Specific Modification of Mitochondrial Protein Thiols in Response to Oxidative Stress

Measurement of protein using bicinchoninic acid

1985 • 17,516 citations

DETERMINATION OF SERUM PROTEINS BY MEANS OF THE BIURET REACTION

1949 • 16,078 citations

Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide.

1990 • 7,068 citations

[70] Determination of glutathione and glutathione disulfide in biological samples

1985 • 2,678 citations

Peroxynitrite oxidation of sulfhydryls.

1991 • 2,479 citations

Redox signaling: Nitrosylation and related target interactions of nitric oxide

1994 • 1,732 citations

[48] Assay of glutathione, glutathione disulfide, and glutathione mixed disulfides in biological samples

1981 • 1,564 citations

Selective Targeting of a Redox-active Ubiquinone to Mitochondria within Cells

2001 • 1,025 citations

Persistent inhibition of cell respiration by nitric oxide: Crucial role ofS-nitrosylation of mitochondrial complex I and protective action of glutathione

1998 • 825 citations

Nitric oxide synthase activity in mitochondria

1997 • 576 citations

The voltage sensor of the mitochondrial permeability transition pore is tuned by the oxidation-reduction state of vicinal thiols. Increase of the gating potential by oxidants and its reversal by reducing agents

1994 • 527 citations

Mechanism of Coupling of Oxidative Phosphorylation and the Membrane Potential of Mitochondria

1969 • 458 citations

Subcellular components: preparation and fractionation;

1972 • 421 citations

Alterations in intracellular thiol homeostasis during the metabolism of menadione by isolated rat hepatocytes

1984 • 411 citations

Protein Sulfhydryls and Their Role in the Antioxidant Function of Protein S-Thiolation

1995 • 409 citations

The effect of nitric oxide on cell respiration: A key to understanding its role in cell survival or death

2000 • 391 citations

Nitric oxide-induced S-nitrosylation of glyceraldehyde-3-phosphate dehydrogenase inhibits enzymatic activity and increases endogenous ADP-ribosylation.

1992 • 390 citations

Superoxide as an intracellular radical sink

1993 • 356 citations

Selective targeting of bioactive compounds to mitochondria

1997 • 344 citations

Mitochondrial Nitric-oxide Synthase Stimulation Causes Cytochrome c Release from Isolated Mitochondria

1999 • 333 citations

Purification and Characterization of a Nitric-oxide Synthase from Rat Liver Mitochondria

1998 • 329 citations

The role of glutathione in the regulation of apoptosis

1999 • 325 citations

A precise method for the determination of whole blood and plasma sulfhydryl groups

1979 • 261 citations

Glutathione Depletion in PC12 Results in Selective Inhibition of Mitochondrial Complex I Activity

2000 • 253 citations

Redox regulation of apoptosis: Impact of thiol oxidation status on mitochondrial function

1997 • 214 citations

Nitric oxide partitioning into mitochondrial membranes and the control of respiration at cytochrome c oxidase

2001 • 211 citations

Oxidative stress and S‐nitrosylation of proteins in cells

2000 • 196 citations

Targeting peptide nucleic acid (PNA) oligomers to mitochondria within cells by conjugation to lipophilic cations: implications for mitochondrial DNA replication, expression and disease

2001 • 167 citations

Quantitation and origin of the mitochondrial membrane potential in human cells lacking mitochondrial DNA

1999 • 158 citations

[12] Native electrophoresis for isolation of mitochondrial oxidative phosphorylation protein complexes

1995 • 151 citations

Peroxynitrite causes calcium efflux from mitochondria which is prevented by Cyclosporin A

1994 • 143 citations

Thermodynamic control of electron flux through mitochondrial cytochrome bc1 complex

1985 • 109 citations

Modulation of AP‐1 activity by nitric oxide (NO) in vitro: NO‐mediated modulation of AP‐1

1994 • 109 citations

Synthesis and Characterization of Thiobutyltriphenylphosphonium Bromide, a Novel Thiol Reagent Targeted to the Mitochondrial Matrix

1995 • 106 citations

Mitochondria. A practical approach

1988 • 96 citations

Alterations to glutathione and nicotinamide nucleotides during the mitochondrial permeability transition induced by peroxynitrite

1996 • 82 citations

General Method to Identify and Enrich Vicinal Thiol Proteins Present in Intact Cells in the Oxidized, Disulfide State

1997 • 81 citations

Protein thiol modification and apoptotic cell death as cGMP-independent nitric oxide (NO) signaling pathways

1995 • 76 citations

Active/de‐active state transition of the mitochondrial complex I as revealed by specific sulfhydryl group labeling

1999 • 72 citations

Relationships between the NAD(P) redox state, fatty acid oxidation, and inner membrane permeability in rat liver mitochondria

1989 • 65 citations

Evidence for the existence of two classes of sulfhydryl groups essential for membrane-bound succinate dehydrogenase activity

1981 • 42 citations

Inhibition of Rat Liver Mitochondrial Permeability Transition by Respiratory Substrates

1995 • 40 citations

Analyses of Muscle Proteins in a Patient with a Mitochondrial Myopathy1

1985 • 6 citations