analysis procedure for valproic acid in blood, serum and brain dialysate by high-performance liquid chromatography with bromomethylmethoxycoumarin as fluorescent label

1989 • 41 citations

Improved automated precolumn derivatization reaction of fatty acids with bromomethylmethoxycoumarin as label

1990 • 30 citations

Distribution of sodium valproate and gaba metabolism in cns of the rat

1984 • 26 citations

Automated solid-phase catalyzed pre-column derivatization of fatty acids for reversed-phase high-performance liquid chromatographic analysis with fluorescence detection

1988 • 25 citations

Rapid shrinkage of rat striatal extracellular space after local kainate application and ischemia as recorded by impedance

1988 • 19 citations

Disposition and pharmacokinetics of valproic acid in rats.

1986 • 11 citations

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