Calsenilin: A calcium-binding protein that interacts with the presenilins and regulates the levels of a presenilin fragment

TGF-β SIGNAL TRANSDUCTION

1998 • 7,582 citations

Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

1995 • 3,985 citations

Candidate Gene for the Chromosome 1 Familial Alzheimer's Disease Locus

1995 • 2,548 citations

Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene

1995 • 2,028 citations

Amyloid, the presenilins and Alzheimer's disease

1997 • 1,370 citations

Recoverin: a Calcium Sensitive Activator of Retinal Rod Guanylate Cyclase

1991 • 569 citations

Prediction of the Coding Sequences of Unidentified Human Genes. II. The Coding Sequences of 40 New Genes (KIAA0041-KIAA0080) Deduced by Analysis of cDNA Clones from Human Cell Line KG-1

1994 • 500 citations

Interfering with Apoptosis: Ca ²⁺ -Binding Protein ALG-2 and Alzheimer's Disease Gene ALG-3

1996 • 481 citations

The presenilins and Alzheimer's disease

1997 • 364 citations

Alternative Cleavage of Alzheimer-Associated Presenilins During Apoptosis by a Caspase-3 Family Protease

1997 • 353 citations

Evidence That Levels of Presenilins (PS1 and PS2) Are Coordinately Regulated by Competition for Limiting Cellular Factors

1997 • 321 citations

Presenilin 1 interaction in the brain with a novel member of the Armadillo family

1997 • 299 citations

Presenilins, the Endoplasmic Reticulum, and Neuronal Apoptosis in Alzheimer's Disease

1998 • 247 citations

Calcium Ionophore Increases Amyloid .beta. Peptide Production by Cultured Cells

1994 • 237 citations

Increased Sensitivity to Mitochondrial Toxin-Induced Apoptosis in Neural Cells Expressing Mutant Presenilin-1 Is Linked to Perturbed Calcium Homeostasis and Enhanced Oxyradical Production

1998 • 222 citations

Calbindin D28k blocks the proapoptotic actions of mutant presenilin 1: Reduced oxidative stress and preserved mitochondrial function

1998 • 216 citations

Endoproteolytic Cleavage and Proteasomal Degradation of Presenilin 2 in Transfected Cells

1997 • 213 citations

Calcium regulates processing of the Alzheimer amyloid protein precursor in a protein kinase C-independent manner.

1994 • 181 citations

Presenilins Are Processed by Caspase-type Proteases

1997 • 155 citations

Requirement of the Familial Alzheimer's Disease Gene PS2 for Apoptosis

1996 • 132 citations

Molecular cloning of hippocalcin, a novel calcium-binding protein of the recoverin family exclusively expressed in hippocampus

1992 • 127 citations

Interaction of Presenilins with the Filamin Family of Actin-Binding Proteins

1998 • 125 citations

Identification of a neuronal calcium sensor (NCS-1) possibly involved in the regulation of receptor phosphorylation

1995 • 100 citations

The presenilin 2 loop domain interacts with the mu-calpain C-terminal region.

1998 • 38 citations