The metabolic anatomy of Parkinson's disease: Complementary [18F]fluorodeoxyglucose and [18F]fluorodopa positron emission tomographic studies

THE [¹⁴C]DEOXYGLUCOSE METHOD FOR THE MEASUREMENT OF LOCAL CEREBRAL GLUCOSE UTILIZATION: THEORY, PROCEDURE, AND NORMAL VALUES IN THE CONSCIOUS AND ANESTHETIZED ALBINO RAT¹

1977 • 5,986 citations

Graphical Evaluation of Blood-to-Brain Transfer Constants from Multiple-Time Uptake Data

1983 • 3,439 citations

Brain dopamine and the syndromes of Parkinson and Huntington Clinical, morphological and neurochemical correlations

1973 • 2,615 citations

Tomographic measurement of local cerebral glucose metabolic rate in humans with (F‐18)2‐fluoro‐2‐deoxy‐D‐glucose: Validation of method

1979 • 2,396 citations

A PHYSIOLOGICAL MECHANISM OF BRADYKINESIA

1980 • 648 citations

Recent Developments in Parkinson's Disease

1987 • 552 citations

Speculations on the Functional Anatomy of Basal Ganglia Disorders

1983 • 411 citations

Brain dopamine metabolism in patients with Parkinson's disease measured with positron emission tomography.

1986 • 345 citations

Striatal inhomogeneities and basal ganglia function

1986 • 323 citations

The aging human brain

1985 • 248 citations

The metabolic pathology of the AIDS dementia complex

1987 • 234 citations

Scaled Subprofile Model: A Statistical Approach to the Analysis of Functional Patterns in Positron Emission Tomographic Data

1987 • 208 citations

Striatal dopamine distribution in Parkinsonian patients during life

1985 • 198 citations

Metabolic effects of unilateral lesion of the substantia nigra

1981 • 195 citations

Patterns of local cerebral glucose utilization determined in Parkinson's disease by the [¹⁸F]fluorodeoxyglucose method

1984 • 178 citations

Cerebral Metabolism of 6–[¹⁸F]Fluoro‐l‐3,4‐Dihydroxyphenylalanine in the Primate

1987 • 164 citations

Inhibition of <scp>L</scp>‐{¹⁸F}fluorodopa uptake into human brain by amino acids demonstrated by positron emission tomography

1986 • 163 citations

The effect of carbidopa on the pharmacokinetics of intravenously administered levodopa: The mechanism of action in the treatment of parkinsonism

1985 • 157 citations

Amino Acid Transport

1972 • 157 citations

Alterations of regional cerebral blood flow and oxygen metabolism in Parkinson's disease

1985 • 155 citations

Central Dopaminergic Pathways in Hemiparkinsonism Examined by Positron Emission Tomography

1984 • 148 citations

STEELE-RICHARDSON-OLSZEWSKI SYNDROME

1988 • 139 citations

Striatal dopamine metabolism in living monkeys examined by positron emission tomography

1983 • 114 citations

Regional blood flow in herniparkinsonism

1985 • 112 citations

Does levodopa aggravate Parkinson's disease?

1988 • 104 citations

Determination of plasma [18F]-6-fluorodopa during positron emission tomography: Elimination and metabolism in carbidopa treated subjects

1986 • 98 citations

Synthesis of no-carrier-added fluorine- 18 2-fluoro-2-deoxy-D-glucose.

1983 • 98 citations

Local cerebral glucose utilisation in treated and untreated patients with Parkinson's disease.

1984 • 94 citations

Cervical root stimulation in the diagnosis of radiculopathy

1987 • 87 citations

Positron emission tomography in Parkinson's disease: glucose and DOPA metabolism.

1987 • 86 citations

3‐O‐ methyldopa blocks dopa metabolism in rat corpus striatum

1982 • 81 citations

Cerebral Glucose Metabolism as a Function of Age in Man: Influence of the Rate Constants in the Fluorodeoxyglucose Method

1983 • 78 citations

Cerebral Glucose Metabolism in Parkinson’s Disease

1984 • 68 citations

Effect of Vascular Activity in the Determination of Rate Constants for the Uptake of ¹⁸F-Labeled 2-Fluoro-2-Deoxy-D-Glucose: Error Analysis and Normal Values in Older Subjects

1986 • 60 citations

Metabolites of 6-[18F]fluoro-L-dopa in human blood.

1988 • 55 citations

Changes in local cerebral glucose utilization associated with Parkinson's syndrome induced by 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine (MPTP) in the primate

1987 • 55 citations

Evaluation of the Performance Characteristics of the PC 4600 Positron Emission Tomograph

1984 • 49 citations

Local cerebral metabolic effects of L-dopa therapy in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced parkinsonism in monkeys.

1987 • 46 citations

The metabolic anatomy of paraneoplastic cerebellar degeneration

1988 • 37 citations

A double-blind crossover comparison of Sinemet CR4 and standard Sinemet 25/100 in patients with Parkinson's disease and fluctuating motor performance.

1989 • 36 citations

Brain nervous mechanisms involved in the so-called extra pyramidal motor and psychomotor disturbances

1975 • 32 citations

Clinical significance of the relationship between O‐methyldopa levels and levodopa intake

1988 • 29 citations

Cerebral Glucose and Dopa Metabolism in Movement Disorders

1987 • 15 citations

In vivo Studies on Intracellular pH, Focal Flow, and Vessel Diameter in the Cat Cerebral Cortex: Effects of Altered CO₂ and Electrical Stimulation

1987 • 15 citations

Four DNA Polymorphisms on the Short Arm of the X Chromosome: Allele Frequencies in a German and in a Turkish Population

1987 • 13 citations

The synthesis of high radiochemical purity of 2‐[¹⁸F]‐fluoro‐2‐deoxy‐D‐glucose without the use of preparative hplc

1987 • 9 citations

Migraine made severe by some other disease

1962 • 7 citations

CROSS-SECTIONAL ANATOMY

1992 • 4 citations

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