In Silico Simulation of Inhibitor Drug Effects on Nuclear Factor-κB Pathway Dynamics

Missing Pieces in the NF-κB Puzzle

2002 • 3,560 citations

Activators and Target Genes of Rel/NF-кB Transcription Factors

2003 • 3,164 citations

The IκB-NF-κB Signaling Module: Temporal Control and Selective Gene Activation

2002 • 1,805 citations

Proteasome inhibitors: a novel class of potent and effective antitumor agents.

1999 • 1,447 citations

Transcription factors as targets for cancer therapy

2002 • 1,147 citations

NF-κB as a Therapeutic Target in Multiple Myeloma

2002 • 906 citations

Phase I Trial of the Proteasome Inhibitor PS-341 in Patients With Refractory Hematologic Malignancies

2002 • 771 citations

NF-κB as a therapeutic target in cancer

2002 • 550 citations

Nuclear transcription factor-κB as a target for cancer drug development

2002 • 437 citations

Analysis of expression of nuclear factor κB (NF‐κB) in multiple myeloma: downregulation of NF‐κB induces apoptosis

2001 • 162 citations

Cell-Level Pharmacokinetic Model of Granulocyte Colony-Stimulating Factor: Implications for Ligand Lifetime and Potency in Vivo

2003 • 40 citations