Phosphorylation of c-Src on Tyrosine 527 by Another Protein Tyrosine Kinase

Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice

1991 • 2,028 citations

Improved retroviral vectors for gene transfer and expression.

1989 • 1,997 citations

Activation and suppression of pp60c-src transforming ability by mutation of its primary sites of tyrosine phosphorylation

1987 • 648 citations

Cloning of a complementary DNA for a protein-tyrosine kinase that specifically phosphorylates a negative regulatory site of p60c-src

1991 • 630 citations

Tyrosine phosphorylation regulates the biochemical and biological properties of pp60c-src

1987 • 567 citations

Tyr ⁵²⁷ Is Phosphorylated in pp60 ^{c- src} : Implications for Regulation

1986 • 567 citations

Isolation of monoclonal antibodies that recognize the transforming proteins of avian sarcoma viruses

1983 • 518 citations

Activation of the pp60c-src kinase by middle T antigen binding or by dephosphorylation.

1985 • 439 citations

Cell transformation by pp60c-src mutated in the carboxy-terminal regulatory domain

1987 • 410 citations

Characterization of sites for tyrosine phosphorylation in the transforming protein of Rous sarcoma virus (pp60v-src) and its normal cellular homologue (pp60c-src).

1981 • 363 citations

Structural analysis of the avian sarcoma virus transforming protein: sites of phosphorylation

1979 • 319 citations

A Protein Tyrosine Kinase Involved in Regulation of pp60c-src function

1989 • 309 citations

Dephosphorylation or antibody binding to the carboxy terminus stimulates pp60c-src.

1986 • 257 citations

Genetics of src: Structure and Functional Organization of a Protein Tyrosine Kinase

1989 • 197 citations

Activation of the oncogenic potential of the avian cellular src protein by specific structural alteration of the carboxy terminus.

1987 • 179 citations

Low Level of Cellular Protein Phosphorylation by Nontransforming Overproduced p60^c-src

1985 • 176 citations

Overexpressed pp60c-src can induce focus formation without complete transformation of NIH 3T3 cells.

1985 • 171 citations

Monoclonal antibodies to Rous sarcoma virus pp60src react with enzymatically active cellular pp60src of avian and mammalian origin

1984 • 163 citations

Neither arginine nor histidine can carry out the function of lysine-295 in the ATP-binding site of p60src.

1986 • 156 citations

Altered sites of tyrosine phosphorylation in pp60c-src associated with polyomavirus middle tumor antigen.

1986 • 147 citations

Cell growth and division. A practical approach.

1990 • 135 citations

Altered tyrosine 527 phosphorylation and mitotic activation of p60c-src

1991 • 122 citations

Enzymatically inactive p60c-src mutant with altered ATP-binding site is fully phosphorylated in its carboxy-terminal regulatory region

1987 • 117 citations

A recombinant murine retrovirus for simian virus 40 large T cDNA transforms mouse fibroblasts to anchorage-independent growth

1986 • 101 citations

Characterization of avian and viral p60src proteins expressed in yeast.

1987 • 84 citations

Association of p60fyn with middle tumor antigen in murine polyomavirus-transformed rat cells

1989 • 72 citations

Deletions within the amino-terminal half of the c-src gene product that alter the functional activity of the protein.

1989 • 62 citations

Investigation of factors that influence phosphorylation of pp60c-src on tyrosine 527.

1988 • 54 citations

Avian pp60c-src is more active when expressed in yeast than in vertebrate fibroblasts.

1987 • 28 citations