The pharmacological and biochemical activity of 4-amino-4-deoxy-10-methyl-pteroylaspartic acid

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

ENZYMATIC REDUCTION OF FOLIC ACID AND DIHYDROFOLIC ACID TO TETRAHYDROFOLIC ACID

1957 • 416 citations

Specific Binding of 4-Amino Folic Acid Analogues by Folic Acid Reductase

1961 • 389 citations

THE INHIBITION OF ARGINASE BY AMINO ACIDS

1945 • 327 citations

Analogs of Pteroylglutamic Acid. III. 4-Amino Derivatives

1949 • 287 citations

Enzymatic Reduction of Dihydrofolic Acid

1958 • 251 citations

ZONE BEHAVIOR OF ENZYMES

1943 • 235 citations

Studies on the Inhibition of Dihydrofolate Reductase by the Folate Antagonists

1964 • 176 citations

THE BIOCHEMICAL, CELLULAR, AND PHARMACOLOGICAL ACTION AND EFFECTS OF THE FOLIC ACID ANTAGONISTS.

1963 • 156 citations

Further Studies on Dihydrofolic Reductase

1963 • 138 citations

Quantitative problems in biochemistry

1981 • 132 citations

The Role of Dihydrofolic Reductase in the Metabolism of One-Carbon Units^*

1963 • 81 citations

The association of increased dihydrofolate reductase with amethopterin resistance in mouse leukemia.

1962 • 72 citations

The Mechanism of Binding of Folate Analogues by Folate Reductase

1963 • 60 citations

Analogs of Pteroylglutamic Acid. I. N¹⁰-Alkylpteroic Acid and Derivatives

1948 • 53 citations

The relation of folic acid reductase to aminopterin toxicity.

1962 • 36 citations

Studies on the Biological Interrelationships of Folic Acid, Citrovorum Factor, and the Antimetabolite, Aminopterin<xref ref-type="fn" rid="fn1"><sup>2</sup></xref>

1952 • 31 citations

Quantitative Evaluation of Chemotherapeutic Agents Against Advanced Leukemia in Mice

1958 • 30 citations

Further observations of the binding and inhibition of dihydrofolic reductase by folic acid antagonists

1964 • 28 citations

A hypothesis on a possible competitive relation between DNA synthesis and protein synthesis.

1960 • 23 citations

Relationship between Basicity of Certain Folate Analogues and Their Affinities for Folate Reductase

1963 • 22 citations

The inactivation of folic acid antagonists by normal and leukaemic cells

1960 • 17 citations

Comparative effect of amethopterin and its 3',5'-dichloro derivative on purine biosynthesis in leukemic mice.

1960 • 13 citations

The nature of aminopterin inactivated by normal and leukaemic tissues

1960 • 10 citations

Quantitative problems in biochemistry

1957 • 6 citations

Incorporation of formate-C-14 in normal and leukemic mice during extended treatment with amethopterin and 3',5'-dichloramethopterin.

1962 • 3 citations

Effect of orally administered 3', 5'-dichloroamethopterin on formate-C14 incorporation in leukemic mice.

1960 • 3 citations