Inhibition of T Cell Activation by MHC Blockade

Structure of the human class I histocompatibility antigen, HLA-A2

1987 • 3,453 citations

Binding of immunogenic peptides to Ia histocompatibility molecules

1985 • 1,209 citations

A hypothetical model of the foreign antigen binding site of Class II histocompatibility molecules

1988 • 1,161 citations

A Molecular Basis for MHC Class II—Associated Autoimmunity

1988 • 707 citations

The Relation Between Major Histocompatibility Complex (MHC) Restriction and the Capacity of Ia to Bind Immunogenic Peptides

1987 • 696 citations

Transglutaminase is essential in receptor-mediated endocytosis of α2-macroglobulin and polypeptide hormones

1980 • 535 citations

T-cell antigenic sites tend to be amphipathic structures.

1985 • 527 citations

T-cell epitope of the autoantigen myelin basic protein that induces encephalomyelitis

1986 • 471 citations

Isolation and characterization of antigen-la complexes involved in T cell recognition

1986 • 470 citations

Antigen recognition in autoimmune encephalomyelitis and the potential for peptide-mediated immunotherapy

1989 • 394 citations

Two distinct subpopulations of endosomes involved in membrane recycling and transport to lysosomes

1988 • 377 citations

Structural characteristics of an antigen required for its interaction with Ia and recognition by T cells

1987 • 367 citations

Prediction of major histocompatibility complex binding regions of protein antigens by sequence pattern analysis.

1989 • 310 citations

Mechanisms influencing the immunodominance of T cell determinants.

1988 • 227 citations

Interaction of peptide antigens and class II major histocompatibility complex antigens

1986 • 221 citations

Antigenic competition at the level of peptide-Ia binding.

1986 • 216 citations

In vivo competition between self peptides and foreign antigens in T-cell activation

1988 • 216 citations

Structural model of HLA-DR1 restricted T cell antigen recognition

1988 • 172 citations

Direct binding of influenza peptides to class I HLA molecules

1989 • 149 citations

Prevention of experimental encephalomyelitis with peptides that block interaction of T cells with major histocompatibility complex proteins.

1989 • 135 citations

Chemically related antigens compete for presentation by accessory cells to T cells.

1982 • 121 citations

Peptide competition for antigen presentation

1990 • 101 citations

Synthetic peptides as antigens and competitors in recognition by H-2-restricted cytolytic T cells specific for HLA.

1988 • 97 citations

Immunological activity of covalently linked T-cell epitopes

1990 • 95 citations

Competition for antigen presentation in living cells involves exchange of peptides bound by class II MHC molecules

1989 • 94 citations

Physical association between MHC class I molecules and immunogenic peptides

1989 • 91 citations

Turnover of Ia-peptide complexes is facilitated in viable antigen-presenting cells: biosynthetic turnover of Ia vs. peptide exchange.

1989 • 87 citations

Autoimmune T cells: Immune recognition of normal and variant peptide epitopes and peptide-based therapy

1989 • 81 citations

Interaction of an immunodominant epitope with Ia molecules in T-cell activation.

1988 • 78 citations

Lack of detectable endocytosis of B lymphocyte MHC class II antigens using an antibody-independent technique.

1990 • 66 citations

Structural requirements for the interaction between peptide antigens and I-Ed molecules.

1989 • 65 citations

Selective modification of a private I-A allo-stimulating determinant(s) upon association of antigen with an antigen-presenting cell.

1984 • 45 citations

Processing and Presentation of Antigens

1988 • 33 citations

Immunogenetics of HLA-associated diseases.

1988 • 28 citations

Recycling of Histocompatibility Molecules and Antigen Presentation

1988 • 4 citations