Telomeres, telomerase, and aging: Origin of the theory

The serial cultivation of human diploid cell strains

1961 • 7,886 citations

The limited in vitro lifetime of human diploid cell strains

1965 • 5,595 citations

Telomeres shorten during ageing of human fibroblasts

1990 • 5,530 citations

Identification of a specific telomere terminal transferase activity in tetrahymena extracts

1985 • 3,331 citations

A theory of marginotomy

1973 • 1,770 citations

A telomeric sequence in the RNA of Tetrahymena telomerase required for telomere repeat synthesis

1989 • 1,607 citations

Origin of Concatemeric T7DNA

1972 • 1,591 citations

THE STABILITY OF BROKEN ENDS OF CHROMOSOMES IN ZEA MAYS

1941 • 1,586 citations

The human telomere terminal transferase enzyme is a ribonucleoprotein that synthesizes TTAGGG repeats

1989 • 1,509 citations

Telomere loss: mitotic clock or genetic time bomb?

1991 • 1,144 citations

Telomere end-replication problem and cell aging

1992 • 1,044 citations

[Principle of marginotomy in template synthesis of polynucleotides].

1971 • 566 citations

The remaking of chromosomes

1938 • 416 citations

Telomeres, Telomerase, and Immortality

1995 • 393 citations

Telomeres: No end in sight

1994 • 322 citations

Mammalian telomere dynamics: healing, fragmentation shortening and stabilization

1994 • 161 citations

Chromosome ends in Drosophila without telomeric DNA sequences.

1990 • 139 citations

Growth and death of diploid and transformed human fibroblasts

1975 • 39 citations

Telomerase and Telomere-length Regulation: Lessons from Small Eukaryotes to Mammals

1993 • 26 citations

Telomeres — what's new at the end?

1991 • 18 citations

[The immune response and the process of marginotomy in lymphoid cells].

1972 • 14 citations